The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Identification of Anthocyanins in the Liver, Eye, and Brain of Blueberry-Fed Pigs
Abstract
Dietary intervention with anthocyanins may confer benefits in brain function, including vision. Research to date indicates that animals have only a limited capacity to absorb anthocyanins, compared to other types of flavonoids. Pigs, which are a suitable model for human digestive absorption, were used to examine the deposition of anthocyanins in tissues including the liver, eye, and brain tissue. Pigs were fed diets supplemented with 0, 1, 2, or 4% w/w blueberries ( Vaccinium corymbosum L. 'Jersey') for 4 weeks. Prior to euthanasia, pigs were fasted for 18-21 h. Although no anthocyanins were detected in the plasma or urine of the fasted animals, intact anthocyanins were detected in all tissues where they were sought. LC-MS/MS results are presented for the relative concentration of 11 intact anthocyanins in the liver, eye, cortex, and cerebellum. The results suggest that anthocyanins can accumulate in tissues, including tissues beyond the blood-brain barrier.
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Cites
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Cited by
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He, J., & Giusti, M. M. (2010) · Annual Review of Food Science and Technology · doi:10.1146/annurev.food.080708.100754 · Cited by 1,637
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Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
Kalt, W., Cassidy, A., Howard, L. R., Krikorian, R., Stull, A. J., Tremblay, F., & Zamora-Ros, R. (2020) · Advances in Nutrition · doi:10.1093/advances/nmz065 · Cited by 659
Self-citationBlueberry supplementation improves memory in older adults
Krikorian, R., Shidler, M. D., Nash, T. A., Kalt, W., Vinqvist-Tymchuk, M. R., Shukitt-Hale, B., & Joseph, J. A. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9029332 · Cited by 582
Self-citationThe neuroprotective potential of flavonoids: a multiplicity of effects
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Cherry Antioxidants: From Farm to Table
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Self-citationUnraveling Anthocyanin Bioavailability for Human Health
Lila, M. A., Burton-Freeman, B., Grace, M., & Kalt, W. (2016) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-041715-033346 · Cited by 309
Self-citationMediterranean diet nutrients to turn the tide against insulin resistance and related diseases
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Metadata
- Authors
- Kalt, W., Blumberg, J. B., McDonald, J. E., Vinqvist-Tymchuk, M. R., Fillmore, S. A. E., Graf, B. A., O’Leary, J. M., & Milbury, P. E.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-02
- Volume
- 56
- Issue
- 3
- Pages
- 705-712
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W1973621432
- Cited by
- 336
- References
- 2
- FWCI
- 9.66
- Type
- journal article
- Language
- en
- Open access
- closed
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