The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Encapsulation of a Nerve Agent Detoxifying Enzyme by a Mesoporous Zirconium Metal–Organic Framework Engenders Thermal and Long-Term Stability
Abstract
Immobilized enzymes typically have greater thermal and operational stability than their soluble form. Here we report that for the first time, a nerve agent detoxifying enzyme, organophosphorus acid anhydrolase (OPAA), has been successfully encapsulated into a water-stable zirconium metal-organic framework (MOF). This MOF features a hierarchical mesoporous channel structure and exhibits a 12 wt % loading capacity of OPAA. The thermal and long-term stabilities of OPAA are both significantly enhanced after immobilization.
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Cites
The Chemistry and Applications of Metal-Organic Frameworks
Furukawa, H., Cordova, K. E., O’Keeffe, M., & Yaghi, O. M. (2013) · Science · doi:10.1126/science.1230444 · Cited by 16,945
Water Adsorption in Porous Metal–Organic Frameworks and Related Materials
Furukawa, H., Gándara, F., Zhang, Y.-B., Jiang, J., Queen, W. L., Hudson, M. R., & Yaghi, O. M. (2014) · Journal of the American Chemical Society · doi:10.1021/ja500330a · Cited by 2,888
Water Stability and Adsorption in Metal–Organic Frameworks
Burtch, N. C., Jasuja, H., & Walton, K. S. (2014) · Chemical Reviews · doi:10.1021/cr5002589 · Cited by 2,730
Reticular Chemistry: Occurrence and Taxonomy of Nets and Grammar for the Design of Frameworks
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Large-Pore Apertures in a Series of Metal-Organic Frameworks
Deng, H., Grunder, S., Cordova, K. E., Valente, C., Furukawa, H., Hmadeh, M., Gándara, F., Whalley, A. C., Liu, Z., Asahina, S., et al. (2012) · Science · doi:10.1126/science.1220131 · Cited by 2,126
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Vapor-Phase Metalation by Atomic Layer Deposition in a Metal–Organic Framework
Mondloch, J. E., Bury, W., Fairen-Jimenez, D., Kwon, S., DeMarco, E. J., Weston, M. H., Sarjeant, A. A., Nguyen, S. T., Stair, P. C., Snurr, R. Q., et al. (2013) · Journal of the American Chemical Society · doi:10.1021/ja4050828 · Cited by 1,008
Self-citationDestruction of chemical warfare agents using metal–organic frameworks
Mondloch, J. E., Katz, M. J., Isley III, W. C., Ghosh, P., Liao, P., Bury, W., Wagner, G. W., Hall, M. G., DeCoste, J. B., Peterson, G. W., et al. (2015) · Nature Materials · doi:10.1038/nmat4238 · Cited by 967
Self-citationSynthesis, Structure, and Metalation of Two New Highly Porous Zirconium Metal–Organic Frameworks
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Cited by
Li, D., Yadav, A., Zhou, H., Roy, K., Thanasekaran, P., & Lee, C. (2024) · Global Challenges · doi:10.1002/gch2.202300244 · Cited by 437
Shielding against Unfolding by Embedding Enzymes in Metal–Organic Frameworks via a de Novo Approach
Liao, F.-S., Lo, W.-S., Hsu, Y.-S., Wu, C.-C., Wang, S.-C., Shieh, F.-K., Morabito, J. V., Chou, L.-Y., Wu, K. C.-W., & Tsung, C.-K. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b01794 · Cited by 382
Incorporation of biomolecules in Metal-Organic Frameworks for advanced applications
An, H., Li, M., Gao, J., Zhang, Z., Ma, S., & Chen, Y. (2019) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2019.01.001 · Cited by 336
Metadata
- Authors
- Li, P., Moon, S.-Y., Guelta, M. A., Harvey, S. P., Hupp, J. T., & Farha, O. K.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-06-24
- Volume
- 138
- Issue
- 26
- Pages
- 8052-8055
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2466291603
- Cited by
- 365
- References
- 23
- FWCI
- 21.52
- Type
- journal article
- Language
- en
- Open access
- closed
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- Li, P., Moon, S.-Y., Guelta, M. A., Harvey, S. P., Hupp, J. T., & Farha, O. K. (2016). Encapsulation of a Nerve Agent Detoxifying Enzyme by a Mesoporous Zirconium Metal–Organic Framework Engenders Thermal and Long-Term Stability. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.6b03673
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