The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Molecular Imprinting on Inorganic Nanozymes for Hundred-fold Enzyme Specificity
Abstract
Enzyme-mimicking nanomaterials (nanozymes) are more cost-effective and robust than protein enzymes, but they lack specificity. Herein, molecularly imprinted polymers were grown on Fe 3 O 4 nanozymes with peroxidase-like activity to create substrate binding pockets. Electron microscopy confirmed a shell of nanogel. By imprinting with an adsorbed substrate, moderate specificity was achieved with neutral monomers. Further introducing charged monomers led to nearly 100-fold specificity for the imprinted substrate over the nonimprinted compared to that of bare Fe 3 O 4 . Selective substrate binding was further confirmed by isothermal titration calorimetry. The same method was also successfully applied for imprinting on gold nanoparticles (peroxidase mimics) and nanoceria (oxidase mimics). Molecular imprinting furthers the functional enzyme mimicking aspect of nanozymes, and such hybrid materials will find applications in biosensor development, separation, environmental remediation, and drug delivery.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.260 · Cited by 7,483
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
Wei, H., & Wang, E. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35486e · Cited by 3,779
Wulff, G. (1995) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199518121 · Cited by 2,373
Molecularly Imprinted Polymers and Their Use in Biomimetic Sensors
Haupt, K., & Mosbach, K. (2000) · Chemical Reviews · doi:10.1021/cr990099w · Cited by 2,286
Chen, L., Xu, S., & Li, J. (2011) · Chemical Society Reviews · doi:10.1039/c0cs00084a · Cited by 1,753
Superoxide dismutase mimetic properties exhibited by vacancy engineered ceria nanoparticles
Korsvik, C., Patil, S., Seal, S., & Self, W. T. (2007) · Chemical Communications · doi:10.1039/b615134e · Cited by 1,278
Catalytically Active Nanomaterials: A Promising Candidate for Artificial Enzymes
Lin, Y., Ren, J., & Qu, X. (2014) · Accounts of Chemical Research · doi:10.1021/ar400250z · Cited by 1,252
Nanoceria exhibit redox state-dependent catalase mimetic activity
Pirmohamed, T., Dowding, J. M., Singh, S., Wasserman, B., Heckert, E., Karakoti, A. S., King, J. E. S., Seal, S., & Self, W. T. (2010) · Chemical Communications · doi:10.1039/b922024k · Cited by 1,214
Oxidase‐Like Activity of Polymer‐Coated Cerium Oxide Nanoparticles
Asati, A., Santra, S., Kaittanis, C., Nath, S., & Perez, J. M. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200805279 · Cited by 1,161
Pharmacological potential of cerium oxide nanoparticles
Celardo, I., Pedersen, J. Z., Traversa, E., & Ghibelli, L. (2011) · Nanoscale · doi:10.1039/c0nr00875c · Cited by 1,151
Cited by
Nanozymes: A clear definition with fuzzy edges
Wei, H., Gao, L., Fan, K., Liu, J., He, J., Qu, X., Dong, S., Wang, E., & Yan, X. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101269 · Cited by 580
Self-citationEnzyme Mimicry for Combating Bacteria and Biofilms
Chen, Z., Wang, Z., Ren, J., & Qu, X. (2018) · Accounts of Chemical Research · doi:10.1021/acs.accounts.8b00011 · Cited by 499
Nanozymes: Activity origin, catalytic mechanism, and biological application
Yang, W., Yang, X., Zhu, L., Chu, H., Li, X., & Xu, W. (2021) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2021.214170 · Cited by 470
Nanozyme for tumor therapy: Surface modification matters
Tang, G., He, J., Liu, J., Yan, X., & Fan, K. (2021) · Exploration · doi:10.1002/exp.20210005 · Cited by 441
Self-citationMetal–organic framework based nanozymes: promising materials for biochemical analysis
Niu, X., Li, X., Lyu, Z., Pan, J., Ding, S., Ruan, X., Zhu, W., Du, D., & Lin, Y. (2020) · Chemical Communications · doi:10.1039/d0cc04890a · Cited by 328
Metadata
- Authors
- Zhang, Z., Zhang, X., Liu, B., & Liu, J.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-04-05
- Volume
- 139
- Issue
- 15
- Pages
- 5412-5419
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2598282456
- Cited by
- 666
- References
- 50
- FWCI
- 29.25
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Molecular Imprinting on Inorganic Nanozymes for Hundred-fold Enzyme Specificity. https://app.cochat.ai/papers/10.1021/jacs.7b00601
- The paper
- Zhang, Z., Zhang, X., Liu, B., & Liu, J. (2017). Molecular Imprinting on Inorganic Nanozymes for Hundred-fold Enzyme Specificity. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.7b00601
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
