The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Synthesis, Characterization, and Hydrolytic Degradation of PLA/PEO/PLA Triblock Copolymers with Short Poly(l-lactic acid) Chains
Abstract
PLA/PEO/PLA triblock copolymers bearing short poly( l -lactic acid) blocks, with the number average degree of polymerization of each PLA block PLA = 2, 4, 8, and 12, were synthesized by ring opening polymerization of l -lactide initiated by poly(ethylene glycol) in the presence of CaH 2 . The length of PEO blocks was varied by using parent PEG of different number average degrees of polymerization PEG = 14, 26, and 49, respectively, according to SEC and NMR. SEC and 1 H and 13 C NMR showed the resulting triblock copolymers did not contain any detectable PLA homopolymer as side product. The use of DMSO- d 6 as solvent for NMR analyses, instead of CDCl 3, greatly enhanced the resolution and permitted the distinction of the signals due to the last two constitutive units located at both ends of each PLA block. Data obtained by FTIR spectroscopy and X-ray diffractometry suggested that PEO and PLA blocks were phase separated even for copolymers with very short PLA blocks. Optical microscopy and DSC showed that an increase in the length of PLA blocks led to a decrease in the crystallinity of PEO blocks up to disappearance. Hydrolysis was carried out in DMSO/D 2 O in the presence of trifluoroacetic acid and monitored by NMR. Data suggested that intrachain and PEO/PLA connecting ester bonds were cleaved at comparable rates in the selected homogeneous medium.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Li, S. M., Garreau, H., & Vert, M. (1990) · Journal of Materials Science: Materials in Medicine · doi:10.1007/bf00700871 · Cited by 733
Self-citationBiodegradable PEO/PLA block copolymers
Cohn, D., & Younes, H. (1988) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820221104 · Cited by 241
Phase separation in poly(ethylene glycol)/poly(lactic acid) blends
Younes, H., & Cohn, D. (1988) · European Polymer Journal · doi:10.1016/0014-3057(88)90013-4 · Cited by 212
Jedliński, Z., Wałach, W., Kurcok, P., & Adamus, G. (1991) · Die Makromolekulare Chemie · doi:10.1002/macp.1991.021920914 · Cited by 116
Morphological study of biodegradable PEO/PLA block copolymers
Younes, H., & Cohn, D. (1987) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820211103 · Cited by 82
Cited by
Polymeric systems for controlled drug release
Uhrich, K. E., Cannizzaro, S. M., Langer, R. S., & Shakesheff, K. M. (1999) · Chemical Reviews · doi:10.1021/cr940351u · Cited by 2,633
25th Anniversary Article: Engineering Hydrogels for Biofabrication
Malda, J., Visser, J., Melchels, F. P., Jüngst, T., Hennink, W. E., Dhert, W. J. A., Groll, J., & Hutmacher, D. W. (2013) · Advanced Materials · doi:10.1002/adma.201302042 · Cited by 1,901
Biodegradable Polymers-A Review on Recent Trends and Emerging Perspectives
Luckachan, G. E., & Pillai, C. K. S. (2011) · Journal of Polymers and the Environment · doi:10.1007/s10924-011-0317-1 · Cited by 767
Biocompatible Initiators for Lactide Polymerization
Platel, R., Hodgson, L., & Williams, C. (2008) · Polymer Reviews · doi:10.1080/15583720701834166 · Cited by 706
Plasticizing polylactide—the effect of different plasticizers on the mechanical properties
Jacobsen, S., & Fritz, H. G. (1999) · Polymer Engineering & Science · doi:10.1002/pen.11517 · Cited by 540
Designing biodegradable multiblock PCL/PLA thermoplastic elastomers
Cohn, D., & Hotovely Salomon, A. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.07.052 · Cited by 355
Functionalized synthetic biodegradable polymer scaffolds for tissue engineering.
Liu, X., Holzwarth, J. M., & Ma, P. X. (2012) · Macromolecular Bioscience · doi:10.1002/mabi.201100466 · Cited by 290
Ljungberg, N., & Wesslén, B. (2003) · Polymer · doi:10.1016/j.polymer.2003.09.055 · Cited by 278
Castillo, R. V., & Müller, A. J. (2009) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2009.03.002 · Cited by 253
Yeh, J., Tsou, C., Huang, C., Chen, K., Wu, C., & Chai, W. (2010) · Journal of Applied Polymer Science · doi:10.1002/app.30907 · Cited by 199
Breitenbach, A., & Kissel, T. (1998) · Polymer · doi:10.1016/s0032-3861(97)10077-5 · Cited by 117
Maglio, G., Migliozzi, A., & Palumbo, R. (2003) · Polymer · doi:10.1016/s0032-3861(02)00764-4 · Cited by 111
Ljungberg, N., Colombini, D., & Wesslén, B. (2005) · Journal of Applied Polymer Science · doi:10.1002/app.21163 · Cited by 73
Genovese, L., Soccio, M., Lotti, N., Gazzano, M., Siracusa, V., Salatelli, E., Balestra, F., & Munari, A. (2017) · European Polymer Journal · doi:10.1016/j.eurpolymj.2017.08.001 · Cited by 56
In vitro ageing and degradation of PEG-PLA diblock copolymer-based nanoparticles
Stefani, M., Coudane, J., & Vert, M. (2006) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2006.05.009 · Cited by 52
Self-citationHuang, C., Tsai, S., & Chen, C. (2006) · Journal of Polymer Science Part B: Polymer Physics · doi:10.1002/polb.20890 · Cited by 45
In vitro degradation behavior of biodegradable 4-star micelles
Salaam, L. E., Dean, D., & Bray, T. L. (2006) · Polymer · doi:10.1016/j.polymer.2005.10.134 · Cited by 40
Ponsart, S., Coudane, J., McGrath, J., & Vert, M. (2002) · Journal of Bioactive and Compatible Polymers · doi:10.1177/088391102030911 · Cited by 24
Self-citationLeroy, A., Pinese, C., Bony, C., Garric, X., Noël, D., Nottelet, B., & Coudane, J. (2013) · Materials Science and Engineering C · doi:10.1016/j.msec.2013.06.001 · Cited by 22
Palacios, J. K., Mugica, A., Zubitur, M., & Müller, A. J. (2018) · Crystallization in Multiphase Polymer Systems · doi:10.1016/b978-0-12-809453-2.00006-2 · Cited by 18
Thermo‐Responsive Hydrogels Based on Branched Poly(L‐lactide)‐poly(ethylene glycol) Copolymers
Velthoen, I. W., Tijsma, E. J., Dijkstra, P. J., & Feijen, J. (2008) · Macromolecular Symposia · doi:10.1002/masy.200851202 · Cited by 13
Metadata
- Authors
- Rashkov, I., Manolova, N., Li, S. M., Espartero, J. L., & Vert, M.
- Venue
- Macromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 1996-01-01
- Volume
- 29
- Issue
- 1
- Pages
- 50-56
- ISSN
- 0024-9297 (ISSN-L)
- 1520-5835
- OpenAlex
- W2030960478
- Cited by
- 371
- References
- 5
- FWCI
- 9.81
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
