Modulators of Protein–Protein Interactions

Milroy, Lech-Gustav, Grossmann, Tom N., Hennig, Sven, Brunsveld, Luc, Ottmann, Christian·2014·Chemical Reviews

Cited by (523)

Items 301–400 of 523

  1. Recognition of ASF1 by Using Hydrocarbon‐Constrained Peptides
    May Bakail, Silvia Rodriguez‐Marin, Zsófia Hegedüs, Marie E. Perrin, Françoise Ochsenbein, Andrew John Wilson · 2018 · ChemBioChem
  2. A systematic approach to identify host targets and rapidly deliver broad-spectrum antivirals
    Julien Olivet, Sibusiso B. Maseko, Alexander N. Volkov, Kourosh Salehi‐Ashtiani, Kalyan Das, Michael A. Calderwood, Jean‐Claude Twizere, Christoph Gorgulla · 2022 · Molecular Therapy
  3. New Compound Classes: Protein–Protein Interactions
    Christian Ottmann · 2015 · Handbook of experimental pharmacology
  4. Electrostatic roles in electron transfer from [NiFe] hydrogenase to cytochrome c 3 from Desulfovibrio vulgaris Miyazaki F
    Yu Sugimoto, Yuki Kitazumi, Osamu Shirai, Koji Nishikawa, Yoshiki Higuchi, Masahiro Yamamoto, Kenji Kano · 2017 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  5. HBx-Derived Constrained Peptides Inhibit the Secretion of Hepatitis B Virus Antigens
    Xiaodan Cai, Weihao Zheng, Xiaodong Shi, Longjian Chen, Zhihong Liu, Zigang Li · 2018 · Molecular Pharmaceutics
  6. Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119
    Philipp M. Cromm, Hélène Adihou, Shobhna Kapoor, Mercedes Vázquez–Chantada, Paul R. J. Davey, David Longmire, Elisabeth Hennes, Walter Hofer, Philipp Küchler, Elisabetta Chiarparin et al. · 2019 · ChemBioChem
  7. A new insight into subinteractomes of functional antagonists: Thromboxane (CYP5A1) and prostacyclin (CYP8A1) synthases
    Pavel V. Ershov, Evgeniy O. Yablokov, Victor Gavrilovich Zgoda, Yuri V. Mezentsev, Oksana V. Gnedenko, Leonid A. Kaluzhskiy, Andrey V. Svirid, Andrei A. Gilep, Sergey A. Usanov, Alexis S. Ivanov · 2021 · Cell Biology International
  8. Recent developments in the utility of saturated azaheterocycles in peptidomimetics
    Manish K. Singh, Mahesh K. Lakshman · 2021 · Organic & Biomolecular Chemistry
  9. Fragment‐Based Stabilizers of Protein–Protein Interactions through Imine‐Based Tethering
    M. Wolter, Dario Valenti, Peter J. Cossar, Laura M. Levy, Stanimira Hristeva, Thorsten Genski, Torsten Hoffmann, Luc Brunsveld, Dimitrios Tzalis, Christian Ottmann · 2020 · Angewandte Chemie
  10. A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53‐Mediated Apoptosis
    Misook Oh, Ji Hoon Lee, Heejo Moon, Yu-Jung Hyun, Hyun‐Suk Lim · 2015 · Angewandte Chemie
  11. Dual Functional Modification of Alkaline Amino Acids Induces the Self‐Assembly of Cylinder‐Like Tobacco Mosaic Virus Coat Proteins into Gear‐Like Architectures
    Jian‐Ting Zhang, Ranjith Kumar Kankala, Yihao Zhou, Jinchen Dong, Ai‐Zheng Chen, Qiangbin Wang · 2019 · Small
  12. Exploring Framework Nucleic Acids: A Perspective on Their Cellular Applications
    Zhaoyang Wang, Xin Wang, Yao He, Hui Chen Wu, Rui Mao, Haiyuan Wang, Liping Qiu · 2024 · JACS Au
  13. Harnessing Allostery to Modulate Protein–Protein Interactions: From Function to Therapeutic Innovations
    Sutanu Mukhopadhyay, Krishnendu Sinha, Suman Chakrabarty · 2025 · Journal of Molecular Biology
  14. Direkte Modulation von Aktivität und Funktion kleiner GTPasen
    Philipp M. Cromm, Jochen Spiegel, Tom N. Grossmann, Herbert Waldmann · 2015 · Angewandte Chemie
  15. Design criteria for minimalist mimics of protein–protein interface segments
    Jaru Taechalertpaisarn, Rui-Liang Lyu, Maritess Arancillo, Chen‐Ming Lin, Zhengyang Jiang, Lisa M. Pérez, Thomas R. Ioerger, Kevin Burgess · 2018 · Organic & Biomolecular Chemistry
  16. Different phosphorylation and farnesylation patterns tune Rnd3–14-3-3 interaction in distinct mechanisms
    Jun Hu, Xue-Meng Sun, Jingyun Su, Yufen Zhao, Yong‐Xiang Chen · 2021 · Chemical Science
  17. When Supramolecular Chemistry Meets Chemical Biology: New Strategies to Target Proteins through Host‐Guest Interactions
    Wenbing Cao, Xuewen Qin, Tao Liu · 2021 · ChemBioChem
  18. Coacervate Formed by an ATP-Binding Aptamer and Its Dynamic Behavior under Nonequilibrium Conditions
    Zhijun Liu, Jiaxin Chen, Qingwen Bai, Ya-nan Lin, Dehai Liang · 2022 · Langmuir
  19. Discovery of 14‐3‐3 PPI Stabilizers by Extension of an Amidine‐Substituted Thiophene Fragment
    Qi Wu, Federica Centorrino, X. Guillory, M. Wolter, Christian Ottmann, Peter J. Cossar, Luc Brunsveld · 2023 · ChemBioChem
  20. Synthesis of a Bcl9 Alpha-Helix Mimetic for Inhibition of PPIs by a Combination of Electrooxidative Phenol Coupling and Pd-Catalyzed Cross Coupling
    Martin Vareka, Benedikt Dahms, Mario Lang, Minh Hao Hoang, Melanie Trobe, Hansjörg Weber, Maximilian M. Hielscher, Siegfried R. Waldvogel, Rolf Breinbauer · 2020 · Catalysts
  21. Allosteric Modulators
    Shaoyong Lu, Jinyan Zhang · 2016 · Elsevier eBooks
  22. Terminal protection of peptides by interactions with proteins: A “signal-on” peptide-templated gold nanocluster beacon for label-free protein detection
    Qian Wen, Sili Yi, Qinlu Lin, Li‐Juan Tang, Jian‐Hui Jiang · 2021 · Talanta
  23. Bispidine as a β-strand nucleator: from a β-arch to self-assembled cages and vesicles
    Hanuman Singh, Akshay Chenna, Upanshu Gangwar, Julie Borah, Gaurav Goel, V. Haridas · 2021 · Chemical Science
  24. A Modular Synthesis of Teraryl‐Based α‐Helix Mimetics, Part 5: A Complete Set of Pyridine Boronic Acid Pinacol Esters Featuring Side Chains of Proteinogenic Amino Acids
    Melanie Trobe, Till Schreiner, Martin Vareka, Sebastian Grimm, Bernhard Wölfl, Rolf Breinbauer · 2022 · European Journal of Organic Chemistry
  25. Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity
    Jie Zang, Yves Cambet, Vincent Jaquet, Anders Bach · 2023 · Frontiers in Pharmacology
  26. Straightforward model construction and analysis of multicomponent biomolecular systems in equilibrium
    Nick H. J. Geertjens, Pim J. de Vink, Tim Wezeman, Albert Jan Markvoort, Luc Brunsveld · 2023 · RSC Chemical Biology
  27. Recent advances in the modulation of amyloid protein aggregation using the supramolecular host-guest approaches
    Debabrata Maity · 2023 · Biophysical Chemistry
  28. Disulfide Click Reaction for Stapling of S‐terminal Peptides
    Qing Yu, Leiyang Bai, Xuefeng Jiang · 2023 · Angewandte Chemie
  29. Assembly and Functionality of 2D Protein Arrays
    Mingming Du, Fanmeng Zeng, YueFei Wang, Yongjun Li, Guangcun Chen, Jiang Jiang, Qiangbin Wang · 2025 · Advanced Science
  30. Site-selective modification of native proteins
    Yujun Kim, Han Yi, Kyungdeok Seo, Hyun Soo Lee, Injae Shin · 2025 · Trends in Chemistry
  31. TAX1BP3 Is a SUMOylated Nucleocytoplasmic Shuttling Protein and Protects Against Vascular Neointimal Hyperplasia
    Hanyan Yang, Yulong Zhong, Wenjie Guo, Wenjing Guo, Boliang Chen, Zexuan Lin, Qin Zhang, Rongjun Zou, Xiaolong Cao, Fengxian Li et al. · 2025 · Circulation
  32. Stalis: A Computational Method for Template‐Based Ab Initio Ligand Design
    Hui Sun Lee, Wonpil Im · 2019 · Journal of Computational Chemistry
  33. Bicyclic Schellman Loop Mimics (BSMs): Rigid Synthetic C-Caps for Enforcing Peptide Helicity
    Tianxiong Mi, Duyen Nguyen, Kevin Burgess · 2023 · ACS Central Science
  34. Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair
    Harsha Gouda, Romila Mascarenhas, Markus Ruetz, Madeline Yaw, Ruma V. Banerjee · 2023 · Proceedings of the National Academy of Sciences
  35. Molecular electrostatic potential and volume-aided drug design based on the isoindolinone-containing cyclopeptide S-PK6
    Lei Zhao, Tingting Li, Hongyu Xu, Xiong Zhang, Huiming Lin, Na Liu, Yingxue Jin, Zhiqiang Wang · 2023 · New Journal of Chemistry
  36. Facile Peptide Macrocyclization and Multifunctionalization via Cyclen Installation
    Tsz‐Lam Cheung, Leo K. B. Tam, Wing‐Sze Tam, Leilei Zhang, Hei‐Yui Kai, Waygen Thor, Yue Wu, Pak‐Lun Lam, Yik‐Hoi Yeung, Chen Xie et al. · 2024 · Small Methods
  37. Novel peptide—based inhibitor for targeted inhibition of T cell function
    Ashna Gauthaman, Rini Jacob, Sneha Pasupati, Rajadurai Abarna, C. George Priya Doss, Anbalagan Moorthy · 2021 · Journal of Cell Communication and Signaling
  38. A Non‐coded β2,2‐Amino Acid with Isoxazoline Core Able to Stabilize Peptides Folding through an Unprecedented Hydrogen Bond
    Raffaella Bucci, Francesco Vaghi, Davide Di Lorenzo, Francesco Anastasi, Gianluigi Broggini, Leonardo Lo Presti, Alessandro Contini, Maria Luisa Gelmi · 2022 · European Journal of Organic Chemistry
  39. Explaining RANKL inhibition by OPG through quantum biochemistry computations and insights into peptide-design for the treatment of osteoporosis
    Bruno Lopes de Sousa, Ito L. Barroso-Neto, Evanildo F. Oliveira, Emerson Alberto Fonseca, Pedro de Lima‐Neto, Luiz O. Ladeira, V. N. Freire · 2016 · RSC Advances
  40. A Novel Long‐Range n to π* Interaction Secures the Smallest known α‐Helix in Water
    Huy N. Hoang, Chongyang Wu, Timothy A. Hill, Aline D. de Araujo, Paul V. Bernhardt, Ligong Liu, David P. Fairlie · 2019 · Angewandte Chemie
  41. Small-molecule inhibitors of the CD40–CD40L costimulatory interaction are effective in pancreatic islet transplantation and prevention of type 1 diabetes models
    Sung-Ting Chuang, Oscar Alcazar, B.M. Watts, Midhat H. Abdulreda, Péter Buchwald · 2024 · Frontiers in Immunology
  42. Integrating Protein Interaction Surface Prediction with a Fragment-Based Drug Design: Automatic Design of New Leads with Fragments on Energy Surfaces
    Luca Torielli, Stefano Artin Serapian, Lara Mussolin, Elisabetta Moroni, Giorgio Colombo · 2022 · Journal of Chemical Information and Modeling
  43. The role of N-terminal proline in stabilizing the Ant–Pro zipper motif
    Sanjeev Kheria, Roshna V. Nair, Amol S. Kotmale, Pattuparambil Ramanpillai Rajamohanan, Gangadhar J. Sanjayan · 2015 · New Journal of Chemistry
  44. Light-driven release of cucurbit[8]uril from a bivalent cage
    Pim J. de Vink, Tim van der Hek, Luc Brunsveld · 2021 · Chemical Science
  45. Recent Advances in β-catenin/BCL9 protein–protein Interaction Inhibitors
    Hao Zhang, Ya Bao, Chenglong Liu, Jianqi Li, Di Zhu, Qingwei Zhang · 2021 · Future Medicinal Chemistry
  46. Head-to-Tail Cross-Linking to Generate Bicyclic Helical Peptides with Enhanced Helicity and Proteolytic Stability
    Kai Chen, Yang Tang, Meng Yao Wu, Xiao-Cui Wan, Yanni Zhang, Xiaoxu Chen, Fei-Qiang Yu, Zhihui Cui, Jinming Ma, Zhaocai Zhou et al. · 2021 · Organic Letters
  47. On-Resin Synthesis of Linear Aryl Thioether Containing Peptides and in-Solution Cyclization via Cysteine SNAr Reaction
    Jian Li, Weihong Lai, Ao Pang, Lu Liu, Lianbao Ye, Xiao‐Feng Xiong · 2022 · Organic Letters
  48. Binding Dynamics of a Stapled Peptide Targeting the Transcription Factor NF−Y
    Canan Durukan, Federica Arbore, Rasmus Klintrot, Carlo Bigiotti, Ioana Mariuca Ilie, Jocelyne Vreede, Tom N. Grossmann, Sven Hennig · 2024 · ChemBioChem
  49. Probing Protein Surfaces: QSAR Analysis with Helix Mimetics
    Valeria Azzarito, Philip R. Rowell, Anna Barnard, Thomas A. Edwards, Andrew Macdonald, Stuart L. Warriner, Andrew John Wilson · 2015 · ChemBioChem
  50. Cucurbit[8]uril Reactivation of an Inactivated Caspase‐8 Mutant Reveals Differentiated Enzymatic Substrate Processing
    Dung T. Dang, Arthur H. A. M. van Onzen, Yvonne L. Dorland, Luc Brunsveld · 2018 · ChemBioChem
  51. Peptidomimetics II
    William D. Lubell · 2016 · Topics in heterocyclic chemistry
  52. From Degraders to Molecular Glues: New Ways of Breaking Down Disease‐Associated Proteins
    Yvonne A. Nagel, Adrian Britschgi, Antonio Ricci · 2021 · Wiley eBooks
  53. Molecular Glue Degraders: From Serendipity to Hunting and Design
    Luis Nieto‐Barrado, Ana Domostegui, Cristina Mayor‐Ruiz · 2022 · Wiley eBooks
  54. Patenting perspective on Keap1 inhibitors (2019–2024)
    Yongfu Luo, Wenlong Yang, Yuan Zhang, Shutong Jiang, Jingyu Zhu, Xiangyang Li, Qidong You, Mengchen Lu · 2025 · Expert Opinion on Therapeutic Patents
  55. Interrogating the potential of helical aromatic foldamers for protein recognition
    Sunbum Kwon, Vasily Morozov, Lingfei Wang, Pradeep K. Mandal, Stéphane Chaignepain, Céline Douat, Ivan Huc · 2024 · Organic & Biomolecular Chemistry
  56. ATP Inhibits the Transcription Factor STAT5b
    Angela Berg, Bianca Sperl, Thorsten Berg · 2019 · ChemBioChem
  57. Solid-phase parallel synthesis of 1,3-thiazole library adorned with dipeptidyl chains
    Min-Jeong Cha, Aizhan Abdildinova, Young‐Dae Gong · 2020 · Tetrahedron
  58. Protein-protein interaction and interference of carcinogenesis by supramolecular modifications
    Oluwatosin A. Saibu, Opeyemi Sodiq Hammed, Oladapo O. Oladipo, Tope Tunji Odunitan, Temitope M. Ajayi, Aderonke J. Adejuyigbe, Boluwatife T. Apanisile, Oluwatoba Emmanuel Oyeneyin, Adenrele T. Oluwafemi, Tolulope Ayoola et al. · 2023 · Bioorganic & Medicinal Chemistry
  59. Deciphering key genes involved in cisplatin resistance in kidney renal clear cell carcinoma through a combined in silico and in vitro approach
    Muneeba Malik, MAMOONA MAQBOOL, TOOBA NISAR, TAZEEM AKHTER, Javed Ahmed Ujan, Alanood Saeed Algarni, Fakhria A. Al‐Joufi, SULTAN SHAFI K. ALANAZI, MOHAMMAD HADI ALMOTARED, Mounir Mohamed Salem-Bekhit et al. · 2023 · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
  60. Bisphosphonate ligand mediated ultrasensitive capacitive protein sensor: complementary match of supramolecular and dynamic chemistry
    Gizem Ertürk, Maedeh Akhoundian, Kyra Lueg-Althoff, Sudhirkumar Shinde, Sing Yee Yeung, Martin Hedström, Thomas H. Schrader, Bo Mattìasson, Börje Sellergren · 2018 · New Journal of Chemistry
  61. Helix-Constrained Peptides Constructed by Head-to-Side Chain Cross-Linking Strategies
    Xiaoxu Chen, Yang Tang, Meng Yao Wu, Yanni Zhang, Kai Chen, Zhaocai Zhou, Ge‐Min Fang · 2021 · Organic Letters
  62. HOPPI-NMR: Hot-Peptide-Based Screening Assay for Inhibitors of Protein–Protein Interactions by NMR
    Diego Brancaccio, Salvatore Di Maro, Linda Cerofolini, Stefano Giuntini, Marco Fragai, Claudio Luchinat, Stefano Tomassi, Antonio Limatola, Pasquale Russomanno, Francesco Merlino et al. · 2020 · ACS Medicinal Chemistry Letters
  63. A NanoBRET-based assay monitoring interactions in the USP18 signaling hub identifies the first cell-penetrant small molecule compromising USP18/ISG15 binding
    Sandra Hess, Marta Campos Alonso, Michael J. D. Brand, Susan Lauw, Urs Lindenmann, Katharina Göbel, Paul P. Geurink, Günter Fritz, Rainer Riedl, Klaus‐Peter Knobeloch · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  64. De Novo Discovery of α,α-Disubstituted α-amino Acid-Containing α-helical Peptides as Competitive PPARγ PPI Inhibitors
    Maxwell Sigal, Markus Egner, Chikako Okada, Daniel Merk, Toru Sengoku, Takayuki Katoh, Hiroaki Suga · 2025 · Journal of the American Chemical Society
  65. Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groups
    Neda Rafieiolhosseini, Matthias Killa, Thorben Neumann, Niklas Tötsch, Jean‐Noël Grad, Alexander Höing, Thies Dirksmeyer, Jochen Niemeyer, Christian Ottmann, Shirley K. Knauer et al. · 2022 · Beilstein Journal of Organic Chemistry
  66. Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with Microtubules
    Jonas Neblik, Abbna Kirupakaran, Christine Beuck, Joel Mieres‐Pérez, Felix C. Niemeyer, My‐Hue Le, Ursula Telgheder, Jessica Felice Schmuck, Alexander Dudziak, Peter Bayer et al. · 2023 · Journal of the American Chemical Society
  67. Machine learning of metabolite–protein interactions from model-derived metabolic phenotypes
    Mahdis Habibpour, Zahra Razaghi‐Moghadam, Zoran Nikoloski · 2024 · NAR Genomics and Bioinformatics
  68. Single-Molecule Multivalent Interactions Revealed by Plasmon-Enhanced Fluorescence
    Kasper R. Okholm, Sjoerd W. Nooteboom, Johan Nygaard Vinther, Vincenzo Lamberti, Swayandipta Dey, Ebbe Sloth Andersen, Peter Zijlstra, Duncan S. Sutherland · 2024 · ACS Nano
  69. Towards optimizing peptide-based inhibitors of protein–protein interactions: predictive saturation variation scanning (PreSaVS)
    Kristina Hetherington, Som Dutt, Amaurys Ávila Ibarra, Emma E. Cawood, Fruzsina Hóbor, Derek N. Woolfson, Thomas A. Edwards, Adam S. Nelson, Richard Barry Sessions, Andrew John Wilson · 2021 · RSC Chemical Biology
  70. Inhibition of Protein–Protein Interactions: New Options for Developing Drugs against Neglected Tropical Diseases
    Thorsten Berg · 2017 · Angewandte Chemie International Edition
  71. Synthesis of Bis-Glyoxylamide Peptidomimetics Derived from Bis-N-acetylisatins Linked at C5 by a Methylene or Oxygen Bridge
    Venty Suryanti, Ruonan Zhang, Vina R. Aldilla, Mohan Madhav Bhadbhade, Naresh Kumar, David StC. Black · 2019 · Molecules
  72. Fusicoccin Keeps Getting Stickier: Modulation of an Adaptor Protein Interactome with a Molecular Glue Leads to Neurite Outgrowth
    Claire S. Harmange Magnani, Thomas J. Maimone · 2020 · Cell chemical biology
  73. Supramolecular self-assembly: A facile way to fabricate protein and peptide nanomaterials
    Luyang Zhao, Xuehai Yan · 2020 · Elsevier eBooks
  74. A Modular Synthesis of Teraryl‐Based α‐Helix Mimetics, Part 3: Iodophenyltriflate Core Fragments Featuring Side Chains of Proteinogenic Amino Acids
    Melanie Trobe, Martin Vareka, Till Schreiner, Patrick Simon Dobrounig, Carina Doler, Ella B. Holzinger, Andreas Steinegger, Rolf Breinbauer · 2022 · European Journal of Organic Chemistry
  75. Rationally Designed Semisynthetic Natural Product Analogues for Stabilization of 14‐3‐3 Protein–Protein Interactions
    Sebastian A. Andrei, Pim J. de Vink, Eline Sijbesma, Ling Han, Luc Brunsveld, Nobuo Kato, Christian Ottmann, Yusuke Higuchi · 2018 · Angewandte Chemie
  76. Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling
    Mathias Wendt, Rosa Bellavita, Alan Gerber, Nina‐Louisa Efrém, Thirza van Ramshorst, Nicholas M. Pearce, Paul R. J. Davey, Isabel Everard, Mercedes Vázquez–Chantada, Elisabetta Chiarparin et al. · 2021 · Angewandte Chemie
  77. Analysis of the interaction of cyclosporine congeners with cell membrane models
    Mizuka Nakao, Yuki Takechi‐Haraya, Takashi Ohgita, Hiroyuki Saito, Yosuke Demizu, Ken‐ichi Izutsu, Kumiko Sakai‐Kato · 2022 · Journal of Pharmaceutical and Biomedical Analysis
  78. How Do Molecular Tweezers Bind to Proteins? Lessons from X-ray Crystallography
    Arthur T. Porfetye, Patricia Stege, Rocio Rebollido-Rios, Daniel E. Hoffmann, Thomas H. Schrader, Ingrid R. Vetter · 2024 · Molecules
  79. Protein–Protein Interface Topology as a Predictor of Secondary Structure and Molecular Function Using Convolutional Deep Learning
    Benjamin Bouvier · 2021 · Journal of Chemical Information and Modeling
  80. Protein-Protein Interactions: An Overview
    Edson Luiz Folador, Sandeep Tiwari, Camila E. Da Paz Barbosa, Syed Babar Jamal, Marco Da Costa Schulze, Debmalya Barh, Vasco Azevedo · 2018 · Elsevier eBooks
  81. SAR by 1D NMR
    Neal Joseph Zondlo · 2019 · Journal of Medicinal Chemistry
  82. Structure-based design of an aromatic helical foldamer–protein interface
    Lingfei Wang, Céline Douat, Johannes Sigl, Post Sai Reddy, Lucile Fischer, Béatrice Langlois d’Estaintot, Zhiwei Liu, Vojislava Pophristic, Yuwei Yang, Yingkai Zhang et al. · 2025 · Chemical Science
  83. Multimodal Contrastive Learning for Protein–Protein Interaction Inhibitor Prediction
    Zitong Zhang, Zhixian Wang, Lingling Zhao, Junjie Wang, Chunyu Wang · 2024 · IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
  84. A pharmacological modality to sequester homomeric proteins
    Ella Livnah, Ohad Suss, Adi Rogel, Atar Gilat, Yuval Abdan, José A. Villegas, Ronen Gabizon, Almog Nadir, Yoav Shamir, Noam Y. Steinman et al. · 2026 · Nature Chemical Biology
  85. Short Oligourea Foldamers as N‐ or C‐Caps for Promoting α‐Helix Formation in Water
    Laura Mauran, Coralie Assailly, Sébastien R. Goudreau, Benoı̂t Odaert, Gilles Guichard, Morgane Pasco · 2024 · ChemBioChem
  86. Tyrosinase‐Catalyzed Peptide Stapling Using Para‐Amino Phenylalanine and Tyrosine Anchoring Residues
    Nan Wang, Zhengyang Xu, Huaxing Shen, Wei Cong, Shuai Zhang, Honggang Hu, Xiang Li · 2025 · Angewandte Chemie
  87. Funktionelle Inhibition der krebsrelevanten Interaktion von Survivin und Histon H3 mit einem Guanidiniumcarbonylpyrrol‐Liganden
    Cecilia Vallet, Dennis Aschmann, Christine Beuck, Matthias Killa, Annika Meiners, Marcel Mertel, Martin Ehlers, Peter Bayer, Carsten Schmuck, Michael Giese et al. · 2020 · Angewandte Chemie
  88. Traceless solid-phase synthesis and β-turn propensity of 1,3-thiazole-based peptidomimetics
    Aizhan Abdildinova, Young‐Dae Gong · 2021 · RSC Advances
  89. Diazaborine-Mediated Bicyclization of Native Peptides with Inducible Reversibility
    Rahi M. Reja, Brittney Chau, Jianmin Gao · 2023 · Organic Letters
  90. Visualized and Quantitative Conformational Analysis of Peptidomimetics
    Hajime Takashima, Atsushi Yoshimori, Eiji Honda, Tomonori Taguri, Jun Ozawa, Masaji Kasai, Satoshi Shuto, Dai Takehara · 2021 · ACS Omega
  91. A Modular Synthesis of Teraryl‐Based α‐Helix Mimetics, Part 4: Core Fragments with Two Halide Leaving Groups Featuring Side Chains of Proteinogenic Amino Acids
    Melanie Trobe, Julia Blesl, Martin Vareka, Till Schreiner, Rolf Breinbauer · 2022 · European Journal of Organic Chemistry
  92. Stackabilization: self-assembling bispidinophanes
    Sakshi Sharma, M. V. S. Gopalakrishna, Paloth Venugopalan, Cherumuttathu Hariharan Suresh, V. Haridas · 2015 · Tetrahedron
  93. Modeling and Design of Peptidomimetics to Modulate Protein–Protein Interactions
    Andrew M. Watkins, Richard Bonneau, Paramjit S. Arora · 2017 · Methods in molecular biology
  94. Mapping molecular binding by means of conformational dynamics measurements
    Noelle M. do Nascimento, Augusto Juste-Dolz, Paulo R. Bueno, Isidro S. Monzó, Roberto Tejero, José Luis López-Paz, Ángel Maquieira, Sergi Morais, David Giménez-Romero · 2018 · RSC Advances
  95. Manumycin Polyketides Act as Molecular Glues Between UBR7 and P53 to Impair Breast Cancer Pathogenicity
    Yosuke Isobe, Mikiko Okumura, Ross White, Lynn M. McGregor, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Thomas J. Maimone, Daniel K. Nomura · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  96. PPIscout: Protein–protein interaction site hotspot mapping using mixed amino acid–water molecular dynamics simulation
    Sutanu Mukhopadhyay, Suman Chakrabarty · 2025 · Journal of Chemical Sciences
  97. Targeting protein protein interactions and their modulators to enable new therapeutic strategies for human diseases
    Aftab Alam, Maria J. Fernández-Cabezudo, Rifat Hamoudi, Basel K. al-Ramadi · 2026 · npj Systems Biology and Applications
  98. Advancing protein engineering via organic chemistry
    Raj V. Nithun, Manjeet Singh, Adam Baransi, Muhammad Jbara · 2026 · Communications Chemistry
  99. Examination of the Effect of N‐terminal Diproline and Charged Side Chains on the Stabilization of Helical Conformation in Alanine–based Short Peptides: A Molecular Dynamics Study
    Bhupesh Goyal, Kinshuk Raj Srivastava, Susheel Durani · 2016 · ChemistrySelect
  100. A Ligase‐Based Two‐Step Approach for the Generation of Bicyclic Peptides Containing a Benzylphenyl Thioether Framework
    Hua Zhang, Hui‐Min Wei, Jun‐Hao Xue, Zhe‐Min Xia, Feng‐Hao Zheng, Xiao‐Cui Wan, Zhou Li, Ge‐Min Fang · 2025 · ChemBioChem