The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Fabrication of Gradient Hydrogels Using a Microfluidics/Photopolymerization Process
Abstract
A method of fabricating photo-cross-linked hydrogels with gradients of immobilized molecules and crosslinking densities is introduced. Two macromer/initiator solutions are injected into a unique poly(dimethylsiloxane) channel system that produces a prepolymer gradient that is subsequently polymerized into a water-swollen hydrogel with ultraviolet light exposure. The gradient is controlled by the injection flow rate (optimized to 0.3 microL/min per inlet to produce a linear gradient). The technique is investigated both through fabrication of adhesive ligand gradients that modulate spatial distribution of attached endothelial cells and gradients of cross-linking densities that led to unique hydrogel architectures and spatially dependent swelling.
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Cites
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Self-citationPlatelet adhesion and activation on a shielded plasma gradient prepared on polyethylene
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Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology
Peppas, N. A., Hilt, J. Z., Khademhosseini, A., & Langer, R. (2006) · Advanced Materials · doi:10.1002/adma.200501612 · Cited by 4,109
Self-citationHydrogels in regenerative medicine
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Self-citationPolymeric Scaffolds in Tissue Engineering Application: A Review
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Microengineered hydrogels for tissue engineering
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Metadata
- Authors
- Burdick, J. A., Khademhosseini, A., & Langer, R.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-05-28
- Volume
- 20
- Issue
- 13
- Pages
- 5153-5156
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2013827506
- Cited by
- 374
- References
- 8
- FWCI
- 8.12
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
