The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Remarkable Increase in Nuclease Resistance of Plasmid DNA through Supramolecular Assembly with Poly(ethylene glycol)–Poly(l-lysine) Block Copolymer
Abstract
Supramolecular associates of DNA with Poly(ethylene glycol)-poly(L-lysine) block copolymers (PEG-PLL) were prepared in aqueous milieu, and the water solubility under charge-neutralized (stoichiometric) conditions was maintained. Associates thus prepared achieved remarkable resistance against nuclease attack, probably due to the formation of PEG palisade surrounding the ion-complexed core of the DNA with the PLL segment of the block copolymer. Further, to estimate the stability of the associate, the rate of interexchange reaction of DNA in the associate with poly(vinyl sulfonate) was evaluated from a method using a metachromasy of toluidine blue dye. Of interest, the nuclease resistance of DNA in PEG-PLL/DNA associate had an inverse correlation with the rate of interexchange reaction and, thus, progressively increased with an increase in the molecular weight of PLL segment in the block copolymer, indicating the substantial importance of block copolymer design for DNA stabilization.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Mechanism of oligonucleotide release from cationic liposomes.
Zelphati, O., & Szoka, F. C. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.21.11493 · Cited by 634
Cited by
Block copolymer micelles for drug delivery: design, characterization and biological significance
Kataoka, K., Harada, A., & Nagasaki, Y. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00124-1 · Cited by 3,506
Self-citationMicellar Nanocarriers: Pharmaceutical Perspectives
Torchilin, V. P. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9132-0 · Cited by 1,910
Nano-engineering block copolymer aggregates for drug delivery
Allen, C., Maysinger, D., & Eisenberg, A. (1999) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/s0927-7765(99)00058-2 · Cited by 1,358
Block copolymer micelles in nanomedicine applications
Cabral, H., Miyata, K., Osada, K., & Kataoka, K. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00199 · Cited by 1,309
Self-citationPolyethylene glycol (PEG): A versatile polymer for pharmaceutical applications
D’souza, A. A., & Shegokar, R. (2016) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2016.1182485 · Cited by 1,282
Polymeric micelles—A new generation of colloidal drug carriers
Jones, M.-C., & Leroux, J.-C. (1999) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(99)00039-9 · Cited by 1,256
Polymeric micelles as drug delivery vehicles
Ahmad, Z., Shah, A., Siddiq, M., & Kraatz, H.-B. (2014) · RSC Adv. · doi:10.1039/c3ra47370h · Cited by 610
Passive and Active Drug Targeting: Drug Delivery to Tumors as an Example
Torchilin, V. P. (2010) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-00477-3_1 · Cited by 573
PEG-based micelles as carriers of contrast agents for different imaging modalities
Torchilin, V. P. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00019-4 · Cited by 470
Miyata, K., Nishiyama, N., & Kataoka, K. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15258k · Cited by 451
Self-citationComplex coacervate‐based materials for biomedicine
Blocher, W. C., & Perry, S. L. (2017) · WIREs Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1442 · Cited by 312
Hamley, I. W. (2014) · Biomacromolecules · doi:10.1021/bm500246w · Cited by 300
Regulatable gene expression systems for gene therapy applications: progress and future challenges
Goverdhana, S., Puntel, M., Xiong, W., Zirger, J. M., Barcia, C., Curtin, J. F., Soffer, E. B., Mondkar, S., King, G. D., Hu, J., et al. (2005) · Molecular Therapy · doi:10.1016/j.ymthe.2005.03.022 · Cited by 283
Osada, K., Christie, R. J., & Kataoka, K. (2009) · Journal of The Royal Society Interface · doi:10.1098/rsif.2008.0547.focus · Cited by 218
Self-citation
Metadata
- Authors
- Katayose, S., & Kataoka, K.
- Venue
- Journal of Pharmaceutical Sciences
- Publisher
- American Geophysical Union (AGU)
- Published
- 1998-02
- Volume
- 87
- Issue
- 2
- Pages
- 160-163
- ISSN
- 0022-3549 (ISSN-L)
- OpenAlex
- W2064580002
- Cited by
- 238
- References
- 1
- FWCI
- 3.04
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
