The DOI matches its Crossref record.
A New Method of Forming Peptide Bonds
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA New Method of Forming Peptide BondsJohn C. Sheehan and George P. HessCite this: J. Am. Chem. Soc. 1955, 77, 4, 1067–1068Publication Date (Print):February 1, 1955Publication History Published online1 May 2002Published inissue 1 February 1955https://pubs.acs.org/doi/10.1021/ja01609a099https://doi.org/10.1021/ja01609a099research-articleACS PublicationsRequest reuse permissionsArticle Views11307Altmetric-Citations1064LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
The preparation and properties of two new chromogenic substrates of trypsin
Erlanger, B. F., Kokowsky, N., & Cohen, W. (1961) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(61)90145-x · Cited by 3,353
Peptide Coupling Reagents, More than a Letter Soup
El-Faham, A., & Albericio, F. (2011) · Chemical Reviews · doi:10.1021/cr100048w · Cited by 1,245
Synthesis of Native Proteins by Chemical Ligation
Dawson, P. E., & Kent, S. B. H. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.923 · Cited by 1,082
Merrifield, B. (1986) · Science · doi:10.1126/science.3961484 · Cited by 1,005
Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals
Dunetz, J. R., Magano, J., & Weisenburger, G. A. (2016) · Organic Process Research & Development · doi:10.1021/op500305s · Cited by 819
Recent development of peptide coupling reagents in organic synthesis
Han, S.-Y., & Kim, Y.-A. (2004) · Tetrahedron · doi:10.1016/j.tet.2004.01.020 · Cited by 773
Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences
Coin, I., Beyermann, M., & Bienert, M. (2007) · Nature Protocols · doi:10.1038/nprot.2007.454 · Cited by 638
Solid-Phase Peptide Synthesis. III. An Improved Synthesis of Bradykinin*
Merrifield, R. B. (1964) · Biochemistry · doi:10.1021/bi00897a032 · Cited by 572
Merrifield, R. B. (1965) · Science · doi:10.1126/science.150.3693.178 · Cited by 540
Modified colorimetric ninhydrin methods for peptidase assay
Doi, E., Shibata, D., & Matoba, T. (1981) · Analytical Biochemistry · doi:10.1016/0003-2697(81)90175-5 · Cited by 476
Chemistry and Physiology of the Bound Auxins
Cohen, J. D., & Bandurski, R. S. (1982) · Annual Review of Plant Physiology · doi:10.1146/annurev.pp.33.060182.002155 · Cited by 474
Green metrics in mechanochemistry
Fantozzi, N., Volle, J.-N., Porcheddu, A., Virieux, D., García, F., & Colacino, E. (2023) · Chemical Society Reviews · doi:10.1039/d2cs00997h · Cited by 336
Soluble synthetic polymers as potential drug carriers
Duncan, R., & Kopeček, J. (1984) · Advances in Polymer Science · doi:10.1007/3-540-12796-8_10 · Cited by 318
The Synthesis of Ribonuclease A
Gutte, B., & Merrifield, R. B. (1971) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)62396-8 · Cited by 303
Ynamides as Racemization-Free Coupling Reagents for Amide and Peptide Synthesis
Hu, L., Xu, S., Zhao, Z., Yang, Y., Peng, Z., Yang, M., Wang, C., & Zhao, J. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b07230 · Cited by 267
Tengblad, A. (1979) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(79)90158-2 · Cited by 261
125I-labelled d(CH2)5[Tyr(Me)2,Thr4,Tyr-NH29]OVT: a selective oxytocin receptor ligand
Elands, J., Barberis, C., Jard, S., Tribollet, E., Dreifuss, J.-J., Bankowski, K., Manning, M., & Sawyer, W. H. (1988) · European Journal of Pharmacology · doi:10.1016/0014-2999(88)90778-9 · Cited by 245
Chemical, biochemical, functional, and nutritional characteristics of collagen in food systems
Asghar, A., & Henrickson, R. L. (1982) · Advances in Food Research · doi:10.1016/s0065-2628(08)60113-5 · Cited by 203
Ynamide Coupling Reagents: Origin and Advances
Hu, L., & Zhao, J. (2024) · Accounts of Chemical Research · doi:10.1021/acs.accounts.3c00743 · Cited by 89
“One such event occurred in 1955 when Arens and co-workers 22 introduced ethoxyacety-lene, a coupling reagent for peptide synthesis, at approximately the same time that the renowned dicyclohexylcarbodiimide 23 (DCC) coupling reagent was reported.”
BackgroundYnamide‐Mediated Peptide Bond Formation: Mechanistic Study and Synthetic Applications
Xu, S., Jiang, D., Peng, Z., Hu, L., Liu, T., Zhao, L., & Zhao, J. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202212247 · Cited by 46
The Formation of Peptide Bonds:A General Survey
JONES, J. H. (1979) · Major Methods of Peptide Bond Formation · doi:10.1016/b978-0-12-304201-9.50008-4 · Cited by 9
Metadata
- Authors
- Sheehan, J. C., & Hess, G. P.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 1955-02
- Volume
- 77
- Issue
- 4
- Pages
- 1067-1068
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W1986094359
- Cited by
- 1,265
- References
- 0
- FWCI
- 16.33
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.