The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Identification of Anthocyanins in the Liver, Eye, and Brain of Blueberry-Fed Pigs
Abstract
Dietary intervention with anthocyanins may confer benefits in brain function, including vision. Research to date indicates that animals have only a limited capacity to absorb anthocyanins, compared to other types of flavonoids. Pigs, which are a suitable model for human digestive absorption, were used to examine the deposition of anthocyanins in tissues including the liver, eye, and brain tissue. Pigs were fed diets supplemented with 0, 1, 2, or 4% w/w blueberries ( Vaccinium corymbosum L. 'Jersey') for 4 weeks. Prior to euthanasia, pigs were fasted for 18-21 h. Although no anthocyanins were detected in the plasma or urine of the fasted animals, intact anthocyanins were detected in all tissues where they were sought. LC-MS/MS results are presented for the relative concentration of 11 intact anthocyanins in the liver, eye, cortex, and cerebellum. The results suggest that anthocyanins can accumulate in tissues, including tissues beyond the blood-brain barrier.
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Cites
Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents
Singleton, V. L., & Rossi, J. A. (1965) · American Journal of Enology and Viticulture · doi:10.5344/ajev.1965.16.3.144 · Cited by 24,852
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
Manach, C., Williamson, G., Morand, C., Scalbert, A., & Rémésy, C. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.230s · Cited by 4,219
Cited by
Del Rio, D., Rodriguez-Mateos, A., Spencer, J. P. E., Tognolini, M., Borges, G., & Crozier, A. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4581 · Cited by 2,601
Anthocyanins: Natural Colorants with Health-Promoting Properties
He, J., & Giusti, M. M. (2010) · Annual Review of Food Science and Technology · doi:10.1146/annurev.food.080708.100754 · Cited by 1,637
Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action
Vauzour, D., Rodriguez-Mateos, A., Corona, G., Oruna-Concha, M. J., & Spencer, J. P. E. (2010) · Nutrients · doi:10.3390/nu2111106 · Cited by 855
Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
Kalt, W., Cassidy, A., Howard, L. R., Krikorian, R., Stull, A. J., Tremblay, F., & Zamora-Ros, R. (2020) · Advances in Nutrition · doi:10.1093/advances/nmz065 · Cited by 659
Self-citationBlueberry supplementation improves memory in older adults
Krikorian, R., Shidler, M. D., Nash, T. A., Kalt, W., Vinqvist-Tymchuk, M. R., Shukitt-Hale, B., & Joseph, J. A. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9029332 · Cited by 582
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Metadata
- Authors
- Kalt, W., Blumberg, J. B., McDonald, J. E., Vinqvist-Tymchuk, M. R., Fillmore, S. A. E., Graf, B. A., O’Leary, J. M., & Milbury, P. E.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-02
- Volume
- 56
- Issue
- 3
- Pages
- 705-712
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W1973621432
- Cited by
- 336
- References
- 2
- FWCI
- 9.66
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kalt, W., Blumberg, J. B., McDonald, J. E., Vinqvist-Tymchuk, M. R., Fillmore, S. A. E., Graf, B. A., O’Leary, J. M., & Milbury, P. E. (2008). Identification of Anthocyanins in the Liver, Eye, and Brain of Blueberry-Fed Pigs. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf071998l
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