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End-capped α-helices as modulators of protein function

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Proline primed helix length as a modulator of the nuclear receptor-coactivator interaction

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Synthesis and screening of small-molecule α-helix mimetic libraries targeting protein–protein interactions

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Broad Distribution of Energetically Important Contacts across an Extended Protein Interface

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From Concepts to Inhibitors: A Blueprint for Targeting Protein–Protein Interactions

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Neue Modalitäten für schwierige Zielstrukturen in der Wirkstoffentwicklung

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Foldamers in Medicinal Chemistry

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HippDB: a database of readily targeted helical protein–protein interactions

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Efficient α‐Helix Induction in a Linear Peptide Chain by N ‐Capping with a Bridged‐tricyclic Diproline Analogue

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Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale

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Deregulations in the Cyclin-Dependent Kinase-9-Related Pathway in Cancer: Implications for Drug Discovery and Development

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Understanding and designing head‐to‐tail cyclic peptides

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Cyclisation strategies for stabilising peptides with irregular conformations

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An Anthraquinone Scaffold for Putative, Two-Face Bim BH3 α-Helix Mimic

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Protein–protein interactions in transcription: A fertile ground for helix mimetics

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Oxime Side‐Chain Cross‐Links in an α‐Helical Coiled‐Coil Protein: Structure, Thermodynamics, and Folding‐Templated Synthesis of Bicyclic Species

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Protein-Protein Interactions and Aggregation Inhibitors in Alzheimer’s Disease

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The oncogenic potential of small nuclear ribonucleoprotein polypeptide G: a comprehensive and perspective view.

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The effect of azobenzene cross-linker position on the degree of helical peptide photo-control

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Foldamers as Anticancer Therapeutics: Targeting Protein–Protein Interactions and the Cell Membrane

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A Modular Synthesis of Teraryl‐Based α‐Helix Mimetics, Part 2: Synthesis of 5‐Pyridine Boronic Acid Pinacol Ester Building Blocks with Amino Acid Side Chains in 3‐Position

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Chiral Sulfoxide-Induced Single Turn Peptide α-Helicity

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A new strategy for the in vitro selection of stapled peptide inhibitors by mRNA display

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Peptide Inhibitors of Viral Assembly: A Novel Route to Broad-Spectrum Antivirals

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Benzimidazole-2-one: A novel anchoring principle for antagonizing p53-Mdm2

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Peptide Tethering: Pocket-Directed Fragment Screening for Peptidomimetic Inhibitor Discovery

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Synthesis of a Tetrasubstituted Tetrahydronaphthalene Scaffold for α-Helix Mimicry via a MgBr2-Catalyzed Friedel–Crafts Epoxide Cycloalkylation

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Synthetic helical peptide capping strategies

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An optimal hydrogen-bond surrogate for α-helices

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Synthesis of Hydrogen‐Bond Surrogate α‐Helices as Inhibitors of Protein‐Protein Interactions

Miller, S. E., Thomson, P. F., & Arora, P. S. (2014) · Current Protocols in Chemical Biology · doi:10.1002/9780470559277.ch130202 · Cited by 17 · see citing works

Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide

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Peptide‐Directed Binding for the Discovery of Modulators of α‐Helix‐Mediated Protein–Protein Interactions: Proof‐of‐Concept Studies with the Apoptosis Regulator Mcl‐1

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Aromatic Foldamer Helices as α‐Helix Extended Surface Mimetics

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Backbone thioamide directed macrocyclisation: lactam stapling of peptides

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8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction

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De Novo Hydrocarbon-Stapling Design of Single-Turn α-Helical Antimicrobial Peptides

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Design and Synthesis of a Prototype Scaffold for Five‐Residue α‐Helix Mimetics

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Stapled peptides: targeting protein-protein interactions in drug development

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Library Construction, Selection and Modification Strategies to Generate Therapeutic Peptide-Based Modulators of Protein–Protein Interactions

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Assessing Helical Protein Interfaces for Inhibitor Design

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Assessment of helical interfaces in protein–protein interactions

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Comprehensive analysis of loops at protein-protein interfaces for macrocycle design

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Protein Surface Recognition by Synthetic Molecules

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Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces

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