The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Iron Chelation by the Powerful Antioxidant Flavonoid Quercetin
Abstract
Chelation of the bare and hydrated iron(II) cation by quercetin has been investigated at the DF/B3LYP level in the gas phase. Several complexed species arising from neutral and anionic forms of the ligand have been taken into account. Both 1:1 and 1:2 metal/flavonoid stoichiometries have been considered. Results indicate that among the potential sites of chelation present on quercetin, the oxygen atoms belonging to the 3-hydroxy and 4-oxo, and to the 5-hydroxy and 4-oxo groups, are the preferred ones. Time-dependent density functional theory (TDDFT) calculations, used to reproduce the electronic UV-vis spectra of isolated quercetin and its complexes with Fe2+, were also performed in methanol and dimethylsulfoxide.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Density-functional thermochemistry. III. The role of exact exchange
Becke, A. D. (1993) · The Journal of Chemical Physics · doi:10.1063/1.464913 · Cited by 103,767
Lee, C., Yang, W., & Parr, R. G. (1988) · Physical Review B · doi:10.1103/physrevb.37.785 · Cited by 100,874
Hehre, W. J., Ditchfield, R., & Pople, J. A. (1972) · The Journal of Chemical Physics · doi:10.1063/1.1677527 · Cited by 15,855
Hay, P. J., & Wadt, W. R. (1985) · The Journal of Chemical Physics · doi:10.1063/1.448975 · Cited by 15,577
Ditchfield, R., Hehre, W. J., & Pople, J. A. (1971) · The Journal of Chemical Physics · doi:10.1063/1.1674902 · Cited by 10,612
Miertuš, S., Scrocco, E., & Tomasi, J. (1981) · Chemical Physics · doi:10.1016/0301-0104(81)85090-2 · Cited by 8,937
Ab initio study of solvated molecules: a new implementation of the polarizable continuum model
Cossi, M., Barone, V., Cammi, R., & Tomasi, J. (1996) · Chemical Physics Letters · doi:10.1016/0009-2614(96)00349-1 · Cited by 3,440
Miertus̃, S., & Tomasi, J. (1982) · Chemical Physics · doi:10.1016/0301-0104(82)85072-6 · Cited by 2,475
Barone, V., Cossi, M., & Tomasi, J. (1997) · The Journal of Chemical Physics · doi:10.1063/1.474671 · Cited by 2,406
Accuracy of AHnequilibrium geometries by single determinant molecular orbital theory
Hariharan, P. C., & Pople, J. A. (1974) · Molecular Physics · doi:10.1080/00268977400100171 · Cited by 2,307
Cited by
Oxidative Stress: Harms and Benefits for Human Health
Pizzino, G., Irrera, N., Cucinotta, M., Pallio, G., Mannino, F., Arcoraci, V., Squadrito, F., Altavilla, D., & Bitto, A. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/8416763 · Cited by 4,837
Yeshi, K., Crayn, D., Ritmejerytė, E., & Wangchuk, P. (2022) · Molecules · doi:10.3390/molecules27010313 · Cited by 488
RETRACTED: Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
Slika, H., Mansour, H., Wehbe, N., Nasser, S. A., Iratni, R., Nasrallah, G., Shaito, A., Ghaddar, T., Kobeissy, F., & Eid, A. H. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112442 · Cited by 441
“Chelation is thought to be preferred at the 5-hydroxyl and 4-carbonyl sites as it forms a six-membered ring conveying greater stability [58,59].”
BackgroundRetractedJahan, M. S., Guo, S., Baloch, A. R., Sun, J., Shu, S., Wang, Y., Ahammed, G. J., Kabir, K., & Roy, R. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.110593 · Cited by 365
Alberto, M. E., Russo, N., Grand, A., & Galano, A. (2013) · Physical Chemistry Chemical Physics · doi:10.1039/c3cp43319f · Cited by 288
Self-citation
Metadata
- Authors
- Leopoldini, M., Russo, N., Chiodo, S., & Toscano, M.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-08-01
- Volume
- 54
- Issue
- 17
- Pages
- 6343-6351
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W1981017880
- Cited by
- 484
- References
- 51
- FWCI
- 7.38
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Iron Chelation by the Powerful Antioxidant Flavonoid Quercetin. https://app.cochat.ai/papers/10.1021/jf060986h
- The paper
- Leopoldini, M., Russo, N., Chiodo, S., & Toscano, M. (2006). Iron Chelation by the Powerful Antioxidant Flavonoid Quercetin. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf060986h
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
