Modulators of Protein–Protein Interactions

Cited by (523)

Items 101–200 of 523

1. Exploring and Controlling the Polymorphism in Supramolecular Assemblies of Carbohydrates and Proteins
   Chendi Gao, Guosong Chen · 2020 · Accounts of Chemical Research
2. Biospecific Chemistry for Covalent Linking of Biomacromolecules
   Li Cao, Lei Wang · 2024 · Chemical Reviews
3. Structure-based inhibition of protein–protein interactions
   Andrew M. Watkins, Paramjit S. Arora · 2014 · European Journal of Medicinal Chemistry
4. Peptide Nanomaterials Designed from Natural Supramolecular Systems
   Hiroshi Inaba, Kazunori Matsuura · 2018 · The Chemical Record
5. Protein–Protein Interactions as Drug Targets
   Malgorzata Skwarczynska, Christian Ottmann · 2015 · Future Medicinal Chemistry
6. Peptide‐based covalent inhibitors of protein–protein interactions
   Felix M. Paulussen, Tom N. Grossmann · 2022 · Journal of Peptide Science
7. De novo coiled-coil peptides as scaffolds for disrupting protein–protein interactions
   Jordan M. Fletcher, Katherine A. Horner, Gail J. Bartlett, Guto G. Rhys, Andrew John Wilson, Derek N. Woolfson · 2018 · Chemical Science
8. DNA-Encoded Combinatorial Library of Macrocyclic Peptoids
   Min Hyeon Shin, KangJu Lee, Hyun‐Suk Lim · 2019 · Bioconjugate Chemistry
9. Development of Proteins for High‐Performance Energy Storage Devices: Opportunities, Challenges, and Strategies
   Tianyi Wang, Di He, Hang Yao, Xin Yu Guo, Bing Sun, Guoxiu Wang · 2022 · Advanced Energy Materials
10. Disulfide Click Reaction for Stapling of S‐terminal Peptides
    Qing Yu, Leiyang Bai, Xuefeng Jiang · 2023 · Angewandte Chemie International Edition
11. Modulating Protein–Protein Interactions with Visible‐Light‐Responsive Peptide Backbone Photoswitches
    Lea Albert, Alberto Peñalver, Nemanja Djoković, Laura Werel, Malte Hoffarth, Dušan Ružić, Jing Xu, Lars‐Oliver Essen, Katarina M. Nikolic, Yali Dou et al. · 2019 · ChemBioChem
12. A Comprehensive Overview of Small-Molecule Androgen Receptor Degraders: Recent Progress and Future Perspectives
    Si Ha, Guoshun Luo, Hua Xiang · 2022 · Journal of Medicinal Chemistry
13. Tackling Undruggable Targets with Designer Peptidomimetics and Synthetic Biologics
    Colin Swenson, Gunasheil Mandava, Deborah M. Thomas, Raymond E. Moellering · 2024 · Chemical Reviews
14. 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface
    T. Karlberg, Péter Hornyák, A.F. Pinto, Stefina Milanova, Mahsa Ebrahimi, Mikael J. Lindberg, Nikolai J. L. Püllen, Axel Nordström, Elinor Löverli, Rémi Caraballo et al. · 2018 · Nature Communications
15. Biomimetic Sensing System for Tracing Pb2+ Distribution in Living Cells Based on the Metal–Peptide Supramolecular Assembly
    Shilang Gui, Yanyan Huang, Yuan‐Yuan Zhu, Yulong Jin, Rui Zhao · 2019 · ACS Applied Materials & Interfaces
16. Cucurbituril‐Based Biomacromolecular Assemblies
    Yaohua Liu, Ying‐Ming Zhang, Hua‐Jiang Yu, Yu Liu · 2020 · Angewandte Chemie
17. Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2
    Sarath Ramachandran, Nikolai Makukhin, Kevin Haubrich, Manjula Nagala, Beth Forrester, Dylan M. Lynch, Ryan Casement, Andrea Testa, Elvira Bruno, Rosaria Gitto et al. · 2023 · Nature Communications
18. PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling
    Agata Nawrotek, Sarah Benabdi, Supaporn Niyomchon, Marie-Hélène Kryszke, Christophe Ginestier, Tatiana Cañeque, Livia Tepshi, Angelica Mariani, Robert P. St.Onge, Guri N. Giaever et al. · 2019 · Nature Chemical Biology
19. Targeting protein-protein interaction interfaces in COVID-19 drug discovery
    Chung‐ke Chang, Shanmeng Lin, Roshan Satange, Shih‐Chao Lin, Sin-Cih Sun, Hung‐Yi Wu, Kylene Kehn‐Hall, Ming‐Hon Hou · 2021 · Computational and Structural Biotechnology Journal
20. Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction
    Lei Wang, Li Li, Zihan Zhou, Zhengyu Jiang, Qidong You, Xiaoli Xu · 2017 · European Journal of Medicinal Chemistry
21. Scanning Protein Surfaces with DNA‐Encoded Libraries
    Verena B. K. Kunig, Marco Potowski, Mateja Klika Škopić, Andreas Brunschweiger · 2020 · ChemMedChem
22. Bioinspired recognition in metal-organic frameworks enabling precise sieving separation of fluorinated propylene and propane mixtures
    Wei Xia, Zhijie Zhou, Liangzheng Sheng, Lihang Chen, Fuxing Shen, Zheng Fang, Zhiguo Zhang, Qiwei Yang, Qilong Ren, Zongbi Bao · 2024 · Nature Communications
23. Stapled Voltage-Gated Calcium Channel (CaV) α-Interaction Domain (AID) Peptides Act As Selective Protein–Protein Interaction Inhibitors of CaV Function
    Felix Findeisen, Marta Campiglio, Hyunil Jo, Fayal Abderemane-Ali, Christine H. Rumpf, Lianne Pope, Nathan D. Rossen, Bernhard E. Flucher, William F. DeGrado, Daniel L. Minor · 2017 · ACS Chemical Neuroscience
24. Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action
    James I. Robinson, Euan W. Baxter, Robin Leslie Owen, Maren Thomsen, Darren Charles Tomlinson, Mark P. Waterhouse, Stephanie J. Win, Joanne E. Nettleship, Christian Tiede, Richard J. Foster et al. · 2017 · Proceedings of the National Academy of Sciences
25. Computational Modeling as a Tool to Investigate PPI: From Drug Design to Tissue Engineering
    Juan Jesús Pérez, Román A. Pérez, Alberto Pérez · 2021 · Frontiers in Molecular Biosciences
26. Structural Basis of Inhibition of ERα-Coactivator Interaction by High-Affinity N-Terminus Isoaspartic Acid Tethered Helical Peptides
    Mingsheng Xie, Hui Zhao, Qisong Liu, Yujia Zhu, Feng Yin, Yujie Liang, Yan‐Hong Jiang, Dongyuan Wang, Kuan Hu, Xuan Qin et al. · 2017 · Journal of Medicinal Chemistry
27. Towards rational computational peptide design
    Liwei Chang, Arup Mondal, Alberto Pérez · 2022 · Frontiers in Bioinformatics
28. Computational methods to design cyclic peptides
    Sean M. McHugh, Julia R. Rogers, Sarah A Solomon, Hongtao Yu, Yu‐Shan Lin · 2016 · Current Opinion in Chemical Biology
29. Computational methods-guided design of modulators targeting protein-protein interactions (PPIs)
    Yuran Qiu, Xinyi Li, Xinheng He, Jun Pu, Jian Zhang, Shaoyong Lu · 2020 · European Journal of Medicinal Chemistry
30. From Concepts to Inhibitors: A Blueprint for Targeting Protein–Protein Interactions
    Seong Ho Hong, Thu Trang Nguyễn, Joseph F. Ongkingco, Alex Nazzaro, Paramjit S. Arora · 2025 · Chemical Reviews
31. Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase
    Alejandro Revuelto, Marta Ruiz‐Santaquiteria, Héctor de Lucio, Ana M. Gamo, Alejandra Angela Carriles, Kilian Jesús Gutiérrez, Pedro A. Sánchez‐Murcia, J.A. Hermoso, Federico Gago, María‐José Camarasa et al. · 2019 · ACS Infectious Diseases
32. SPLINTS: small-molecule protein ligand interface stabilizers
    Eric S. Fischer, Eunyoung Park, Michael J. Eck, Nicolas H. Thomä · 2016 · Current Opinion in Structural Biology
33. Increased Conformational Flexibility of a Macrocycle–Receptor Complex Contributes to Reduced Dissociation Rates
    Adrian Glas, Eike‐Christian Wamhoff, Dennis M. Krüger, Christoph Rademacher, Tom N. Grossmann · 2017 · Chemistry - A European Journal
34. A tetrameric protein scaffold as a nano-carrier of antitumor peptides for cancer therapy
    Bohan Ma, F. Niu, Xiaoyan Qu, Wangxiao He, Chao Feng, Simeng Wang, Zhenlin Ouyang, Jin Yan, Yurong Wen, Dan Xu et al. · 2019 · Biomaterials
35. Synthetic Control of Tertiary Helical Structures in Short Peptides
    Michael G. Wuo, Seong Ho Hong, Arunima Singh, Paramjit S. Arora · 2018 · Journal of the American Chemical Society
36. Different stapling-based peptide drug design: Mimicking α-helix as inhibitors of protein–protein interaction
    Xiang Li, Yan Zou, Honggang Hu · 2018 · Chinese Chemical Letters
37. Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction
    Jessica Iegre, P. Brear, David J. Baker, Yaw Sing Tan, Eleanor L. Atkinson, Hannah F. Sore, Daniel H. O’Donovan, Chandra Shekhar Verma, Marko Hyvönen, David R. Spring · 2019 · Chemical Science
38. Engineering selective competitors for the discrimination of highly conserved protein-protein interaction modules
    Charlotte Rimbault, Kashyap Maruthi, Christelle Breillat, Camille Genuer, Sara Crespillo, Virginia Puente‐Muñoz, Ingrid Chamma, Isabel Gauthereau, Ségolène Antoine, Coraline Thibaut et al. · 2019 · Nature Communications
39. An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-κB—Utilizing a Reversible Covalent Tethering Approach
    M. Wolter, Dario Valenti, Peter J. Cossar, Stanimira Hristeva, Laura M. Levy, Thorsten Genski, Torsten Hoffmann, Luc Brunsveld, Dimitrios Tzalis, Christian Ottmann · 2021 · Journal of Medicinal Chemistry
40. Molecular Design for Dual Modulation Effect of Amyloid Protein Aggregation
    Lijuan Zhu, Yang Song, Pin-Nan Cheng, Jeffrey S. Moore · 2015 · Journal of the American Chemical Society
41. 14‐3‐3 Protein‐Protein Interactions: From Mechanistic Understanding to Their Small‐Molecule Stabilization
    Bente A. Somsen, Peter J. Cossar, Michelle R. Arkin, Luc Brunsveld, Christian Ottmann · 2024 · ChemBioChem
42. A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction
    Ewa Surmiak, Aleksandra Twarda‐Clapa, Krzysztof M. Żak, Bogdan Musielak, Marcin D. Tomala, Katarzyna Kubica, P. Grudnik, Mariusz Madej, Mateusz Jabłoński, Jan Potempa et al. · 2016 · ACS Chemical Biology
43. Molecular insight into specific 14-3-3 modulators: Inhibitors and stabilisers of protein–protein interactions of 14-3-3
    Alwin M. Hartman, Anna K. H. Hirsch · 2017 · European Journal of Medicinal Chemistry
44. Family-wide Analysis of the Inhibition of Arf Guanine Nucleotide Exchange Factors with Small Molecules: Evidence of Unique Inhibitory Profiles
    Sarah Benabdi, François Peurois, Agata Nawrotek, Jahnavi Chikireddy, Tatiana Cañeque, Takao Yamori, Isamu Shiina, Yoshimi Ohashi, Shingo Dan, Raphaël Rodriguez et al. · 2017 · Biochemistry
45. Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes
    Sebastian A. Andrei, Femke A. Meijer, João Filipe Neves, Luc Brunsveld, Isabelle Landrieu, Christian Ottmann, L.‐G. Milroy · 2018 · ACS Chemical Neuroscience
46. Covalent Targeting of Ras G12C by Rationally Designed Peptidomimetics
    Daniel Y. Yoo, Andrew D. Hauser, Stephen T. Joy, Dafna Bar‐Sagi, Paramjit S. Arora · 2020 · ACS Chemical Biology
47. Cleavable and tunable cysteine-specific arylation modification with aryl thioethers
    Jian Li, Junjie Deng, Zhibin Yin, Qi-Long Hu, Ge Yang, Zhendong Song, Ying Zhang, Albert S. C. Chan, Huilin Li, Xiao‐Feng Xiong · 2021 · Chemical Science
48. Perfluoro-tert-butyl Homoserine Is a Helix-Promoting, Highly Fluorinated, NMR-Sensitive Aliphatic Amino Acid: Detection of the Estrogen Receptor·Coactivator Protein–Protein Interaction by 19F NMR
    Caitlin M. Tressler, Neal Joseph Zondlo · 2017 · Biochemistry
49. Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction
    Ewa Surmiak, Constantinos G. Neochoritis, Bogdan Musielak, Aleksandra Twarda‐Clapa, Katarzyna Kurpiewska, Grzegorz Dubin, Carlos Jaime Camacho, Tad A. Holak, Alexander S. S. Dömling · 2016 · European Journal of Medicinal Chemistry
50. Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor
    Bruce J. MacLachlan, Georgina H. Mason, Alexander Greenshields‐Watson, Frédéric Triebel, Awen Gallimore, David K. Cole, Andrew J Godkin · 2020 · European Journal of Immunology
51. Targeting protein-protein interactions in drug discovery: Modulators approved or in clinical trials for cancer treatment
    Cristina Camps-Fajol, Debora Cavero, Jordi Minguillón, Jordi Surrallés · 2024 · Pharmacological Research
52. A systematic molecular dynamics approach to the study of peptide Keap1–Nrf2 protein–protein interaction inhibitors and its application to p62 peptides
    Mengchen Lu, Zhenwei Yuan, Yong-Lin Jiang, Zhiyun Chen, Qidong You, Zhengyu Jiang · 2016 · Molecular BioSystems
53. Targeted Inhibition of the NCOA1/STAT6 Protein–Protein Interaction
    Yeongju Lee, Heeseok Yoon, Sung‐Min Hwang, Min Kyung Shin, Ji Hoon Lee, Misook Oh, Sin‐Hyeog Im, Jaeyoung Song, Hyun‐Suk Lim · 2017 · Journal of the American Chemical Society
54. Biophysical and structural insight into the USP8/14‐3‐3 interaction
    Federica Centorrino, Alice Ballone, M. Wolter, Christian Ottmann · 2018 · FEBS Letters
55. From protein total synthesis to peptide transamidation and metathesis: playing with the reversibility of N,S-acyl or N,Se-acyl migration reactions
    Oleg Melnyk, Vangelis Agouridas · 2014 · Current Opinion in Chemical Biology
56. Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?
    Jessica Roos, Sabine Grösch, Oliver Werz, Peter Schröder, Slava Ziegler, Simone Fulda, Patrick Paulus, Anja Urbschat, Benjamin R. Kuhn, Isabelle V. Maucher et al. · 2015 · Pharmacology & Therapeutics
57. Designing Well-Structured Cyclic Pentapeptides Based on Sequence–Structure Relationships
    Diana P. Slough, Sean M. McHugh, Ashleigh E. Cummings, Peng Dai, Bradley L. Pentelute, Joshua A. Kritzer, Yu‐Shan Lin · 2018 · The Journal of Physical Chemistry B
58. Lenalidomide Stabilizes Protein–Protein Complexes by Turning Labile Intermolecular H-Bonds into Robust Interactions
    Marina Miñarro-Lleonar, Andrea Bertran‐Mostazo, Jorge Duro, Xavier Barril, Jordi Juárez‐Jiménez · 2023 · Journal of Medicinal Chemistry
59. The Development of a Versatile Trifunctional Scaffold for Biological Applications
    Václav Vaněk, Jan Pícha, Benjamin Fabre, Miloš Buděšı́nský, Martin Lepšı́k, Jiřı́ Jiráček · 2015 · European Journal of Organic Chemistry
60. Protein Camouflage: Supramolecular Anion Recognition by Ubiquitin
    Madeleine Mallon, Som Dutt, Thomas H. Schrader, Peter B. Crowley · 2016 · ChemBioChem
61. Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid
    Antonis D. Tsiailanis, Alexander Renziehausen, Sofia Kiriakidi, Eirinaios I. Vrettos, Georgios S. Markopoulos, Nisar Sayyad, Baydaa Hirmiz, Marie‐Isabel Aguilar, Mark P. Del Borgo, Evangelos Kolettas et al. · 2020 · Free Radical Biology and Medicine
62. Oligomeric Remodeling by Molecular Glues Revealed Using Native Mass Spectrometry and Mass Photometry
    Xiaojing Huang, Hari Kamadurai, Piro Siuti, Ezaz Ahmed, Jack L. Bennett, William A. Donald · 2023 · Journal of the American Chemical Society
63. Selective fluorescent labeling of cellular proteins and its biological applications
    Joo Hee Choi, Sooin Kim, On‐Yu Kang, Seong Yun Choi, Ji Young Hyun, Hyun Soo Lee, Injae Shin · 2024 · Chemical Society Reviews
64. Exploiting anthracene photodimerization within peptides: light induced sequence-selective DNA binding
    Gemma A. Bullen, James H. R. Tucker, Anna F. A. Peacock · 2015 · Chemical Communications
65. 1,4,5-Trisubstituted Imidazole-Based p53–MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers
    Aleksandra Twarda‐Clapa, Sylwia Krzanik, Katarzyna Kubica, Katarzyna Guzik, Beata Łabuzek, Constantinos G. Neochoritis, Kareem Khoury, Kaja Kowalska, Mirosława Czub, Grzegorz Dubin et al. · 2017 · Journal of Medicinal Chemistry
66. Current Trends in Macrocyclic Drug Discovery and beyond -Ro5
    Sulejman Alihodžić, Mirjana Bukvić, Ivaylo Elenkov, Antun Hutinec, Sanja Koštrun, Dijana Pešić, Gordon Saxty, Linda Tomašković, Dinko Žiher · 2018 · Progress in medicinal chemistry
67. Clinical candidates modulating protein-protein interactions: The fragment-based experience
    Dario Valenti, Stanimira Hristeva, Dimitrios Tzalis, Christian Ottmann · 2019 · European Journal of Medicinal Chemistry
68. Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction
    Hengzhi Sun, Jin‐Zheng Wang, Shengjie Liu, Xinyu Zhou, Liang Xiang Dai, Caiping Chen, Qing‐Long Xu, Xiaoan Wen, Keguang Cheng, Hongbin Sun et al. · 2021 · Journal of Chemical Information and Modeling
69. Small-Molecule Inhibitors of the CD40–CD40L Costimulatory Protein–Protein Interaction
    Jinshui Chen, Yun Gyu Song, Damir Bojadzic, Alejandro Tamayo, Ana Marie Landin, Bonnie B. Blomberg, Péter Buchwald · 2017 · Journal of Medicinal Chemistry
70. Orthogonal functionalisation of α-helix mimetics
    Anna Barnard, Kérya Long, David J. Yeo, Jennifer A. Miles, Valeria Azzarito, George M. Burslem, Panchami Prabhakaran, Thomas A. Edwards, Andrew John Wilson · 2014 · Organic & Biomolecular Chemistry
71. A Cyclic Peptide Mimic of the β-Amyloid Binding Domain on Transthyretin
    Patricia Y. Cho, Gururaj Joshi A, Melissa Boersma, Jeffrey Allan Johnson, Regina M. Murphy · 2015 · ACS Chemical Neuroscience
72. Screening-based approaches to identify small molecules that inhibit protein–protein interactions
    Choi, Sehee, Choi, Kang-Yell · 2017 · Expert Opinion on Drug Discovery
73. Metal complexes as “protein surface mimetics”
    Sarah H. Hewitt, Andrew John Wilson · 2016 · Chemical Communications
74. Self-Assembled Protein–Aromatic Foldamer Complexes with 2:3 and 2:2:1 Stoichiometries
    Michał Jewgiński, T. Granier, Béatrice Langlois d’Estaintot, Lucile Fischer, Cameron D. Mackereth, Ivan Huc · 2017 · Journal of the American Chemical Society
75. Proteomimetics of Natural Regulators of JAK–STAT Pathway: Novel Therapeutic Perspectives
    Sara La Manna, Ilaria De Benedictis, Daniela Marasco · 2022 · Frontiers in Molecular Biosciences
76. Combining Chemical Protein Synthesis and Random Nonstandard Peptides Integrated Discovery for Modulating Biological Processes
    Abhishek Saha, Hiroaki Suga, Ashraf Brik · 2023 · Accounts of Chemical Research
77. Small Molecules as Anti-TNF Drugs
    Victoria Richmond, Flavia Mariana Michelini, Carlos Alberto Bueno, Laura Edith Alché, Javier Alberto Ramirez · 2015 · Current Medicinal Chemistry
78. Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL
    Tahsin F. Kellici, Μaria V. Chatziathanasiadou, Min‐Sung Lee, Nisar Sayyad, Elena G. Geromichalou, Eirinaios I. Vrettos, Antonis D. Tsiailanis, Seung‐Wook Chi, George D. Geromichalos, Thomas Mavromoustakos et al. · 2017 · Organic & Biomolecular Chemistry
79. The role of protein–protein interactions in the intracellular traffic of the potassium channels TASK-1 and TASK-3
    Markus Kilisch, Olga Lytovchenko, Blanche Schwappach, Vijay Renigunta, Jürgen Daut · 2015 · Pflügers Archiv - European Journal of Physiology
80. A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14‐3‐3
    Pim J. de Vink, Jeroen M. Briels, Thomas H. Schrader, L.‐G. Milroy, Luc Brunsveld, Christian Ottmann · 2017 · Angewandte Chemie
81. Probing the 14-3-3 Isoform-Specificity Profile of Protein–Protein Interactions Stabilized by Fusicoccin A
    Ananya Sengupta, Josue Liriano, Ewa A. Bienkiewicz, Brian G. Miller, James H. Frederich · 2020 · ACS Omega
82. Photo‐Controlled Reversible Microtubule Assembly Mediated by Paclitaxel‐Modified Cyclodextrin
    Ying‐Ming Zhang, Ni‐Yuan Zhang, Kui Xiao, Qilin Yu, Yu Liu · 2018 · Angewandte Chemie
83. Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells
    Christian Lis, Stefan Rubner, Martin Roatsch, Angela Berg, Tyler Gilcrest, Darwin Fu, Elizabeth Dong Nguyen, Anne-Marie Schmidt, Harald Krautscheid, Jens Meiler et al. · 2017 · Scientific Reports
84. In-Tether Chiral Center Induced Helical Peptide Modulators Target p53-MDM2/MDMX and Inhibit Tumor Growth in Stem-Like Cancer Cell
    Kuan Hu, Feng Yin, Mengyin Yu, Chengjie Sun, Jingxu Li, Yujie Liang, Wenjun Li, Mingsheng Xie, Yuanzhi Lao, Wei Ping Liang et al. · 2017 · Theranostics
85. Discovering protein–protein interaction stabilisers by native mass spectrometry
    Jeddidiah Bellamy‐Carter, Manjari Mohata, Marta Falcicchio, Jaswir Basran, Yusuke Higuchi, Richard G. Doveston, Aneika C. Leney · 2021 · Chemical Science
86. Recent advances in automated protein design and its future challenges
    Setiawan, Dani, Brender, Jeffrey, Zhang, Yang · 2018 · Expert Opinion on Drug Discovery
87. Structural development of stapled short helical peptides as vitamin D receptor (VDR)–coactivator interaction inhibitors
    Takashi Misawa, Yosuke Demizu, Megumi Kawamura, Nanako Yamagata, Masaaki Kurihara · 2015 · Bioorganic & Medicinal Chemistry
88. Synthesis and Evaluation of a Library of Trifunctional Scaffold-Derived Compounds as Modulators of the Insulin Receptor
    Benjamin Fabre, Jan Pícha, Václav Vaněk, Irena Selicharová, Martina Chrudinová, Michaela Collinsová, Lenka Žáková, Miloš Buděšı́nský, Jiřı́ Jiráček · 2016 · ACS Combinatorial Science
89. Macrocyclic peptides as regulators of protein-protein interactions
    Yang Zi Jiang, Hongyi Long, Yu‐Jie Zhu, Yi Zeng · 2018 · Chinese Chemical Letters
90. Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase
    Leitch, Eilidh K., Elumalai, Nagarajan, Fridén-Saxin, Maria, Dahl, Göran, Wan, Paul, Clarkson, Paul, Valeur, Eric, Pairaudeau, Garry, Boyd, Helen, Tavassoli, Ali · 2018 · Chemical Science
91. Recent progress in the development of protein–protein interaction inhibitors targeting androgen receptor–coactivator binding in prostate cancer
    Éric Biron, François Bédard · 2015 · The Journal of Steroid Biochemistry and Molecular Biology
92. Selective and Potent Proteomimetic Inhibitors of Intracellular Protein–Protein Interactions
    Anna Barnard, Kérya Long, Heather L. Martin, Jennifer A. Miles, Thomas A. Edwards, Darren Charles Tomlinson, Andrew Macdonald, Andrew John Wilson · 2015 · Angewandte Chemie
93. Diaminodiacid-based solid-phase synthesis of all-hydrocarbon stapled α-helical peptides
    Fengliang Wang, Ye Guo, Si-Jian Li, Qingxiang Guo, Jing Min Shi, Yi‐Ming Li · 2015 · Organic & Biomolecular Chemistry
94. Screening of Small-Molecule Inhibitors of Protein–Protein Interaction with Capillary Electrophoresis Frontal Analysis
    Mei Xu, Chao Liu, Mi Zhou, Qing Li, Renxiao Wang, Jingwu Kang · 2016 · Analytical Chemistry
95. A Novel Long‐Range n to π* Interaction Secures the Smallest known α‐Helix in Water
    Huy N. Hoang, Chongyang Wu, Timothy A. Hill, Aline D. de Araujo, Paul V. Bernhardt, Ligong Liu, David P. Fairlie · 2019 · Angewandte Chemie International Edition
96. Structural development of stabilized helical peptides as inhibitors of estrogen receptor (ER)-mediated transcription
    Yosuke Demizu, Takashi Misawa, Takaya Nagakubo, Yasunari Kanda, Keiichiro Okuhira, Yuko Sekino, Mikihiko Naito, Masaaki Kurihara · 2015 · Bioorganic & Medicinal Chemistry
97. Phosphorylation of Capsaicinoid Derivatives Provides Highly Potent and Selective Inhibitors of the Transcription Factor STAT5b
    Nagarajan Elumalai, Angela Berg, Stefan Rubner, Thorsten Berg · 2015 · ACS Chemical Biology
98. Functional Disruption of the Cancer‐Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole Ligand
    Cecilia Vallet, Dennis Aschmann, Christine Beuck, Matthias Killa, Annika Meiners, Marcel Mertel, Martin Ehlers, Peter Bayer, Carsten Schmuck, Michael Giese et al. · 2020 · Angewandte Chemie International Edition
99. A Bionic‐Homodimerization Strategy for Optimizing Modulators of Protein–Protein Interactions: From Statistical Mechanics Theory to Potential Clinical Translation
    Jin Yan, Xiaoqiang Zheng, Weiming You, Wangxiao He, Guang‐Kui Xu · 2022 · Advanced Science
100. An In‐tether Chiral Center Modulates the Helicity, Cell Permeability, and Target Binding Affinity of a Peptide
     Kuan Hu, Hao Ran Geng, Qingzhou Zhang, Qisong Liu, Mingsheng Xie, Chengjie Sun, Wenjun Li, Huacan Lin, Fan Jiang, Tao Wang et al. · 2016 · Angewandte Chemie