Modulators of Protein–Protein Interactions

Cited by (523)

Items 201–300 of 523

1. Harnessing the 14-3-3 protein–protein interaction network
   Paulo Pitasse-Santos, Isaac Hewitt-Richards, Malsha D. Abeywickrama Wijewardana Sooriyaarachchi, Richard G. Doveston · 2024 · Current Opinion in Structural Biology
2. A comprehensive in vitro fluorescence anisotropy assay system for screening ligands of the jasmonate COI1–JAZ co-receptor in plants
   Yousuke Takaoka, Keina Nagumo, Ika Nurul Azizah, Saki Oura, Mana Iwahashi, Nobuki Kato, Minoru Ueda · 2019 · Journal of Biological Chemistry
3. Targeted Protein Localization by Covalent 14–3–3 Recruitment
   Qian Shao, Tuong Nghi Duong, Inji Park, Lauren M. Orr, Daniel K. Nomura · 2024 · Journal of the American Chemical Society
4. Solid‐Phase Synthesis of Peptidomimetics with Peptide Backbone Modifications
   Aizhan Abdildinova, Mark J. Kurth, Young‐Dae Gong · 2021 · Asian Journal of Organic Chemistry
5. DLiP-PPI library: An integrated chemical database of small-to-medium-sized molecules targeting protein–protein interactions
   Kazuyoshi Ikeda, Yuta Maezawa, Tomoki Yonezawa, Yugo Shimizu, Toshiyuki Tashiro, Satoru Kanai, Nobuyoshi Sugaya, Yoshiaki Masuda, Naoko Inoue, Tatsuya Niimi et al. · 2023 · Frontiers in Chemistry
6. The Potential of Peptide-Based Inhibitors in Disrupting Protein–Protein Interactions for Targeted Cancer Therapy
   Alexandra L. Afonso, Catarina T. Cavaleiro, Miguel A. R. B. Castanho, Vera Neves, Marco Calvinho Cavaco · 2025 · International Journal of Molecular Sciences
7. Influence of side-chain interactions on the self-assembly of discotic tricarboxyamides: a crystallographic insight
   Arpita Paikar, Apurba Pramanik, Debasish Haldar · 2015 · RSC Advances
8. Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1
   May Bakail, Albane Gaubert, Jessica Andréani, Gwénaëlle Moal, Guillaume Pinna, Ekaterina Boyarchuk, Marie-Cécile Gaillard, Régis Courbeyrette, Carl Mann, Jean‐Yves Thuret et al. · 2019 · Cell chemical biology
9. Supramolecular Enhancement of a Natural 14–3–3 Protein Ligand
   X. Guillory, Inesa Hadrović, Pim J. de Vink, Andrea Sowislok, Luc Brunsveld, Thomas H. Schrader, Christian Ottmann · 2021 · Journal of the American Chemical Society
10. Supramolecular protection from the enzymatic tyrosine phosphorylation in a polypeptide
    Enrico Faggi, Yolanda Pérez, Santiago V. Luis, Ignacio Alfonso · 2016 · Chemical Communications
11. Set-up and screening of a fragment library targeting the 14-3-3 protein interface
    Dario Valenti, João Filipe Neves, François‐Xavier Cantrelle, Stanimira Hristeva, Domenico Lentini Santo, Tomáš Obšil, Xavier Hanoulle, Laura M. Levy, Dimitrios Tzalis, Isabelle Landrieu et al. · 2019 · MedChemComm
12. Does the protein corona take over the selectivity of molecularly imprinted nanoparticles? The biological challenges to recognition
    Anna Laura Capriotti, Susy Piovesana, Riccardo Zenezini Chiozzi, Carmela Maria Montone, Alessandra Bossi, Aldo Laganà · 2020 · Journal of Proteomics
13. Tyrosinase‐Catalyzed Peptide Stapling Using Para‐Amino Phenylalanine and Tyrosine Anchoring Residues
    Nan Wang, Zhengyang Xu, Huaxing Shen, Wei Cong, Shuai Zhang, Honggang Hu, Xiang Li · 2025 · Angewandte Chemie International Edition
14. Stafia‐1: a STAT5a‐Selective Inhibitor Developed via Docking‐Based Screening of in Silico O‐Phosphorylated Fragments
    Kalaiselvi Natarajan, Daniel Müller‐Klieser, Stefan Rubner, Thorsten Berg · 2019 · Chemistry - A European Journal
15. Small‐Molecule‐Induced and Cooperative Enzyme Assembly on a 14‐3‐3 Scaffold
    Anniek den Hamer, Lenne J. M. Lemmens, Minke A. D. Nijenhuis, Christian Ottmann, Maarten Merkx, Tom F. A. de Greef, Luc Brunsveld · 2016 · ChemBioChem
16. An in-tether chiral center modulates the proapoptotic activity of the KLA peptide
    Jingxu Li, Kuan Hu, Hailing Chen, Yujie Wu, Longjian Chen, Feng Yin, Yuan Tian, Zigang Li · 2017 · Chemical Communications
17. A reversible fluorescent probe for directly monitoring protein-small molecules interaction utilizing vibration-induced emission
    Na Wang, Chenqi Xin, Zheng Li, Gaobin Zhang, Lei Bai, Qiuyu Gong, Chenchen Xu, Han Xu, Changmin Yu, Lin Li et al. · 2018 · Dyes and Pigments
18. Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers
    Eline Sijbesma, Kenneth K. Hallenbeck, Sebastian A. Andrei, Reanne R. Rust, Joris M. C. Adriaans, Luc Brunsveld, Michelle R. Arkin, Christian Ottmann · 2021 · ACS Medicinal Chemistry Letters
19. Developing Small-Molecule Inhibitors of Protein-Protein Interactions Involved in Viral Entry as Potential Antivirals for COVID-19
    Péter Buchwald · 2022 · Frontiers in Drug Discovery
20. Medicinal Chemistry Approaches to Heart Regeneration
    Dennis Schade, Alleyn T. Plowright · 2015 · Journal of Medicinal Chemistry
21. Optimization and bioevaluation of Cdc37-derived peptides: An insight into Hsp90-Cdc37 protein-protein interaction modulators
    Lei Wang, Li Li, Weitao Fu, Zhengyu Jiang, Qidong You, Xiaoli Xu · 2016 · Bioorganic & Medicinal Chemistry
22. A chiral interpenetrating polymer network constructed by helical substituted polyacetylenes and used for glucose adsorption
    Junya Liang, Jianping Deng · 2017 · Polymer Chemistry
23. Rational Design, Binding Studies, and Crystal‐Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14‐3‐3ζ Adapter Protein
    Martin Ehlers, Jean‐Noël Grad, Sumit Mittal, David Bier, Marcel Mertel, Ludwig Ohl, Maria Bartel, Jeroen M. Briels, Marius Heimann, Christian Ottmann et al. · 2017 · ChemBioChem
24. Methylene Blue Is a Nonspecific Protein–Protein Interaction Inhibitor with Potential for Repurposing as an Antiviral for COVID-19
    Sung-Ting Chuang, Henrietta Papp, Anett Kuczmog, Rebecca Eells, José Manuel Cóndor Capcha, Lina A. Shehadeh, Ferenc Jakab, Péter Buchwald · 2022 · Pharmaceuticals
25. Construction of piperidine-2,4-dione-type azaheterocycles and their application in modern drug development and natural product synthesis
    Rabdan M. Tikhov, Nikolai Yu. Kuznetsov · 2020 · Organic & Biomolecular Chemistry
26. Development and therapeutic potential of GSPT1 molecular glue degraders: A medicinal chemistry perspective
    Xiujin Chang, Fangui Qu, Chunxiao Li, Jingtian Zhang, Yanqing Zhang, Yuanyuan Xie, Zhongpeng Fan, Jinlei Bian, Jubo Wang, Zhiyu Li et al. · 2024 · Medicinal Research Reviews
27. Development of photoaffinity derivatives of the antitumor macrolide aplyronine A, a PPI-inducer between actin and tubulin
    Masaki Kita, Kota Yamagishi, Kota Tsuchiya, Yu Seguchi, Hiroki Nakane, Hideo Kigoshi · 2017 · Bioorganic & Medicinal Chemistry
28. Design and synthesis of a DNA-encoded combinatorial library of bicyclic peptoids
    KangJu Lee, Geul Bang, Yong Wook Kim, Min Hyeon Shin, Hyun‐Suk Lim · 2021 · Bioorganic & Medicinal Chemistry
29. Methods for the Discovery and Identification of Small Molecules Targeting Oxidative Stress-Related Protein–Protein Interactions: An Update
    Xuexuan Wu, Qiuyue Zhang, Yuqi Guo, Hengheng Zhang, Xiaoke Guo, Qidong You, Lei Wang · 2022 · Antioxidants
30. Synthetic helical peptide capping strategies
    Jonathan Whisenant, Kevin Burgess · 2022 · Chemical Society Reviews
31. Small-Molecule Inhibitors of Protein–Protein Interactions
    Zhihong Liu, H. Chen, Eric A. Wold, Jia Zhou · 2016 · Elsevier eBooks
32. Macrocyclic Compounds from Ansamycin Antibiotic Class as Inhibitors of PD1–PDL1 Protein–Protein Interaction
    Sachin P. Patil, Suk-Chung Yoon, Abhay G. Aradhya, Jeremy Hofer, Madison A. Fink, Erika S. Enley, James E. Fisher, Marie C. Herb, Anthony Klingos, James T. Proulx et al. · 2018 · Chemical and Pharmaceutical Bulletin
33. Cyclic Tau-derived peptides for stabilization of microtubules
    Hiroshi Inaba, Miyuu Nagata, Kyeongmi Juliano Miyake, Arif Md. Rashedul Kabir, Akira Kakugo, Kazuki Sada, Kazunori Matsuura · 2020 · Polymer Journal
34. Atomic Details of Carbon-Based Nanomolecules Interacting with Proteins
    Luigi Di Costanzo, Silvano Geremia · 2020 · Molecules
35. Multivalent helix mimetics for PPI-inhibition
    Anna Barnard, Jennifer A. Miles, George M. Burslem, Amy Barker, Andrew John Wilson · 2014 · Organic & Biomolecular Chemistry
36. Computational Tools and Strategies to Develop Peptide-Based Inhibitors of Protein-Protein Interactions
    Maxence Delaunay, Tâp Ha‐Duong · 2021 · Methods in molecular biology
37. DNA Mimic Foldamer Recognition of a Chromosomal Protein
    Deepak Deepak, Jiaojiao Wu, Valentina Corvaglia, Lars Allmendinger, Michael Scheckenbach, Philip Tinnefeld, Ivan Huc · 2024 · Angewandte Chemie International Edition
38. MicroScale Thermophoresis as a Tool to Study Protein-peptide Interactions in the Context of Large Eukaryotic Protein Complexes
    Maximilian G. Plach, Klaus D. Grasser, Thomas E. O. Schubert · 2017 · BIO-PROTOCOL
39. A biophysical and structural analysis of the interaction of BLNK with 14-3-3 proteins
    Lorenzo Soini, S. Leysen, Jeremy Davis, Christian Ottmann · 2020 · Journal of Structural Biology
40. New Tools to Probe the Protein Surface: Ultrasmall Gold Nanoparticles Carry Amino Acid Binders
    Selina Beatrice van der Meer, Inesa Hadrović, Annika Meiners, Kateryna Loza, Marc Heggen, Shirley K. Knauer, Peter Bayer, Thomas H. Schrader, Christine Beuck, Matthias Epple · 2020 · The Journal of Physical Chemistry B
41. Query-guided protein–protein interaction inhibitor discovery
    Sergio Celis, Fruzsina Hóbor, Thomas James, Gail J. Bartlett, Amaurys Ávila Ibarra, Deborah K. Shoemark, Zsófia Hegedüs, Kristina Hetherington, Derek N. Woolfson, Richard Barry Sessions et al. · 2021 · Chemical Science
42. Protein Surface Mimetics: Understanding How Ruthenium Tris(Bipyridines) Interact with Proteins
    Sarah H. Hewitt, Maria H. Filby, Ed Hayes, Lars T. Kuhn, Arnout P. Kalverda, Michael E. Webb, Andrew John Wilson · 2016 · ChemBioChem
43. Molecular tweezers target a protein–protein interface and thereby modulate complex formation
    Franziska Trusch, Klaus Kowski, Kenny Bravo‐Rodriguez, Christine Beuck, Andrea Sowislok, Burkhard Wettig, Anja Matena, Elsa Sánchez‐García, Hemmo H Meyer, Thomas H. Schrader et al. · 2016 · Chemical Communications
44. PIIMS Server: A Web Server for Mutation Hotspot Scanning at the Protein–Protein Interface
    Fengxu Wu, Jing‐Fang Yang, Long‐Can Mei, Fan Wang, Ge‐Fei Hao, Guang‐Fu Yang · 2021 · Journal of Chemical Information and Modeling
45. Application of Nanopore Sensors for Biomolecular Interactions and Drug Discovery
    Ki‐Baek Jeong, Jin‐Sik Kim, Naresh Niranjan Dhanasekar, Mi‐Kyung Lee, Seung‐Wook Chi · 2022 · Chemistry - An Asian Journal
46. Activity‐Directed Synthesis of Inhibitors of the p53/ h DM2 Protein–Protein Interaction
    Adam I. Green, Fruzsina Hóbor, Christopher P. Tinworth, Stuart L. Warriner, Andrew John Wilson, Adam S. Nelson · 2020 · Chemistry - A European Journal
47. Noncellular screening for the discovery of protein–protein interaction modulators
    Charline Kieffer, Jean‐Pierre Jourdan, Marie Jouanne, Anne Sophie Voisin‐Chiret · 2020 · Drug Discovery Today
48. Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐xL and MCL‐1 through Noncanonical Structural Motifs**
    Jennifer A. Miles, Fruzsina Hóbor, Chi H. Trinh, James Ward Taylor, Christian Tiede, Philip R. Rowell, Brian R. Jackson, Fatima Nadat, Pallavi Ramsahye, Hannah F. Kyle et al. · 2020 · ChemBioChem
49. Recognition-induced covalent capturing and labeling as a general strategy for protein detection
    Hao Li, Yue Huang, Yue Yu, Yao Wang, Genxi Li · 2016 · Biosensors and Bioelectronics
50. Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups
    George M. Burslem, Hannah F. Kyle, Panchami Prabhakaran, Alexander L. Breeze, Thomas A. Edwards, Stuart L. Warriner, Adam S. Nelson, Andrew John Wilson · 2016 · Organic & Biomolecular Chemistry
51. N-Difluoromethyl-triazole as a constrained scaffold in peptidomimetics
    Marius Mamone, Raoni S. B. Gonçalves, Florent Blanchard, Guillaume Bernadat, Sandrine Ongeri, Thierry Milcent, Benoı̂t Crousse · 2017 · Chemical Communications
52. Applications of in Silico Methods for Design and Development of Drugs Targeting Protein-Protein Interactions
    Vittoria Cicaloni, Alfonso Trezza, Francesco Pettini, Ottavia Spiga · 2019 · Current Topics in Medicinal Chemistry
53. Statistical Thermodynamics for Actin-Myosin Binding: The Crucial Importance of Hydration Effects
    Hiraku Oshima, Tomohiko Hayashi, Masahiro Kinoshita · 2016 · Biophysical Journal
54. A Peptide-Based Ligand-Directed Chemistry Enables Protein Functionalization
    Yuena Wang, Rongtong Zhao, Chuan Wan, Xiaochun Guo, Fenfang Yang, Zhanfeng Hou, Rui Ying Wang, Shuiming Li, Tiejian Feng, Feng Yin et al. · 2022 · Organic Letters
55. Selected Approaches to Disrupting Protein–Protein Interactions within the MAPK/RAS Pathway
    Stephen J. Harwood, Christopher R. Smith, J. David Lawson, John M. Ketcham · 2023 · International Journal of Molecular Sciences
56. Cyclobutane-bearing restricted anchoring residues enabled geometry-specific hydrocarbon peptide stapling
    Baobao Chen, Chao Liu, Wei Cong, Fei Gao, Yan Zou, Li Su, Lei Liu, Alexander Hillisch, Lutz Eric Lehmann, Donald E. Bierer et al. · 2023 · Chemical Science
57. Identification of Small‐Molecule Inhibitors of the Antiapoptotic Protein Myeloid Cell Leukaemia‐1 (Mcl‐1)
    Andrew Michael Beekman, Maria Anne O'Connell, Lesley A. Howell · 2015 · ChemMedChem
58. Analysis of the aplyronine A-induced protein–protein interaction between actin and tubulin by surface plasmon resonance
    Yuichiro Hirayama, Kota Yamagishi, Tomohiro Suzuki, Hirokazu Kawagishi, Masaki Kita, Hideo Kigoshi · 2016 · Bioorganic & Medicinal Chemistry
59. Improving cell penetration of helical peptides stabilized by N-terminal crosslinked aspartic acids
    Hui Zhao, Yan‐Hong Jiang, Yuan Tian, Dan Yang, Xuan Qin, Zigang Li · 2016 · Organic & Biomolecular Chemistry
60. Identification of Small‐Molecule Inhibitors of PD‐1/PD‐L1 Protein‐Protein Interaction
    Sachin P. Patil, Madison A. Fink, Erika S. Enley, James E. Fisher, Marie C. Herb, Anthony Klingos, James T. Proulx, Megan T. Fedorky · 2018 · ChemistrySelect
61. Systematic ‘foldamerization’ of peptide inhibiting p53-MDM2/X interactions by the incorporation of trans- or cis-2-aminocyclopentanecarboxylic acid residues
    Paulina Fortuna, Aleksandra Twarda‐Clapa, Łukasz Skalniak, Katarzyna Ożga, Tad A. Holak, Łukasz Berlicki · 2020 · European Journal of Medicinal Chemistry
62. ProPairs: A Data Set for Protein–Protein Docking
    Florian Krull, Gerrit Korff, Nadia Elghobashi‐Meinhardt, Ernst‐Walter Knapp · 2015 · Journal of Chemical Information and Modeling
63. Rational design of a sensitivity-enhanced tracer for discovering efficient APC–Asef inhibitors
    Jie Zhong, Yuegui Guo, Shaoyong Lu, Kun Song, Ying Wang, Li Feng, Zhen Zheng, Qiufen Zhang, Jiacheng Wei, Peng Sang et al. · 2022 · Nature Communications
64. Apoptosis Inhibitor 5: A Multifaceted Regulator of Cell Fate
    Hafsia Abbas, Dalia Kheira Derkaoui, Louise Jeammet, Emilie Adicéam, Jérôme Tiollier, Hélène Sicard, Thorsten Braun, Jean‐Luc Poyet · 2024 · Biomolecules
65. Peptide‐Directed Binding for the Discovery of Modulators of α‐Helix‐Mediated Protein–Protein Interactions: Proof‐of‐Concept Studies with the Apoptosis Regulator Mcl‐1
    Andrew Michael Beekman, Maria Anne O'Connell, Lesley A. Howell · 2017 · Angewandte Chemie International Edition
66. Aromatic Foldamer Helices as α‐Helix Extended Surface Mimetics
    Márton Zwillinger, Post Sai Reddy, Barbara Wicher, Pradeep K. Mandal, Márton Csékei, Lucile Fischer, András Kotschy, Ivan Huc · 2020 · Chemistry - A European Journal
67. Medicinal Chemistry Strategies for the Development of Inhibitors Disrupting β-Catenin’s Interactions with Its Nuclear Partners
    Hao Zhang, Chenglong Liu, Di Zhu, Qingwei Zhang, Jianqi Li · 2022 · Journal of Medicinal Chemistry
68. Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction
    Mariell Pettersson, Maria Quant, Jaeki Min, Luigi I. Iconaru, Richard W. Kriwacki, Michael Brett Waddell, Rodney Kiplin Guy, Kristina Luthman, Morten Grøtli · 2015 · PLoS ONE
69. Interacting partners of FEN1 and its role in the development of anticancer therapeutics
    Chandrasekhar Kathera, Jing Zhang, Avilala Janardhan, Hongfang Sun, Wajid Ali, Xiaolong Zhou, Lingfeng He, Zhigang Guo · 2017 · Oncotarget
70. Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40–CD154 Costimulatory Protein-Protein Interaction
    Damir Bojadzic, Jinshui Chen, Oscar Alcazar, Péter Buchwald · 2018 · Molecules
71. Recent advances in peptidomimetics antagonists targeting estrogen receptor α-coactivator interaction in cancer therapy
    Weirong Qin, Mingsheng Xie, Xuan Qin, Qi Fang, Feng Yin, Zigang Li · 2018 · Bioorganic & Medicinal Chemistry Letters
72. Stapled peptides: targeting protein-protein interactions in drug development
    Qian Zhang, Ziyang Wang, Xiaohan Mei, Quan Chen, Chunqiu Zhang · 2024 · Exploration of Drug Science
73. Benchmark Study Based on 2P2IDB to Gain Insights into the Discovery of Small-Molecule PPI Inhibitors
    Zhe Wang, Yu Kang, Dan Li, Huiyong Sun, Xiaowu Dong, Xiaojun Yao, Lei Xu, Shan Chang, Youyong Li, Tingjun Hou · 2018 · The Journal of Physical Chemistry B
74. Lights, Camera, Interaction: Studying Protein–Protein Interactions of the ER Protein Translocase in Living Cells
    Mark Sicking, Martin Jung, Sven Lang · 2021 · International Journal of Molecular Sciences
75. Fragment-based exploration of the 14-3-3/Amot-p130 interface
    Federica Centorrino, Blaž Andlovic, Peter J. Cossar, Luc Brunsveld, Christian Ottmann · 2021 · Current Research in Structural Biology
76. Strategies and Applications for Supramolecular Protein Self‐Assembly
    Yijia Li, Ruizhen Tian, Yingping Zou, Tingting Wang, Junqiu Liu · 2024 · Chemistry - A European Journal
77. Analysis of Interactions Stabilized by Fusicoccin A Reveals an Expanded Suite of Potential 14–3–3 Binding Partners
    Ananya Sengupta, Josue Liriano, Brian G. Miller, James H. Frederich · 2020 · ACS Chemical Biology
78. Structure – Bioactivity Relationship in Cyclic Peptoids: An Overview
    Assunta D’Amato · 2022 · European Journal of Organic Chemistry
79. Prediction and integration of metabolite-protein interactions with genome-scale metabolic models
    Mahdis Habibpour, Zahra Razaghi‐Moghadam, Zoran Nikoloski · 2024 · Metabolic Engineering
80. An in-tether sulfoxide chiral center influences the biophysical properties of the N-capped peptides
    Jingxu Li, Yuan Tian, Dongyuan Wang, Yujie Wu, Xiyang Ye, Zigang Li · 2016 · Bioorganic & Medicinal Chemistry
81. PROTAC: A Novel Technology for Drug Development**
    Jie Li, Jie‐Qing Liu · 2020 · ChemistrySelect
82. Understanding of the Effects of Ionic Strength on the Bimolecular Rate Constant between Structurally Identified Redox Enzymes and Charged Substrates Using Numerical Simulations on the Basis of the Poisson–Boltzmann Equation
    Yu Sugimoto, Yuki Kitazumi, Osamu Shirai, Masahiro Yamamoto, Kenji Kano · 2016 · The Journal of Physical Chemistry B
83. A ‘catch-and-release’ receptor for the cholera toxin
    Clare S. Mahon, Gemma C. Wildsmith, Diksha Haksar, Eyleen de Poel, Jeffrey Matthijn Beekman, Roland J. Pieters, Michael E. Webb, W. Bruce Turnbull · 2019 · Faraday Discussions
84. Radiolabelled Peptides: Optimal Candidates for Theranostic Application in Oncology
    Andrew J. Hall, Mohammad B. Haskali · 2021 · Australian Journal of Chemistry
85. Covalent 14-3-3 Molecular Glues and Heterobifunctional Molecules Against Nuclear Transcription Factors and Regulators
    Qian Shao, Tuong Nghi Duong, Inji Park, Daniel K. Nomura · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
86. Stabilizer‐Guided Inhibition of Protein–Protein Interactions
    L.‐G. Milroy, Maria Bartel, Morkos A. Henen, S. Leysen, Joris M. C. Adriaans, Luc Brunsveld, Isabelle Landrieu, Christian Ottmann · 2015 · Angewandte Chemie
87. Enhanced motivated behavior mediated by pharmacological targeting of the FGF14/Nav1.6 complex in nucleus accumbens neurons
    Nolan Michael Dvorak, Paul A. Wadsworth, Guillermo Aquino-Miranda, Pingyuan Wang, Douglas Senna Engelke, Jingheng Zhou, Nghi H. Nguyen, Aditya Kumar Singh, Giuseppe Aceto, Zahra Haghighijoo et al. · 2025 · Nature Communications
88. The Evolving Landscape of Protein Allostery: From Computational and Experimental Perspectives
    Srinivasan Ekambaram, Grigor Arakelov, Nikolay V. Dokholyan · 2025 · Journal of Molecular Biology
89. Visualization and quantification of dynamic STAT3 homodimerization in living cells using homoFluoppi
    Yusuke Okada, Taku Watanabe, Toru Shoji, Kyoko Taguchi, Naohisa Ogo, Akira Asai · 2018 · Scientific Reports
90. Covalent and noncovalent constraints yield a figure eight-like conformation of a peptide inhibiting the menin-MLL interaction
    Paulina Fortuna, Brian M. Linhares, Trupta Purohit, Jonathan Pollock, Tomasz Cierpicki, Jolanta E. Grembecka, Łukasz Berlicki · 2020 · European Journal of Medicinal Chemistry
91. Hydrogen bond surrogate helices as minimal mimics of protein α-helices
    Ganesh S. Jedhe, Paramjit S. Arora · 2021 · Methods in enzymology on CD-ROM/Methods in enzymology
92. Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a peptide-binding domain
    Shuaiqi Guo, Hossein Zahiri, Corey Alfred Stevens, Daniel C. Spaanderman, L.‐G. Milroy, Christian Ottmann, Luc Brunsveld, Ilja Karina Voets, Peter L. Davies · 2021 · Cell Reports
93. Crosslinked Aspartic Acids as Helix‐Nucleating Templates
    Hui Zhao, Qisong Liu, Hao Ran Geng, Yuan Tian, Min Cheng, Yan‐Hong Jiang, Ming‐Sheng Xie, Xiaogang Niu, Fan Jiang, Yaou Zhang et al. · 2016 · Angewandte Chemie
94. Des3PI: a fragment-based approach to design cyclic peptides targeting protein–protein interactions
    Maxence Delaunay, Tâp Ha‐Duong · 2022 · Journal of Computer-Aided Molecular Design
95. Self- and cross-attention accurately predicts metabolite–protein interactions
    Pedro Alonso Campana, Zoran Nikoloski · 2023 · NAR Genomics and Bioinformatics
96. Diffusion of Information throughout the Host Interactome Reveals Gene Expression Variations in Network Proximity to Target Proteins of Hepatitis C Virus
    Ettore Mosca, Roberta R. Alfieri, Luciano Milanesi · 2014 · PLoS ONE
97. HIF-1 promotes the expression of its α-subunit via an epigenetically regulated transactivation loop
    Daniel J. Asby, Francesco Cuda, Franciane Hoakwie, E Miranda, Ali Tavassoli · 2014 · Molecular BioSystems
98. DNA-modulated dimerization and oligomerization of cell membrane receptors
    Ahsan Ausaf Ali, Mingxu You · 2024 · Chemical Communications
99. AlphaFold Ensemble Competition Screens Enable Peptide Binder Design with Single-Residue Sensitivity
    Pernille Vosbein, Paula Paredes Vergara, Danny T. C. Huang, Andrew R. Thomson · 2024 · ACS Chemical Biology
100. Modulation of Protein–Protein Interactions with Molecular Glues in a Synthetic Condensate Platform
     Thijs W. van Veldhuisen, Renske M. J. Dijkstra, Auke A. Koops, Peter J. Cossar, Jan C. M. van Hest, Luc Brunsveld · 2025 · Journal of the American Chemical Society