The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Nanoscale Metal–Organic Frameworks for Ratiometric Oxygen Sensing in Live Cells
Open accessAbstract
We report the design of a phosphorescence/fluorescence dual-emissive nanoscale metal-organic framework (NMOF), R-UiO, as an intracellular oxygen (O2) sensor. R-UiO contains a Pt(II)-porphyrin ligand as an O2-sensitive probe and a Rhodamine-B isothiocyanate ligand as an O2-insensitive reference probe. It exhibits good crystallinity, high stability, and excellent ratiometric luminescence response to O2 partial pressure. In vitro experiments confirmed the applicability of R-UiO as an intracellular O2 biosensor. This work is the first report of a NMOF-based intracellular oxygen sensor and should inspire the design of ratiometric NMOF sensors for other important analytes in biological systems.
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Cited by
Luminescent sensors based on metal-organic frameworks
Zhang, Y., Yuan, S., Day, G., Wang, X., Yang, X., & Zhou, H.-C. (2018) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2017.06.007 · Cited by 1,255
Ratiometric optical nanoprobes enable accurate molecular detection and imaging
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Self-citationMultifunctional metal–organic framework heterostructures for enhanced cancer therapy
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Metadata
- Authors
- Xu, R., Wang, Y., Duan, X., Lu, K., Micheroni, D., Hu, A., & Lin, W.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-02-16
- Volume
- 138
- Issue
- 7
- Pages
- 2158-2161
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2278059930
- Cited by
- 319
- References
- 36
- FWCI
- 18.04
- Type
- journal article
- Language
- en
- Open access
- green
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- Xu, R., Wang, Y., Duan, X., Lu, K., Micheroni, D., Hu, A., & Lin, W. (2016). Nanoscale Metal–Organic Frameworks for Ratiometric Oxygen Sensing in Live Cells. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.5b13458
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