Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology

Selenium: Biochemical Role as a Component of Glutathione Peroxidase

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NITRIC OXIDE: A Physiologic Messenger Molecule

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THIOREDOXIN

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SELENIUM AS AN INTEGRAL PART OF FACTOR 3 AGAINST DIETARY NECROTIC LIVER DEGENERATION

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Chemistry of Biologically Important Synthetic Organoselenium Compounds

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A SIMPLE PREPARATION OF ADAMANTANE

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Neurodegenerative diseases and oxidative stress

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Enzymatic Synthesis of Deoxyribonucleotides

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Nitric Oxide: Pathophysiological Mechanisms

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Selenium reagents and intermediates in organic synthesis

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[5] Diversity of glutathione peroxidases

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A novel biologically active seleno-organic compound—1

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Palladium catalyzed synthesis of aryl, heterocyclic and vinylic acetylene derivatives

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Lessons from Basic Research in Selenium and Cancer Prevention

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Chemopreventive Agents

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Synthetic organoselenium compounds as antioxidants: glutathione peroxidase activity

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On the nature of selenium toxicity and carcinostatic activity

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Ebselen in Acute Ischemic Stroke: A Placebo-Controlled, Double-blind Clinical Trial

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Selenium in Biology and Medicine

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Identification of the catalytic site of rat liver glutathione peroxidase as selenocysteine

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Nucleophilic reactivity constants toward methyl iodide and trans-dichlorodi(pyridine)platinum(II)

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Diphenyl Diselenide and Ascorbic Acid Changes Deposition of Selenium and Ascorbic Acid in Liver and Brain of Mice

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A novel biologically active seleno-organic compound—II

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Ebselen, a selenoorganic compound as glutathione peroxidase mimic

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Molecular actions of Ebselen—an antiinflammatory antioxidant

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Development of synthetic compounds with glutathione peroxidase activity

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Purification and characterization of human plasma glutathione peroxidase: A selenoglycoprotein distinct from the known cellular enzyme

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The role of selenium peroxidases in the protection against oxidative damage of membranes

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Essentiality and toxicity of selenium and its status in Australia: a review

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Functional group manipulation using organoselenium reagents

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Doxorubicin-induced Apoptosis in Endothelial Cells and Cardiomyocytes Is Ameliorated by Nitrone Spin Traps and Ebselen

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The Chemistry and Toxicity of Selenium Compounds, with Special Reference to the Selenium Problem.

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The protective role of selenium on genetic damage and on cancer

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A Model Study on the Effect of an Amino Group on the Antioxidant Activity of Glutathione Peroxidase

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Selenotrisulfides. Formation by the reaction of thiols with selenious acid

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Reduction of the selenotrisulfide derivative of glutathione to a persulfide analog by gluthathione reductase

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Biomethylation of selenium and tellurium: microorganisms and plants

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Glutathione Peroxidase-like Antioxidant Activity of Diaryl Diselenides: A Mechanistic Study

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The biochemistry of selenium and the glutathione system

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Biochemistry of Selenium

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Possible protective effect of selenium against human cancer.

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Neuroprotective Effect of an Antioxidant, Ebselen, in Patients with Delayed Neurological Deficits after Aneurysmal Subarachnoid Hemorrhage

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Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant

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Selenium dioxide oxidation of olefins. Evidence for the intermediacy of allylseleninic acids

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Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non‐stoichiometric oxidation of NADPH in the presence of oxygen

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Anti-inflammatory and antinociceptive activity of diphenyl diselenide

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Molecular Biology of Selenoproteins

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An analysis of cancer prevention by selenium

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Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase.

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Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells

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Antioxidant Properties of New Chalcogenides Against Lipid Peroxidation in Rat Brain

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Thioredoxin, a putative oncogene product,is overexpressed in gastric carcinoma and associated with increased proliferation and increased cell survival

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Thiol peroxidase activity of diaryl ditellurides as determined by a proton NMR method

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A new immunomodulating compound (AS-101) with potential therapeutic application

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Heteroatom-Directed Aromatic Lithiation: A Versatile Route to the Synthesis of Organochalcogen (Se, Te) Compounds

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Effect of Organic Forms of Selenium on δ-Aminolevulinate Dehydratase from Liver, Kidney, and Brain of Adult Rats

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Acid-volatile selenium formation catalyzed by glutathione reductase

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A Novel Antioxidant Mechanism of Ebselen Involving Ebselen Diselenide, a Substrate of Mammalian Thioredoxin and Thioredoxin Reductase

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A Novel Camphor-Derived Selenenamide That Acts as a Glutathione Peroxidase Mimetic

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Cloning and Functional Characterization of Human Selenophosphate Synthetase, an Essential Component of Selenoprotein Synthesis

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Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice

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Biochemistry of tellurium

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A New Toxicant Occurring Naturally in Certain Samples of Plant Foodstuffs

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New Concepts in Selenium Chemoprevention

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Kinetic study of the reaction of ebselen with peroxynitrite

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The Reaction of Ebselen with Peroxynitrite

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Risk biomarkers and current strategies for cancer chemoprevention

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Catalytic Oxidation of Glutathione and Other Sulfhydryl Compounds by Selenite

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Lead poisoning, haem synthesis and 5-aminolaevulinic acid dehydratase

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New organoselenium methodology

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Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51)

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Neuroprotective efficacy of ebselen, an anti‐oxidant with anti‐inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion

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Comparison of selenium and sulfur analogs in cancer prevention

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Porphobilinogen synthase, the first source of Heme's asymmetry

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Dissociation of the genotoxic and growth inhibitory effects of selenium

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Mechanism of the Catalytic Reduction of Hydroperoxides by Ebselen : A Selenium ‐ 77 Nmr Study

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Glutathione oxidase activity of selenocystamine: A mechanistic study

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Cell growth stimulation by the redox protein thioredoxin occurs by a novel helper mechanism.

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The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat

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The role of zinc with special reference to the essential thiol groups in δ-aminolevulinic acid dehydratase of bovine liver

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A novel biologically active seleno-organic compound—III

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The Antioxidant Profile of 2,3-Dihydrobenzo[b]furan-5-ol and Its 1-Thio, 1-Seleno, and 1-Telluro Analogues

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The Two Faces of Selenium

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Studies on the anti-inflammatory activity of ebselen

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Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo

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Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation

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Ebselen prevents early alcohol-induced liver injury in rats

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α‐Phenylseleno‐methyllithiumverbindungen

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Enzymic Synthesis of Dimethyl Selenide from Sodium Selenite in Mouse Liver Extracts*

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Chemical transformations of selenium in living organisms. Improved forms of selenium for cancer prevention

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EXCRETION OF DIMETHYL SELENIDE BY THE RAT

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Biosynthesis of dimethyl selenide from sodium selenite in rat liver and kidney cell-free systems

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Selenium-Containing Compounds Protect DNA fromSingle-Strand Breaks Caused by Peroxynitrite

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Mechanism of the reaction of ebselen with endogenous thiols: dihydrolipoate is a better cofactor than glutathione in the peroxidase activity of ebselen.

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Molecular Mechanisms of Cancer Prevention by Selenium Compounds

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Glutathione Peroxidase-like Activities of Oxygen-Containing Diselenides

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Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons

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Ebselen blocks the quinolinic acid-induced production of thiobarbituric acid reactive species but does not prevent the behavioral alterations produced by intra-striatal quinolinic acid administration in the rat

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The Antioxidant Ebselen Prevents Neurotoxicity and Clinical Symptoms in a Primate Model of Parkinson's Disease

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A novel biologically active seleno-organic compound—VI

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Ebselen Induces Apoptosis in HepG2 Cells through Rapid Depletion of Intracellular Thiols

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Chemoprevention of cancer by organoselenium compounds

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Benzoselenazolinone Derivatives Designed To Be Glutathione Peroxidase Mimetics Feature Inhibition of Cyclooxygenase/5-Lipoxygenase Pathways and Anti-inflammatory Activity

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Toxicity of Dimethyl Selenide in the Rat and Mouse

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Comparative effect of inorganic and organic selenocyanate derivatives in mammary cancer chemoprevention

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Antioxidant Regulation of Protein Kinase C in Cancer Prevention

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Inhibition of Superoxide and Nitric Oxide Release and Protection From Reoxygenation Injury by Ebselen in Rat Kupffer Cells

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Action of ebselen as an antioxidant against lipid peroxidation

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Mechanism of porphobilinogen synthase. Possible role of essential thiol groups.

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