The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
A Targetable Fluorescent Probe for Imaging Hydrogen Peroxide in the Mitochondria of Living Cells
Open accessAbstract
We present the design, synthesis, and biological applications of mitochondria peroxy yellow 1 (MitoPY1), a new type of bifunctional fluorescent probe for imaging hydrogen peroxide levels within the mitochondria of living cells. MitoPY1 combines a chemoselective boronate-based switch and a mitochondrial-targeting phosphonium moiety for detection of hydrogen peroxide localized to cellular mitochondria. Confocal microscopy and flow cytometry experiments in a variety of mammalian cell types show that MitoPY1 can visualize localized changes in mitochondrial hydrogen peroxide concentrations generated by situations of oxidative stress.
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Mitochondrial Dysfunction and Oxidative Stress in Neurodegenerative Diseases
Lin, M. T., & Beal, M. F. (2006) · Nature · doi:10.1038/nature05292 · Cited by 6,455
Neurodegenerative diseases and oxidative stress
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ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
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H 2 O 2 , a Necessary Evil for Cell Signaling
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Targeting Antioxidants to Mitochondria by Conjugation to Lipophilic Cations
Murphy, M. P., & Smith, R. A. J. (2007) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.47.120505.105110 · Cited by 1,173
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Selective fluorescent imaging of superoxide in vivo using ethidium-based probes
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Chemistry and biology of reactive oxygen species in signaling or stress responses
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Zielonka, J., Joseph, J., Sikora, A., Hardy, M., Ouari, O., Vasquez-Vivar, J., Cheng, G., Lopez, M., & Kalyanaraman, B. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00042 · Cited by 1,683
Unraveling the biological roles of reactive oxygen species
Murphy, M. P., Holmgren, A., Larsson, N.-G., Halliwell, B., Chang, C. J., Kalyanaraman, B., Rhee, S. G., Thornalley, P. J., Partridge, L., Gems, D., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.03.010 · Cited by 836
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Metadata
- Authors
- Dickinson, B. C., & Chang, C. J.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-07-01
- Volume
- 130
- Issue
- 30
- Pages
- 9638-9639
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2081589302
- Cited by
- 642
- References
- 9
- FWCI
- 11.41
- Type
- journal article
- Language
- en
- Open access
- green
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