The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
A Model for Describing the Thermodynamics of Multivalent Host−Guest Interactions at Interfaces
Open accessAbstract
A model has been described for interpreting the binding of multivalent molecules to interface-immobilized monovalent receptors through multiple, independent interactions. It is based on the concept of effective concentration, C(eff), which has been developed before for multivalent binding in solution and which incorporates effects of lengths and flexibilities of linkers between interacting sites. The model assumes: (i). the interactions are independent, (ii). the maximum number of interactions, p(max), is known, (iii). C(eff) is estimated from (simple) molecular models. Simulations of the thermodynamics and kinetics of multivalent host-guest binding to interfaces have been discussed, and competition with a monovalent competitor in solution has been incorporated as well. The model was successfully used to describe the binding of a divalent guest to self-assembled monolayers of a cyclodextrin host. The adsorption data of more complex guest-functionalized dendrimers, for which p(max) was not known beforehand, was interpreted as well. Finally, it has been shown that the model can aid to deconvolute contributions of multivalency and cooperativity to stability enhancements observed for the adsorption of multivalent molecules to interfaces.
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Cites
Comprehensive supramolecular chemistry
(1997) · Choice Reviews Online · doi:10.5860/choice.34-5097 · Cited by 6,476
Biological roles of oligosaccharides: all of the theories are correct
Varki, A. (1993) · Glycobiology · doi:10.1093/glycob/3.2.97 · Cited by 5,195
Mammen, M., Choi, S.-K., & Whitesides, G. M. (1998) · Angewandte Chemie International Edition · doi:10.1002/(sici)1521-3773(19981102)37:20<2754::aid-anie2754>3.0.co;2-3 · Cited by 4,110
Intracellular Functions of N-Linked Glycans
Helenius, A., & Aebi, A. M. (2001) · Science · doi:10.1126/science.291.5512.2364 · Cited by 2,405
Bertozzi, C. R., & Kiessling, A. L. L. (2001) · Science · doi:10.1126/science.1059820 · Cited by 1,939
Lundquist, J. J., & Toone, E. J. (2002) · Chemical Reviews · doi:10.1021/cr000418f · Cited by 1,576
Über die Gestalt fadenförmiger Moleküle in Lösungen
Kuhn, W. (1934) · Kolloid-Zeitschrift · doi:10.1007/bf01451681 · Cited by 1,091
On the attribution and additivity of binding energies
Jencks, W. P. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.7.4046 · Cited by 912
Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands
Kitov, P. I., Sadowska, J. M., Mulvey, G., Armstrong, G. D., Ling, H., Pannu, N. S., Read, R. J., & Bundle, D. R. (2000) · Nature · doi:10.1038/35001095 · Cited by 869
Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture
Gestwicki, J. E., Cairo, C. W., Strong, L. E., Oetjen, K. A., & Kiessling, L. L. (2002) · Journal of the American Chemical Society · doi:10.1021/ja027184x · Cited by 706
Synthetic multivalent ligands in the exploration of cell-surface interactions
Kiessling, L. (2000) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(00)00153-8 · Cited by 544
Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor
Kato, Y., Tapping, R. I., Huang, S., Watson, M. H., Ulevitch, R. J., & Lee, J.-D. (1998) · Nature · doi:10.1038/27234 · Cited by 436
Control of Multivalent Interactions by Binding Epitope Density
Cairo, C. W., Gestwicki, J. E., Kanai, M., & Kiessling, L. L. (2002) · Journal of the American Chemical Society · doi:10.1021/ja016727k · Cited by 383
Sigal, G. B., Mammen, M., Dahmann, G., & Whitesides, G. M. (1996) · Journal of the American Chemical Society · doi:10.1021/ja953729u · Cited by 338
Assessment of Cooperativity in Self-Assembly
Ercolani, G. (2003) · Journal of the American Chemical Society · doi:10.1021/ja038396c · Cited by 309
Kanai, M., Mortell, K. H., & Kiessling, L. L. (1997) · Journal of the American Chemical Society · doi:10.1021/ja972089n · Cited by 297
Spanning binding sites on allosteric proteins with polymer-linked ligand dimers
Kramer, R. H., & Karpen, J. W. (1998) · Nature · doi:10.1038/27227 · Cited by 278
Parallel Synthesis and Screening of a Solid Phase Carbohydrate Library
Liang, R., Yan, L., Loebach, J., Ge, M., Uozumi, Y., Sekanina, K., Horan, N., Gildersleeve, J., Thompson, C., Smith, A., et al. (1996) · Science · doi:10.1126/science.274.5292.1520 · Cited by 277
Inter-receptor communication through arrays of bacterial chemoreceptors
Gestwicki, J. E., & Kiessling, L. L. (2002) · Nature · doi:10.1038/415081a · Cited by 254
Two-component regulator of Enterococcus faecalis cytolysin responds to quorum-sensing autoinduction
Haas, W., Shepard, B. D., & Gilmore, M. S. (2002) · Nature · doi:10.1038/415084a · Cited by 246
How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis
Glynne, R., Akkaraju, S., Healy, J. I., Rayner, J., Goodnow, C. C., & Mack, D. H. (2000) · Nature · doi:10.1038/35001102 · Cited by 210
Nonstatistical binding of a protein to clustered carbohydrates
Horan, N., Yan, L., Isobe, H., Whitesides, G. M., & Kahne, D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.21.11782 · Cited by 203
Ercolani, G., Mandolini, L., Mencarelli, P., & Roelens, S. (1993) · Journal of the American Chemical Society · doi:10.1021/ja00063a008 · Cited by 191
Multisite Inclusion Complexation of Redox Active Dendrimer Guests
Castro, R., Cuadrado, I., Alonso, B., Casado, C. M., Morán, M., & Kaifer, A. E. (1997) · Journal of the American Chemical Society · doi:10.1021/ja970922a · Cited by 166
Model and Simulation of Multivalent Binding to Fixed Ligands
Müller, K. M., Arndt, K. M., & Plückthun, A. (1998) · Analytical Biochemistry · doi:10.1006/abio.1998.2725 · Cited by 143
Mulder, A., Auletta, T., Sartori, A., Ciotto, S. D., Casnati, A., Ungaro, R., Huskens, J., & Reinhoudt, D. N. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0317168 · Cited by 137
Self-citationSynthetic polymeric sialoside inhibitors of influenza virus receptor‐binding activity
Matrosovich, M. N., Mochalova, L. V., Vp, M., Byramova, N. E., & Bovin, N. V. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)80486-3 · Cited by 134
Ligand recognition by influenza virus. The binding of bivalent sialosides.
Glick, G. D., Toogood, P. L., Wiley, D. C., Skehel, J. J., & Knowles, J. R. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54335-0 · Cited by 113
Physical Basis of Self-Assembly Macrocyclizations
Ercolani, G. (1998) · The Journal of Physical Chemistry B · doi:10.1021/jp9816723 · Cited by 109
Tuning chemotactic responses with synthetic multivalent ligands
Gestwicki, J. E., Strong, L. E., & Kiessling, L. L. (2000) · Chemistry & Biology · doi:10.1016/s1074-5521(00)00002-8 · Cited by 97
Metallo, S. J., Kane, R. S., Holmlin, R. E., & Whitesides, G. M. (2003) · Journal of the American Chemical Society · doi:10.1021/ja030045a · Cited by 92
Carbon-13 NMR of glycogen: hydration response studied by using solids methods
Jackson, C. L., & Bryant, R. G. (1989) · Biochemistry · doi:10.1021/bi00438a018 · Cited by 29
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Bishop, K. J. M., Wilmer, C. E., Soh, S., & Grzybowski, B. A. (2009) · Small · doi:10.1002/smll.200900358 · Cited by 1,521
Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands
Cecioni, S., Imberty, A., & Vidal, S. (2015) · Chemical Reviews · doi:10.1021/cr500303t · Cited by 544
Metadata
- Authors
- Huskens, J., Mulder, A., Auletta, T., Nijhuis, C. A., Ludden, M. J. W., & Reinhoudt, D. N.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-05-07
- Volume
- 126
- Issue
- 21
- Pages
- 6784-6797
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2167813002
- Cited by
- 257
- References
- 32
- FWCI
- 12.50
- Type
- journal article
- Language
- en
- Open access
- green
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