The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Global Synthesis and Critical Evaluation of Pharmaceutical Data Sets Collected from River Systems
Open accessAbstract
Pharmaceuticals have emerged as a major group of environmental contaminants over the past decade but relatively little is known about their occurrence in freshwaters compared to other pollutants. We present a global-scale analysis of the presence of 203 pharmaceuticals across 41 countries and show that contamination is extensive due to widespread consumption and subsequent disposal to rivers. There are clear regional biases in current understanding with little work outside North America, Europe, and China, and no work within Africa. Within individual countries, research is biased around a small number of populated provinces/states and the majority of research effort has focused upon just 14 compounds. Most research has adopted sampling techniques that are unlikely to provide reliable and representative data. This analysis highlights locations where concentrations of antibiotics, cardiovascular drugs, painkillers, contrast media, and antiepileptic drugs have been recorded well above thresholds known to cause toxic effects in aquatic biota. Studies of pharmaceutical occurrence and effects need to be seen as a global research priority due to increasing consumption, particularly among societies with aging populations. Researchers in all fields of environmental management need to work together more effectively to identify high risk compounds, improve the reliability and coverage of future monitoring studies, and develop new mitigation measures.
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Fragmentation and Flow Regulation of the World's Large River Systems
Nilsson, C., Reidy, C. A., Dynesius, M., & Revenga, C. (2005) · Science · doi:10.1126/science.1107887 · Cited by 3,509
Ecotoxicology of human pharmaceuticals
Fent, K., Weston, A. A., & Caminada, D. (2006) · Aquatic Toxicology · doi:10.1016/j.aquatox.2005.09.009 · Cited by 3,223
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Continental-Scale Effects of Nutrient Pollution on Stream Ecosystem Functioning
Woodward, G., Gessner, M. O., Giller, P. S., Gulis, V., Hladyz, S., Lecerf, A., Malmqvist, B., McKie, B. G., Tiegs, S. D., Cariss, H., et al. (2012) · Science · doi:10.1126/science.1219534 · Cited by 663
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Distributions of Pharmaceuticals in an Urban Estuary during both Dry- and Wet-Weather Conditions
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Cited by
Emerging threats and persistent conservation challenges for freshwater biodiversity
Reid, A. J., Carlson, A. K., Creed, I. F., Eliason, E. J., Gell, P. A., Johnson, P. T. J., Kidd, K. A., MacCormack, T. J., Olden, J. D., Ormerod, S. J., et al. (2019) · Biological Reviews · doi:10.1111/brv.12480 · Cited by 3,645
Patel, M., Kumar, R., Kishor, K., Mlsna, T., Pittman, C. U., & Mohan, D. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00299 · Cited by 2,654
Petrie, B., Barden, R., & Kasprzyk-Hordern, B. (2015) · Water Research · doi:10.1016/j.watres.2014.08.053 · Cited by 2,614
Pharmaceuticals and personal care products (PPCPs) in the freshwater aquatic environment
Ebele, A. J., Abou-Elwafa Abdallah, M., & Harrad, S. (2017) · Emerging Contaminants · doi:10.1016/j.emcon.2016.12.004 · Cited by 2,023
Pharmaceuticals in the environment-global occurrences and perspectives
aus der Beek, T., Weber, F.-A., Bergmann, A., Hickmann, S., Ebert, I., Hein, A., & Küster, A. (2015) · Environmental Toxicology and Chemistry · doi:10.1002/etc.3339 · Cited by 1,595
Metadata
- Authors
- Hughes, S. R., Kay, P., & Brown, L. E.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-12-20
- Volume
- 47
- Issue
- 2
- Pages
- 661-677
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2104105182
- Cited by
- 779
- References
- 9
- FWCI
- 21.15
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Hughes, S. R., Kay, P., & Brown, L. E. (2013). Global Synthesis and Critical Evaluation of Pharmaceutical Data Sets Collected from River Systems. Environmental Science & Technology. https://doi.org/10.1021/es3030148
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
