The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Continuous O2-Evolving MnFe2O4 Nanoparticle-Anchored Mesoporous Silica Nanoparticles for Efficient Photodynamic Therapy in Hypoxic Cancer
Abstract
Therapeutic effects of photodynamic therapy (PDT) are limited by cancer hypoxia because the PDT process is dependent on O 2 concentration. Herein, we design biocompatible manganese ferrite nanoparticle-anchored mesoporous silica nanoparticles (MFMSNs) to overcome hypoxia, consequently enhancing the therapeutic efficiency of PDT. By exploiting the continuous O 2 -evolving property of MnFe 2 O 4 nanoparticles through the Fenton reaction, MFMSNs relieve hypoxic condition using a small amount of nanoparticles and improve therapeutic outcomes of PDT for tumors in vivo . In addition, MFMSNs exhibit T 2 contrast effect in magnetic resonance imaging (MRI), allowing in vivo tracking of MFMSNs. These findings demonstrate great potential of MFMSNs for theranostic agents in cancer therapy.
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The Fenton Reaction. Dependence of the Rate on pH
Kremer, M. L. (2003) · The Journal of Physical Chemistry A · doi:10.1021/jp020654p · Cited by 197
Cited by
Yunna, C., Mengru, H., Lei, W., & Weidong, C. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173090 · Cited by 2,454
Metal–organic framework-derived porous materials for catalysis
Chen, Y.-Z., Zhang, R., Jiao, L., & Jiang, H.-L. (2018) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2018.02.008 · Cited by 1,015
Fu, L., Wan, Y., Qi, C., He, J., Li, C., Yang, C., Xu, H., Lin, J., & Huang, P. (2021) · Advanced Materials · doi:10.1002/adma.202006892 · Cited by 820
Nanoparticle-triggered in situ catalytic chemical reactions for tumour-specific therapy
Lin, H., Chen, Y., & Shi, J. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00471k · Cited by 803
Conquering the Hypoxia Limitation for Photodynamic Therapy
Wan, Y., Fu, L., Li, C., Lin, J., & Huang, P. (2021) · Advanced Materials · doi:10.1002/adma.202103978 · Cited by 705
Metadata
- Authors
- Kim, J., Cho, H. R., Jeon, H., Kim, D., Song, C., Lee, N., Choi, S. H., & Hyeon, T.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-08-03
- Volume
- 139
- Issue
- 32
- Pages
- 10992-10995
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2737866071
- Cited by
- 707
- References
- 4
- FWCI
- 36.20
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kim, J., Cho, H. R., Jeon, H., Kim, D., Song, C., Lee, N., Choi, S. H., & Hyeon, T. (2017). Continuous O2-Evolving MnFe2O4 Nanoparticle-Anchored Mesoporous Silica Nanoparticles for Efficient Photodynamic Therapy in Hypoxic Cancer. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.7b05559
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