Metals and the Integrity of a Biological Coating: The Cuticle of Mussel Byssus
Open accessAbstract
The cuticle of mussel byssal threads is a robust natural coating that combines high extensibility with high stiffness and hardness. In this study, fluorescence microscopy and elemental analysis were exploited to show that the 3,4-dihydroxyphenyl-L-alanine (dopa) residues of mussel foot protein-1 colocalize with Fe and Ca distributions in the cuticle of Mytilus galloprovincialis mussel byssal threads. Chelated removal of Fe and Ca from the cuticle of intact threads resulted in a 50% reduction in cuticle hardness, and thin sections subjected to the same treatment showed a disruption of cuticle integrity. Dopa-metal complexes may provide significant interactions for the integrity of composite cuticles deformed under tension.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
On certain specific inorganic biosubstitute surfaces, such as negatively charged oxidized silicone, electrostatic interaction from protonated amino groups can enhance adhesion of biomolecules to the surface.
“Meanwhile, on certain specific surfaces of inorganic biosubstitutes (e.g., negatively charged oxidized silicone), the electrostatic interaction from protonated amino group can also enhance the adhesion of biomolecules to the surface of biosubstitutes [62, 67].”
From Polydopamine-Assisted Surface Modification for Bone Biosubstitutes (2016) · cites this paper as [67]
The Introduction and Discussion (page numbers unavailable) address metal–dopa interactions and the mechanical integrity of mussel byssal cuticles. Searches for protonated amino groups, electrostatic adhesion, and oxidized silicone found no passage addressing adhesion to the claimed inorganic surface. (LLM, conf=0.74)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Leyland, A., & Matthews, A. (2000) · Wear · doi:10.1016/s0043-1648(00)00488-9 · Cited by 3,102 · see citing works
Single-molecule mechanics of mussel adhesion
Lee, H., Scherer, N. F., & Messersmith, P. B. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605552103 · Cited by 2,112 · see citing works
A reversible wet/dry adhesive inspired by mussels and geckos
Lee, H., Lee, B. P., & Messersmith, P. B. (2007) · Nature · doi:10.1038/nature05968 · Cited by 2,043 · see citing works
Stability constants of metal-ion complexes
Furlani, C. (1965) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)80434-9 · Cited by 1,862 · see citing works
Inorganic Semiconductors for Flexible Electronics
Sun, Y., & Rogers, J. A. (2007) · Advanced Materials · doi:10.1002/adma.200602223 · Cited by 879 · see citing works
Metal‐Mediated Cross‐Linking in the Generation of a Marine‐Mussel Adhesive
Sever, M. J., Weisser, J. T., Monahan, J., Srinivasan, S., & Wilker, J. J. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200352759 · Cited by 486 · see citing works
Mussel Adhesion: Finding the Tricks Worth Mimicking
Waite, J. H., Holten‐Andersen, N., Jewhurst, S. A., & Sun, C. (2005) · The Journal of Adhesion · doi:10.1080/00218460590944602 · Cited by 412 · see citing works
Self-citationAvdeef, A., Sofen, S. R., Bregante, T. L., & Raymond, K. N. (1978) · Journal of the American Chemical Society · doi:10.1021/ja00485a018 · Cited by 313 · see citing works
(2006) · Wiley eBooks · doi:10.1002/3527608478 · Cited by 282 · see citing works
Extensible Collagen in Mussel Byssus: A Natural Block Copolymer
Coyne, K. J., Qin, X., & Waite, J. H. (1997) · Science · doi:10.1126/science.277.5333.1830 · Cited by 264 · see citing works
Self-citationSimplified Polymer Mimics of Cross-Linking Adhesive Proteins
Westwood, G., Horton, T. N., & Wilker, J. J. (2007) · Macromolecules · doi:10.1021/ma0703002 · Cited by 232 · see citing works
Protective coatings on extensible biofibres
Holten‐Andersen, N., Fantner, G. E., Hohlbauch, S. V., Waite, J. H., & Zok, F. W. (2007) · Nature Materials · doi:10.1038/nmat1956 · Cited by 228 · see citing works
Self-citationIndependent Control of Rigidity and Toughness of Polymeric Hydrogels
Kong, H. J., Wong, E., & Mooney, D. J. (2003) · Macromolecules · doi:10.1021/ma034137w · Cited by 224 · see citing works
The coccidian oocyst: a tough nut to crack!
Belli, S. I., Smith, N. C., & Ferguson, D. J. P. (2006) · Trends in Parasitology · doi:10.1016/j.pt.2006.07.004 · Cited by 192 · see citing works
McDowell, L. M., Burzio, L. A., Waite, J. H., & Schaefer, J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.29.20293 · Cited by 181 · see citing works
Self-citationTaylor, S. W., Luther, G. W., & Waite, J. H. (1994) · Inorganic Chemistry · doi:10.1021/ic00103a032 · Cited by 165 · see citing works
Self-citationKushner, A. M., Gabuchian, V., Johnson, E. G., & Guan, Z. (2007) · Journal of the American Chemical Society · doi:10.1021/ja0742176 · Cited by 150 · see citing works
Critical role of zinc in hardening of Nereis jaws
Broomell, C. C., Mattoni, M. A., Zok, F. W., & Waite, J. H. (2006) · Journal of Experimental Biology · doi:10.1242/jeb.02373 · Cited by 139 · see citing works
Self-citationQin, X., Coyne, K. J., & Waite, J. H. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.51.32623 · Cited by 138 · see citing works
Self-citationMapping Chemical Gradients within and along a Fibrous Structural Tissue, Mussel Byssal Threads
Sun, C., & Waite, J. H. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508674200 · Cited by 123 · see citing works
Self-citationBelli, S. I., Wallach, M. G., Luxford, C., Davies, M. J., & Smith, N. C. (2003) · Eukaryotic Cell · doi:10.1128/ec.2.3.456-464.2003 · Cited by 113 · see citing works
Monahan, J., & Wilker, J. J. (2004) · Langmuir · doi:10.1021/la0362728 · Cited by 111 · see citing works
Messori, M., Toselli, M., Pilati, F., Fabbri, E., Fabbri, P., Pasquali, L., & Nannarone, S. (2003) · Polymer · doi:10.1016/j.polymer.2003.12.006 · Cited by 108 · see citing works
Seasonal variation in mussel byssal thread mechanics
Moeser, G. M., & Carrington, E. (2006) · Journal of Experimental Biology · doi:10.1242/jeb.02234 · Cited by 103 · see citing works
Mussel-designed Protective Coatings for Compliant Substrates
Holten‐Andersen, N., & Waite, J. H. (2008) · Journal of Dental Research · doi:10.1177/154405910808700808 · Cited by 94 · see citing works
Self-citationFerguson, D. J. P., Belli, S. I., Smith, N. C., & Wallach, M. G. (2003) · International Journal for Parasitology · doi:10.1016/s0020-7519(03)00185-1 · Cited by 92 · see citing works
Coating Proteins: Structure and Cross-Linking in fp-1 from the Green Shell Mussel Perna canaliculus,
Zhao, H., & Waite, J. H. (2005) · Biochemistry · doi:10.1021/bi051530g · Cited by 73 · see citing works
Self-citationConstraint Effects on Thin Film Channel Cracking Behavior
Tsui, T. Y., McKerrow, A. J., & Vlassak, J. J. (2005) · Journal of materials research/Pratt's guide to venture capital sources · doi:10.1557/jmr.2005.0317 · Cited by 56 · see citing works
Effect of Group II Metal Cations on Catecholate Oxidation
Lebedev, A. V., Ivanova, M. V., Timoshin, A. A., & Ruuge, E. K. (2007) · ChemPhysChem · doi:10.1002/cphc.200700296 · Cited by 47 · see citing works
Yamada, K., Abe, T., & Tanizawa, Y. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.05.069 · Cited by 45 · see citing works
Fabbri, P., Singh, B., Leterrier, Y., Månson, J. ‐. E., Messori, M., & Pilati, F. (2005) · Surface and Coatings Technology · doi:10.1016/j.surfcoat.2005.10.003 · Cited by 32 · see citing works
Coating of jute with natural rubber
Das, D., Datta, M., Chavan, R. B., & Datta, S. K. (2005) · Journal of Applied Polymer Science · doi:10.1002/app.22048 · Cited by 30 · see citing works
The extensible alloscutal cuticle of the tick, Ixodes ricinus
Andersen, S. O., & Roepstorff, P. (2005) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2005.05.009 · Cited by 29 · see citing works
The fluorescent oxidation products of dihydroxyphenylalanine and its esters
Smith, G. J., & Haskell, T. G. (2000) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/s1011-1344(00)00020-8 · Cited by 18 · see citing works
Nano-Mechanical Investigation of the Byssal Cuticle, a Protective Coating of a Bio-Elastomer
Holten‐Andersen, N., Slack, N. L., Zok, F. W., & Waite, J. H. (2004) · MRS Proceedings · doi:10.1557/proc-841-r3.7/y3.7 · Cited by 8 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 20
- [9]Holten-Andersen N Fantner GE Hohlbauch S Waite JH Zok FW Nat. Mater 2007 669 672 17618290
- [10]Moeser GM Carrington E J. Exp. Biol 2006 209 1996 2003 16651564
- [12]Coyne KJ Qin X-X Waite JH Science 1997 277 1830 1832 9295275
- [13]Holten-Andersen N Waite JH J. Dent. Res 2008 87 701 709 18650539 PMC2562761
- [14]Smith GJ Haskell TG J. Photochem. Photobiol. B 2000 55 103 108 10942073
- [15]Andersen SO Roepstorff P Insect Biochem. Mol. Biol 2005 35 1181 1188 16102423
- [16]Belli SI Wallach MG Luxford C Davies MJ Smith NC Eukaryotic Cell 2003 2 456 464 12796290 PMC161462
- [17]Ferguson DJP Belli SI Smith NC Wallach MG Int. J. Parasitol 2003 33 1329 1340 14527516
- [18]Belli SI Smith NC Ferguson DJP Trends Parasitol 2006 22 416 423 16859995
- [19]Sun C Waite JH J. Biol. Chem 2005 280 39332 39336 16166079
- [20]Qin X-X Coyne KJ Waite JH J. Biol. Chem 1997 272 32623 32627 9405478
- [24]Sever MJ Weisser JT Monahan J Srinivasan S Wilker JJ Angew. Chem., Int. Ed 2004 43 448 450 14735531
- [26]Lee H Scherer NF Messersmith PB Proc. Natl. Acad. Sci. U.S.A 2006 103 12999 13003 16920796 PMC1559742
- [28]Kushner AM Gabuchian V Johnson EG Guan Z J. Am. Chem. Soc 2007 129 14110 14111 17973379 PMC3396586
- [29]Zhao H Waite JH Biochemistry 2005 44 15915 15923 16313194 PMC1892533
- [30]Monahan J Wilker JJ Langmuir 2004 20 3724 3729 15875406
- [32]Lee H Lee BP Messersmith PB Nature 2007 448 338 341 17637666
- [33]McDowell LM Burzio LA Waite JH Schaefer J J. Biol. Chem 1999 274 20293 20295 10400649
- [34]Lebedev AV Ivanova MV Timoshin AA Ruuge EK ChemPhysChem 2007 8 1863 1869 17634998
- [37]Broomell CC Mattoni MA Zok FW Waite JH J. Exp. Biol 2006 209 3219 3225 16888069 PMC1865513
Cited by
Sorted by citations
Mussel-Inspired Adhesives and Coatings
Lee, B. P., Messersmith, P. B., Israelachvili, J. N., & Waite, J. H. (2011) · Annual Review of Materials Research · doi:10.1146/annurev-matsci-062910-100429 · Cited by 1,668 · see citing works
Self-citationHolten-Andersen, N., Harrington, M. J., Birkedal, H., Lee, B. P., Messersmith, P. B., Lee, K. Y. C., & Waite, J. H. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015862108 · Cited by 1,597 · see citing works
Self-citationIron-Clad Fibers: A Metal-Based Biological Strategy for Hard Flexible Coatings
Harrington, M. J., Masic, A., Holten-Andersen, N., Waite, J. H., & Fratzl, P. (2010) · Science · doi:10.1126/science.1181044 · Cited by 1,000 · see citing works
Self-citationLiu, Z., Meyers, M. A., Zhang, Z., & Ritchie, R. O. (2017) · Progress in Materials Science · doi:10.1016/j.pmatsci.2017.04.013 · Cited by 889 · see citing works
The chemistry behind catechol-based adhesion
Saiz‐Poseu, J., Mancebo‐Aracil, J., Nador, F., Busqué, F., & Ruiz‐Molina, D. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201801063 · Cited by 850 · see citing works
Mussel‐Inspired Polydopamine Coating as a Universal Route to Hydroxyapatite Crystallization
Ryu, J., Ku, S. H., Lee, H., & Park, C. B. (2010) · Advanced Functional Materials · doi:10.1002/adfm.200902347 · Cited by 778 · see citing works
Jack of all trades: versatile catechol crosslinking mechanisms.
Yang, J., Stuart, M. A. C., & Kamperman, M. (2014) · Chemical Society Reviews · doi:10.1039/c4cs00185k · Cited by 484 · see citing works
Catechols as versatile platforms in polymer chemistry
Faure, E., Falentin-Daudré, C., Jérôme, C., Lyskawa, J., Fournier, D., Woisel, P., & Detrembleur, C. (2013) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.06.004 · Cited by 616 · see citing works
Strong reversible Fe <sup>3+</sup> -mediated bridging between dopa-containing protein films in water
Zeng, H., Hwang, D. S., Israelachvili, J. N., & Waite, J. H. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1007416107 · Cited by 517 · see citing works
Self-citationTransition-metal coordinate bonds for bioinspired macromolecules with tunable mechanical properties
Khare, E., Holten‐Andersen, N., & Buehler, M. J. (2021) · Nature Reviews Materials · doi:10.1038/s41578-020-00270-z · Cited by 361 · see citing works
Self-citationCheng, L., Han, F., Li, D., Li, W., Sun, Q., Zhang, X., & Lu, A. (2012) · Nanoscale · doi:10.1039/c2nr33043a · Cited by 353 · see citing works
Mussel-Inspired Materials: Self-Healing through Coordination Chemistry.
Krogsgaard, M., Nue, V., & Birkedal, H. (2016) · Chemistry · doi:10.1002/chem.201503380 · Cited by 289 · see citing works
The Mechanical Role of Metal Ions in Biogenic Protein‐Based Materials
Degtyar, E., Harrington, M. J., Politi, Y., & Fratzl, P. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201404272 · Cited by 306 · see citing works
A natural biological adhesive from snail mucus for wound repair
Deng, T., Gao, D., Song, X., Zhou, Z., Zhou, L., Tao, M., Jiang, Z., Yang, L., Luo, L., Zhou, A., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-35907-4 · Cited by 289 · see citing works
Synthesis and bio-functionalization of magnetic nanoparticles for medical diagnosis and treatment
Schladt, T. D., Schneider, K., Schild, H., & Tremel, W. (2011) · Dalton Transactions · doi:10.1039/c0dt00689k · Cited by 285 · see citing works
Protein- and Metal-dependent Interactions of a Prominent Protein in Mussel Adhesive Plaques
Hwang, D. S., Zeng, H., Mašić, A., Harrington, M. J., Israelachvili, J. N., & Waite, J. H. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.133157 · Cited by 281 · see citing works
Self-citationPhysical and Chemical Factors Influencing the Printability of Hydrogel-based Extrusion Bioinks
Lee, S. C., Gillispie, G. J., Prim, P. M., & Lee, S. J. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00015 · Cited by 264 · see citing works
Tissue adhesives: From research to clinical translation
Bal-Ozturk, A., Cecen, B., Avci-Adali, M., Topkaya, S. N., Alarcin, E., Yasayan, G., Li, Y.-C. E., Bulkurcuoglu, B., Akpek, A., Avci, H., et al. (2021) · Nano Today · doi:10.1016/j.nantod.2020.101049 · Cited by 246 · see citing works
Mechanics of metal-catecholate complexes: The roles of coordination state and metal types
Xu, Z. (2013) · Scientific Reports · doi:10.1038/srep02914 · Cited by 231 · see citing works
Ryu, S., Lee, Y., Hwang, J., Hong, S., Kim, C.-S., Park, T. G., Lee, H., & Hong, S. H. (2011) · Advanced Materials · doi:10.1002/adma.201004228 · Cited by 212 · see citing works
Liu, H., Xi, P., Xie, G., Shi, Y., Hou, F., Huang, L., Chen, F., Zeng, Z., Shao, C., & Wang, J. (2012) · The Journal of Physical Chemistry C · doi:10.1021/jp2102226 · Cited by 207 · see citing works
Bio-mimetic mechanisms of natural hierarchical materials: A review
Chen, Q., & Pugno, N. M. (2012) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2012.10.012 · Cited by 194 · see citing works
Bae, K. H., Kim, Y. B., Lee, Y., Hwang, J., Park, H., & Park, T. G. (2010) · Bioconjugate Chemistry · doi:10.1021/bc900424u · Cited by 193 · see citing works
Bae, K. H., Lee, K., Kim, C.-S., & Park, T. G. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.09.039 · Cited by 188 · see citing works
Song, P., Xu, Z., Dargusch, M. S., Chen, Z., Wang, H., & Guo, Q. (2017) · Advanced Materials · doi:10.1002/adma.201704661 · Cited by 188 · see citing works
Recent Advances in a Polydopamine-Mediated Antimicrobial Adhesion System
Singh, I., Dhawan, G., Gupta, S., & Kumar, P. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.607099 · Cited by 163 · see citing works
Marine mussel adhesion: biochemistry, mechanisms, and biomimetics
Bandara, N., Zeng, H., & Wu, J. (2012) · Journal of Adhesion Science and Technology · doi:10.1080/01694243.2012.697703 · Cited by 158 · see citing works
Ball, V., Frari, D. D., Michel, M., Buehler, M. J., Toniazzo, V., Singh, M. K., Gracio, J. J. D. A., & Ruch, D. (2011) · BioNanoScience · doi:10.1007/s12668-011-0032-3 · Cited by 157 · see citing works
Dopamine Modified Organic–Inorganic Hybrid Coating for Antimicrobial and Osteogenesis
Li, M., Liu, X., Xu, Z., Yeung, K. W. K., & Wu, S. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b09457 · Cited by 154 · see citing works
The Iron‐Fortified Adhesive System of Marine Mussels
Wilker, J. J. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201003171 · Cited by 134 · see citing works
Andersen, A., Krogsgaard, M., & Birkedal, H. (2017) · Biomacromolecules · doi:10.1021/acs.biomac.7b01249 · Cited by 132 · see citing works
Metallosupramolecular grid complexes: towards nanostructured materials with high-tech applications
Hardy, J. G. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60061k · Cited by 131 · see citing works
Lee, M. S., Lee, J. E., Byun, E., Kim, N. W., Lee, K., Lee, H., Sim, S. J., Lee, D. S., & Jeong, J. H. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.06.049 · Cited by 129 · see citing works
Inspiration from the natural world: from bio-adhesives to bio-inspired adhesives
Favi, P. M., Yi, S., Lenaghan, S. C., Xia, L., & Zhang, M. (2012) · Journal of Adhesion Science and Technology · doi:10.1080/01694243.2012.691809 · Cited by 126 · see citing works
Mussel-inspired transformation of CaCO3 to bone minerals
Kim, S., & Park, C. B. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.05.004 · Cited by 125 · see citing works
Dopamine-Induced Mineralization of Calcium Carbonate Vaterite Microspheres
Kim, S., & Park, C. B. (2010) · Langmuir · doi:10.1021/la1027509 · Cited by 125 · see citing works
Mussels as a Model System for Integrative Ecomechanics
Bell, E. C., Waite, J. H., Sarà, G., & Sebens, K. P. (2014) · Annual Review of Marine Science · doi:10.1146/annurev-marine-010213-135049 · Cited by 122 · see citing works
Self-citationLee, J., Chang, K., Kim, S., Gite, V., Chung, H., & Sohn, D. (2016) · Macromolecules · doi:10.1021/acs.macromol.6b01198 · Cited by 122 · see citing works
Marine bioinorganic materials: mussels pumping iron
Wilker, J. J. (2009) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2009.11.009 · Cited by 117 · see citing works
Krogsgaard, M., Hansen, M. R., & Birkedal, H. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb01503g · Cited by 115 · see citing works
Enabling Design of Advanced Elastomer with Bioinspired Metal–Oxygen Coordination
Zhang, X., Tang, Z., Guo, B., & Zhang, L. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b10881 · Cited by 114 · see citing works
Wu, C., Fan, W., Chang, J., & Xiao, Y. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm12770e · Cited by 109 · see citing works
Bio‐Inspired Synthesis of Minerals for Energy, Environment, and Medicinal Applications
Kim, S., & Park, C. B. (2012) · Advanced Functional Materials · doi:10.1002/adfm.201201994 · Cited by 109 · see citing works
Karabulut, E., Pettersson, T., Ankerfors, M., & Wågberg, L. (2012) · ACS Nano · doi:10.1021/nn204620j · Cited by 107 · see citing works
Douglas, T., Włodarczyk‐Biegun, M. K., Pamuła, E., Declercq, H., de Mulder, E., Bućko, M. M., Balcaen, L. I. L., Vanhaecke, F., Cornelissen, R., Dubruel, P., et al. (2012) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.1616 · Cited by 105 · see citing works
Yang, B., Lim, C., Hwang, D. S., & Chi, H. J. (2016) · Chemistry of Materials · doi:10.1021/acs.chemmater.6b03676 · Cited by 104 · see citing works
Lim, S., Park, T. Y., Jeon, E. Y., Joo, K. I., & Chi, H. J. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121171 · Cited by 100 · see citing works
Wear and abrasion resistance selection maps of biological materials
Amini, S., & Miserez, A. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.04.042 · Cited by 99 · see citing works
Polydopamine-Assisted Surface Modification for Bone Biosubstitutes
Huang, S., Liang, N., Hu, Y., Zhou, X., & Abidi, N. (2016) · BioMed Research International · doi:10.1155/2016/2389895 · Cited by 97 · see citing works
Mussel‐inspired biomaterials: From chemistry to clinic
Taghizadeh, A. A., Taghizadeh, M., Yazdi, M. K., Zarrintaj, P., Ramsey, J. D., Seidi, F., Stadler, F. J., Lee, H., Saeb, M. R., & Mozafari, M. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10385 · Cited by 96 · see citing works
Artificially Engineered Protein Polymers
Yang, Y. J., Holmberg, A. L., & Olsen, B. D. (2017) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-060816-101620 · Cited by 96 · see citing works
Mazrad, Z. A. I., Lee, K., Chae, A., In, I., Lee, H., & Park, S. Y. (2018) · Journal of Materials Chemistry B · doi:10.1039/c7tb03323k · Cited by 94 · see citing works
The Cross‐Linking Mechanism and Applications of Catechol–Metal Polymer Materials
Yan, G., Chen, G., Peng, Z., Shen, Z., Tang, X., Sun, Y. Q., Zeng, X., & Lin, L. (2021) · Advanced Materials Interfaces · doi:10.1002/admi.202100239 · Cited by 92 · see citing works
Bode, S., Enke, M., Bose, R. K., Schacher, F. H., García, S. J., van der Zwaag, S., Hager, M. D., & Schubert, U. S. (2015) · Journal of Materials Chemistry A · doi:10.1039/c5ta05545h · Cited by 90 · see citing works
Stiff Coatings on Compliant Biofibers: The Cuticle of Mytilus californianus Byssal Threads ,
Holten‐Andersen, N., Zhao, H., & Waite, J. H. (2009) · Biochemistry · doi:10.1021/bi900018m · Cited by 90 · see citing works
Self-citationKong, J., Shahabadi, S. I. S., & Lu, X. (2015) · Nanoscale · doi:10.1039/c5nr06711a · Cited by 90 · see citing works
Structural Interfaces and Attachments in Biology
Thomopoulos, S., Birman, V., & Genin, G. M. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3317-0 · Cited by 90 · see citing works
Kim, S., Moon, J., Choi, J. S., Cho, W. K., & Kang, S. M. (2016) · Advanced Functional Materials · doi:10.1002/adfm.201600613 · Cited by 87 · see citing works
Biological Materials Processing: Time-Tested Tricks for Sustainable Fiber Fabrication
Rising, A., & Harrington, M. J. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.2c00465 · Cited by 85 · see citing works
Zvarec, O., Purushotham, S., Mašić, A., Ramanujan, R. V., & Miserez, A. (2013) · Langmuir · doi:10.1021/la401858s · Cited by 84 · see citing works
Polydopamine films and particles with catalytic activity
Ball, V. (2017) · Catalysis Today · doi:10.1016/j.cattod.2017.01.031 · Cited by 81 · see citing works
Hwang, D. S., & Waite, J. H. (2012) · Protein Science · doi:10.1002/pro.2147 · Cited by 80 · see citing works
Self-citationNatural load-bearing protein materials
Harrington, M. J., & Fratzl, P. (2020) · Progress in Materials Science · doi:10.1016/j.pmatsci.2020.100767 · Cited by 80 · see citing works
Protein-mediated bioadhesion in marine organisms: A review
Li, X., Li, S., Huang, X., Chen, Y., Cheng, J., & Zhan, A. (2021) · Marine Environmental Research · doi:10.1016/j.marenvres.2021.105409 · Cited by 79 · see citing works
Kim, H. J., Yang, B., Park, T. Y., Lim, S., & Chi, H. J. (2017) · Soft Matter · doi:10.1039/c7sm01735a · Cited by 78 · see citing works
Tu, Q., Shen, X., Liu, Y., Zhang, Q., Zhao, X., Maitz, M. F., Liu, T., Qiu, H., Wang, J., Huang, N., et al. (2018) · Materials Chemistry Frontiers · doi:10.1039/c8qm00458g · Cited by 77 · see citing works
Bone-like peptide/hydroxyapatite nanocomposites assembled with multi-level hierarchical structures
Ryu, J., Ku, S. H., Lee, M., & Park, C. B. (2011) · Soft Matter · doi:10.1039/c1sm05307h · Cited by 77 · see citing works
Lee, B. P., Narkar, A. R., & Wilharm, R. K. (2015) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2015.12.038 · Cited by 77 · see citing works
Jehle, F., Macías‐Sánchez, E., Sviben, S., Fratzl, P., Bertinetti, L., & Harrington, M. J. (2020) · Nature Communications · doi:10.1038/s41467-020-14709-y · Cited by 76 · see citing works
Stability-enhanced polydopamine coatings on solid substrates by iron(III) coordination
Kim, S., Gim, T., & Kang, S. M. (2014) · Progress in Organic Coatings · doi:10.1016/j.porgcoat.2014.04.011 · Cited by 72 · see citing works
Bioinspired approaches for toughening of fibre reinforced polymer composites
Amorim, L., Santos, A., Nunes, J. P., & Viana, J. C. (2020) · Materials & Design · doi:10.1016/j.matdes.2020.109336 · Cited by 65 · see citing works
Reversible Layer‐by‐Layer Deposition on Solid Substrates Inspired by Mussel Byssus Cuticle
Kim, S., Kim, D.-S., & Kang, S. M. (2013) · Chemistry - An Asian Journal · doi:10.1002/asia.201301291 · Cited by 65 · see citing works
Kim, B. J., Kim, S., Oh, D. X., Mašić, A., Chi, H. J., & Hwang, D. S. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb01496k · Cited by 61 · see citing works
Polydopamine-assisted carbon nanotubes/Co3O4 composites for rechargeable Li-air batteries
Yoon, T. H., & Park, Y. J. (2013) · Journal of Power Sources · doi:10.1016/j.jpowsour.2013.01.023 · Cited by 60 · see citing works
Byssus Structure and Protein Composition in the Highly Invasive Fouling Mussel Limnoperna fortunei
Li, S., Xia, Z., Chen, Y., Gao, Y., & Zhan, A. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00418 · Cited by 60 · see citing works
Diverse Strategies of Protein Sclerotization in Marine Invertebrates
Rubin, D. J., Miserez, A., & Waite, J. H. (2010) · Advances in insect physiology · doi:10.1016/s0065-2806(10)38003-9 · Cited by 59 · see citing works
Self-citationSchmitt, C. N. Z., Winter, A., Bertinetti, L., Mašić, A., Strauch, P., & Harrington, M. J. (2015) · Journal of The Royal Society Interface · doi:10.1098/rsif.2015.0466 · Cited by 58 · see citing works
A biomimetic magnetically recoverable palladium nanocatalyst for the Suzuki cross-coupling reaction
Dubey, A. V., & Kumar, A. V. (2016) · RSC Advances · doi:10.1039/c6ra03395d · Cited by 57 · see citing works
Catechol-Vanadium Binding Enhances Cross-Linking and Mechanics of a Mussel Byssus Coating Protein
Mesko, M., Xiang, L., Bohle, D. S., Hwang, D. S., Zeng, H., & Harrington, M. J. (2021) · Chemistry of Materials · doi:10.1021/acs.chemmater.1c02063 · Cited by 56 · see citing works
Huang, P., Zeng, H., & Zeng, H. (2025) · Advanced Materials · doi:10.1002/adma.202501542 · Cited by 55 · see citing works
The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications
Bolaños‐Cardet, J., Pepió‐Tárrega, B., Saiz‐Poseu, J., López‐Moral, A., Ullah, F., Yuste, V. J., Ruiz‐Molina, D., & Suárez–García, S. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202513698 · Cited by 54 · see citing works
Cheng, J., Liu, H., Zhao, B., Shen, R., Liu, D., Hong, J., Wei, H. Y., Xi, P., Chen, F., & Bai, D. (2015) · Journal of Bioactive and Compatible Polymers · doi:10.1177/0883911515569918 · Cited by 54 · see citing works
Sacrificial Ionic Bonds Need To Be Randomly Distributed To Provide Shear Deformability
Hartmann, M. A., & Fratzl, P. (2009) · Nano Letters · doi:10.1021/nl901816s · Cited by 52 · see citing works
Glycosylated Hydroxytryptophan in a Mussel Adhesive Protein from Perna viridis
Zhao, H., Sagert, J. G., Hwang, D. S., & Waite, J. H. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.022517 · Cited by 52 · see citing works
Self-citationStabilized calcium phosphate nano-aggregates using a dopa-chitosan conjugate for gene delivery
Lee, K., Oh, M. H., Lee, M. S., Nam, Y. S., Park, T. G., & Jeong, J. H. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.01.014 · Cited by 49 · see citing works
Hydroxyapatite for Keratoprosthesis Biointegration
Wang, L., Jeong, K. J., Chiang, H. H., Zurakowski, D., Behlau, I., Chodosh, J., Dohlman, C. H., Langer, R., & Kohane, D. S. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.11-7601 · Cited by 48 · see citing works
Han, X., Tang, F., & Jin, Z. (2018) · RSC Advances · doi:10.1039/c8ra02930j · Cited by 48 · see citing works
Lee, Y. A., Lee, J., Kim, D., Yoo, C., Park, S. H., Yoo, J., Kim, S., Kim, B., Cho, W. K., & Yoon, H. (2017) · Journal of Materials Chemistry A · doi:10.1039/c7ta08010g · Cited by 46 · see citing works
Budisa, N., & Schneider, T. (2019) · ChemBioChem · doi:10.1002/cbic.201900030 · Cited by 40 · see citing works
Material-independent fabrication of superhydrophobic surfaces by mussel-inspired polydopamine
You, I., Seo, Y. C., & Lee, H. (2014) · RSC Advances · doi:10.1039/c3ra47626j · Cited by 44 · see citing works
Vidallon, M. L. P., Yu, F., & Teo, B. M. (2020) · Crystal Growth & Design · doi:10.1021/acs.cgd.9b01057 · Cited by 43 · see citing works
Li, S., Liu, C., Zhan, A., Xie, L., & Zhang, R. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.7b02132 · Cited by 42 · see citing works
Mussel-inspired healing of a strong and stiff polymer
Chen, N., Qin, L., & Pan, Q. (2018) · Journal of Materials Chemistry A · doi:10.1039/c8ta00760h · Cited by 42 · see citing works
Zhao, S., Wen, Y., Wang, Z., Kang, H., Li, J., Zhang, S., & Ji, Y. (2018) · Applied Surface Science · doi:10.1016/j.apsusc.2018.02.110 · Cited by 42 · see citing works
Maier, G. P., & Butler, A. (2017) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-017-1451-6 · Cited by 41 · see citing works
Mussel-Inspired Tough Double Network Hydrogel As Transparent Adhesive
Wang, X.-H., Si, Y., Zheng, K., Guo, X.-H., Wang, J., & Xu, Y.-S. (2019) · ACS Applied Polymer Materials · doi:10.1021/acsapm.9b00698 · Cited by 36 · see citing works
Braun, M., Menges, M., Opoku, F., & Smith, A. M. (2012) · Journal of Experimental Biology · doi:10.1242/jeb.077149 · Cited by 41 · see citing works
Marine hydroid perisarc: A chitin- and melanin-reinforced composite with DOPA–iron(III) complexes
Hwang, D. S., Mašić, A., Prajatelistia, E., Iordăchescu, M., & Waite, J. H. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.06.015 · Cited by 39 · see citing works
Self-citationMussel Coating Protein-Derived Complex Coacervates Mitigate Frictional Surface Damage
Miller, D. R., Das, S., Huang, K., Han, S., Israelachvili, J. N., & Waite, J. H. (2015) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5b00252 · Cited by 39 · see citing works
Self-citationImpact of open sea habitat on byssus attachment of suspension-cultured blue mussels (Mytilus edulis)
Heine, M.-O. S., Lachance, A.-A., Génard, B., Myrand, B., Pellerin, C., Marcotte, I., & Tremblay, R. (2014) · Aquaculture · doi:10.1016/j.aquaculture.2014.02.006 · Cited by 39 · see citing works
- Authors
- Holten-Andersen, N., Mates, T. E., Toprak, M. S., Stucky, G. D., Zok, F. W., & Waite, J. H.
- Affiliations
- Biomolecular Science and Engineering Program, Materials Department, and Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, California 93106
- University of California, Santa Barbara (US)
- Corresponding author
- Waite, J. Herbert
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-10-11
- Volume
- 25
- Issue
- 6
- Pages
- 3323-3326
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- PMC
- PMC2746015
- OpenAlex
- W2078630737
- Cited by
- 216
- References
- 35
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 8 · 2023: 12 · 2022: 11 · 2021: 15 · 2020: 14 · 2019: 11 · 2018: 12 · 2017: 15 · 2016: 12 · 2015: 15 · 2014: 14 · 2013: 17 · 2012: 14
- FWCI
- 4.97
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Langmuir (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of General Medical Sciences (R01GM065354, R01GM65354)
- National Institute of Dental and Craniofacial Research (R01DE018468, R01DE015415)
- Topics
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Physical Sciences › Engineering › Ocean Engineering › Marine Biology and Environmental Chemistry
- Physical Sciences › Materials Science › Biomaterials › Calcium Carbonate Crystallization and Inhibition
- Keywords
- cuticle, DOPA, metal chelation, iron, calcium, Mytilus galloprovincialis, cuticle integrity, composite coatings, natural adhesives, tensile deformation
- MeSH terms
- Animals, Biocompatible Materials, Biomechanical Phenomena, Calcium, Hydrogen-Ion Concentration, Iron, Levodopa, Metals, Microscopy, Electron, Scanning, Microscopy, Fluorescence, Models, Chemical, Surface Properties, Microscopy, Electron, Transmission, Bivalvia, Mytilus
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
