The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Electrostatically Mediated Liposome Fusion and Lipid Exchange with a Nanoparticle-Supported Bilayer for Control of Surface Charge, Drug Containment, and Delivery
Open accessAbstract
The loading and containment of cargo within nanoparticles and their efficient delivery to cells represent a primary challenge in nanomedicine. We report lipid exchange between free and mesoporous silica nanoparticle-supported lipid bilayers as an effective means of containing cargo, controlling charge, and directing delivery to mammalian cells. The delivery of a membrane-impermeable dye (calcein) and a chemotherapeutic drug (doxorubicin) are demonstrated. Exchanged lipid bilayers minimized premature drug release, and an overall positive charge on the supported lipid bilayer effected enhanced delivery.
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Cites
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Metadata
- Authors
- Liu, J., Jiang, X., Ashley, C., & Brinker, C. J.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-05-15
- Volume
- 131
- Issue
- 22
- Pages
- 7567-7569
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W1998781337
- Cited by
- 277
- References
- 27
- FWCI
- 9.02
- Type
- journal article
- Language
- en
- Open access
- green
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