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Cited by 187

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Facile Surface Functionalization of Hydrophobic Magnetic Nanoparticles

Open access
Liu, Yuan, Chen, Tao, Wu, Cuichen, Qiu, Liping, Hu, Rong, Li, Juan, Cansiz, Sena, Zhang, Liqin, Cui, Cheng, Zhu, Guizhi, You, Mingxu, Zhang, Tao, Tan, Weihong·2014·Journal of the American Chemical Society

Abstract

Nonpolar phase synthesized hydrophobic nanocrystals show attractive properties and have demonstrated prominent potential in biomedical applications. However, the preparation of biocompatible nanocrystals is made difficult by the presence of hydrophobic surfactant stabilizer on their surfaces. To address this limitation, we have developed a facile, high efficiency, single-phase and low-cost method to convert hydrophobic magnetic nanoparticles (MNPs) to an aqueous phase using tetrahydrofuran, NaOH and 3,4-dihydroxyhydrocinnamic acid without any complicated organic synthesis. The as-transferred hydrophilic MNPs are water-soluble over a wide pH range (pH = 3-12), and the solubility is pH-controllable. Furthermore, the as-transferred MNPs with carboxylate can be readily adapted with further surface functionalization, varying from small molecule dyes to oligonucleotides and enzymes. Finally, the strategy developed here can easily be extended to other types of hydrophobic nanoparticles to facilitate biomedical applications of nanomaterials.

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Crossref · 10.1021/ja5060324

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Metadata

Authors
Liu, Y., Chen, T., Wu, C., Qiu, L., Hu, R., Li, J., Cansiz, S., Zhang, L., Cui, C., Zhu, G., You, M., Zhang, T., & Tan, W.
Venue
Journal of the American Chemical Society
Published
2014-08-28
Volume
136
Issue
36
Pages
12552-12555
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2321197535
Cited by
187
References
2
FWCI
8.77
Type
journal article
Language
en
Open access
hybrid

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