The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
FePt Nanoparticles as an Fe Reservoir for Controlled Fe Release and Tumor Inhibition
Open accessAbstract
Chemically disordered face centered cubic (fcc) FePt nanoparticles (NPs) show the controlled release of Fe in low pH solution. The released Fe catalyzes H(2)O(2) decomposition into reactive oxygen species within cells, causing fast oxidation and deterioration of cellular membranes. Functionalized with luteinizing hormone-releasing hormone (LHRH) peptide via phospholipid, the fcc-FePt NPs can bind preferentially to the human ovarian cancer cell line (A2780) that overexpresses LHRH receptors and exhibit high toxicity to these tumor cells. In contrast, the fcc-FePt NPs pre-etched in the low pH (4.8) buffer solution show nonappreciable cytotoxicity. The work demonstrates that fcc-FePt NPs may function as a new type of agent for controlled cancer therapy.
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Cites
Monodisperse FePt Nanoparticles and Ferromagnetic FePt Nanocrystal Superlattices
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Cited by
Kittler, S., Greulich, C., Diendorf, J., Köller, M., & Epple, M. (2010) · Chemistry of Materials · doi:10.1021/cm100023p · Cited by 1,126
Tuning Nanoparticle Catalysis for the Oxygen Reduction Reaction
Guo, S., Zhang, S., & Sun, S. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201207186 · Cited by 994
Self-citationEnzyme Mimicry for Combating Bacteria and Biofilms
Chen, Z., Wang, Z., Ren, J., & Qu, X. (2018) · Accounts of Chemical Research · doi:10.1021/acs.accounts.8b00011 · Cited by 499
Figuerola, A., Di Corato, R., Manna, L., & Pellegrino, T. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2009.12.012 · Cited by 480
New forms of superparamagnetic nanoparticles for biomedical applications
Xu, C., & Sun, S. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.10.008 · Cited by 349
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Metadata
- Authors
- Xu, C., Yuan, Z., Kohler, N., Kim, J., Chung, M. A., & Sun, S.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-10-01
- Volume
- 131
- Issue
- 42
- Pages
- 15346-15351
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2063576239
- Cited by
- 201
- References
- 7
- FWCI
- 8.15
- Type
- journal article
- Language
- en
- Open access
- green
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