Cited by 606Metalloenzymes and iron-sulfur proteinsEnzyme Structure and FunctionIron Metabolism and Disorders

Aconitase as iron–sulfur protein, enzyme, and iron-regulatory protein

Beinert, Helmut, Kennedy, Mary Claire, Stout, C. David·1996·Chemical Reviews

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAconitase as Iron−Sulfur Protein, Enzyme, and Iron-Regulatory ProteinHelmut Beinert, Mary Claire Kennedy, and C. David StoutView Author Information Institute for Enzyme Research, Graduate School, and Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin, Madison, Wisconsin 53705, Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, and Department of Molecular Biology, The Scripps Research Institute, La Jolla, California 92037 Cite this: Chem. Rev. 1996, 96, 7, 2335–2374Publication Date (Web):November 7, 1996Publication History Received21 February 1996Revised20 May 1996Published online7 November 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/cr950040zhttps://doi.org/10.1021/cr950040zresearch-articleACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views4873Altmetric-Citations499LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Cluster chemistry,Iron-sulfur clusters,Monomers,Peptides and proteins,Surface interactions Get e-Alerts

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177 of 177 references verified0 citation errors · 0 not checkable

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  • Mitochondrial aconitase is a ferrosulphoprotein in the mitochondrial matrix that catalyses reversible isomerisation of citrate to isocitrate via cis-aconitate in the Krebs cycle.

    “Mitochondrial aconitase is a ferrosulphoprotein located in the mitochondrial matrix that catalyses the reversible isomerisation of citrate to isocitrate via cis-aconitate in the Krebs cycle [111], Figure 44.”

Cites

Flagged first, then by citations

Research works printed but not linked: 18

  1. Dickman, S. R. The Enzymes ; Academic Press:  New York, 1961; p 495.
  2. Kennedy M. C. Ph.D., 1972, May
  3. Beinert, H.; Ruzicka, F. J.; Dreyer, J.L. Membrane Bioenergetics , Addison-Wesley:  Reading, MA, 1979; p 45.
  4. Spiro, T. G. Iron-Sulfur Proteins ; Wiley-Interscience:  New York, 1982.
  5. Rabinowitz J. C., 1972, Methods Enzymol., 24, 440
  6. Thomson A., 1985, J. Top. Mol. Struct. Biol., 6, 79
  7. Zheng L., 1992, J. Biol. Chem., 267, 7895, 10.1016/S0021-9258(18)42597-5 · DOI
  8. Hoffman B. M., 1985, J. Magn. Reson., 62, 537
  9. Lauble H., 1995, Proc. Natl. Acad. Sci. U.S.A.
  10. Peters R., 1954, Endeavour, 147
  11. Marais J. S. C., 1944, Vet. Sci. Anim. Ind., 20, 67
  12. Hodge, H. C.; Smith, F. A.; Chen, P. S. In Fluorine Chemistry ; Simons, J. H., Ed.; Academic Press:  New York, 1963; Vol. III, pp 1−25.
  13. Peters R. A., 1953, Proc. R. Soc. B., 140, 497
  14. Eanes R. Z., 1974, Mol. Pharm., 10, 130
  15. Rouault T. A., 1991, Cell, 64, 881, 10.1016/0092-8674(91)90312-M · DOI
  16. Haile D. J., 1989, Mol. Cell Biol., 9, 5055
  17. Pantopolous K., 1995, RNA, 1, 155
  18. Vanin A. F., 1995, Biochemistry (Moscow), 60, 225

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Authors
Beinert, H., Kennedy, M. C., & Stout, C. D.
Affiliations
Scripps Research Institute (US)
Venue
Chemical Reviews
Published
1996-01-01
Volume
96
Issue
7
Pages
2335-2374
ISSN
  • 0009-2665 (ISSN-L)
  • 1520-6890
OpenAlex
W2089119194
Cited by
606
References
177
Citations by year
2026: 9 · 2025: 14 · 2024: 20 · 2023: 24 · 2022: 22 · 2021: 17 · 2020: 16 · 2019: 24 · 2018: 11 · 2017: 14 · 2016: 28 · 2015: 22 · 2014: 25 · 2013: 19 · 2012: 22
FWCI
1.39
Type
journal article
Language
en
Open access
closed
Locations
  • Chemical Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Metalloenzymes and iron-sulfur proteins
  • Physical Sciences › Materials Science › Materials Chemistry › Enzyme Structure and Function
  • Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
Keywords
aconitase, iron-sulfur clusters, iron-sulfur proteins, iron regulation, iron regulatory proteins, enzyme mechanism, cluster chemistry

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