Structure-property relationships in the case of the degradation of massive aliphatic poly-(?-hydroxy acids) in aqueous media: Part 1: Poly(dl-lactic acid)
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The rate of water diffusion depends on the hydrophobicity of the polymer and its shape or surface area while the intrinsic degradation kinetics is affected by the pH and temperature of the medium as well as the molecular weight and microstructures of the polymer.
“The rate of water diffusion depends on the hydrophobicity of the polymer and its shape or surface area while the intrinsic degradation kinetics is affected by the pH 421 and temperature of the medium 422 as well as the molecular weight 423 and microstructures of the polymer.424”
From Catalysis as an Enabling Science for Sustainable Polymers (2018) · cites this paper as [423]
Cites
Biodegradable polymers for use in surgery—polyglycolic/poly(actic acid) homo- and copolymers: 1
Gilding, D. K., & Reed, A. M. (1979) · Polymer · doi:10.1016/0032-3861(79)90009-0 · Cited by 1,345 · see citing works
Fischer, E. W., Sterzel, H. J., & Wegner, G. (1973) · Aktuelle Probleme der Polymer-Physik · doi:10.1007/978-3-642-47050-9_24 · Cited by 682 · see citing works
Reed, A. M., & Gilding, D. K. (1981) · Polymer · doi:10.1016/0032-3861(81)90168-3 · Cited by 611 · see citing works
Holland, S. J., Tighe, B. J., & Gould, P. L. (1986) · Journal of Controlled Release · doi:10.1016/0168-3659(86)90001-5 · Cited by 480 · see citing works
General crystallization behaviour of poly(l-lactic acid)
Kalb, B., & Pennings, A. J. (1980) · Polymer · doi:10.1016/0032-3861(80)90315-8 · Cited by 422 · see citing works
Fundamental aspects of biocompatibility
Williams, D. F. (1981) · CRC Press eBooks · Cited by 300 · see citing works
Brady, J. M., Cutright, D. E., Miller, R. A., Battistone, G. C., & Hunsuck, E. E. (1973) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820070204 · Cited by 280 · see citing works
Polylactide. II. Viscosity–molecular weight relationships and unperturbed chain dimensions
Schindler, A., & Harper, D. (1979) · Journal of Polymer Science Polymer Chemistry Edition · doi:10.1002/pol.1979.170170831 · Cited by 279 · see citing works
Bioabsorption of polylactides with different molecular properties
Nakamura, T., Hitomï, S., Watanabe, S., Shimizu, Y., Jamshidi, K., Hyon, S. H., & Ikada, Y. (1989) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820231003 · Cited by 240 · see citing works
Configurational structures of lactic acid stereocopolymers as determined by 13C{1H} n.m.r.
Chabot, F., Vert, M., Chapelle, S., & Granger, P. (1983) · Polymer · doi:10.1016/0032-3861(83)90080-0 · Cited by 234 · see citing works
Self-citationBiodegradation of and tissue reaction to 50:50 poly(DL‐lactide‐co‐glycolide) microcapsules
Visscher, G. E., Robison, R. L., Maulding, H. V., et al. (1985) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820190315 · Cited by 222 · see citing works
Degradation rates of polymers and copolymers of polylactic and polyglycolic acids
Cutright, D. E., Perez, B., Beasley, J. D., et al. (1974) · Oral Surgery Oral Medicine Oral Pathology · doi:10.1016/0030-4220(74)90171-6 · Cited by 213 · see citing works
Stereoregular bioresorbable polyesters for orthopaedic surgery
Vert, M., Chabot, F., Leray, J., & Christel, P. (1981) · Die Makromolekulare Chemie · doi:10.1002/macp.1981.020051981103 · Cited by 206 · see citing works
Self-citationPreparation and in vitro degradation properties of polylactide microcapsules.
Makino, K., Arakawa, M., & Kondo, T. (1985) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.33.1195 · Cited by 200 · see citing works
Kinetik und Mechanismus der ringöffnenden Polymerisation von L(—)‐Lactid
Dittrich, V. W., & Schulz, R. C. (1971) · Die Angewandte Makromolekulare Chemie · doi:10.1002/apmc.1971.050150109 · Cited by 149 · see citing works
The enzymatic degradation of polymers in vitro
Smith, R., Oliver, C., & Williams, D. F. (1987) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820210805 · Cited by 139 · see citing works
Makino, K., Ohshima, H., & Kondo, T. (1986) · Journal of Microencapsulation · doi:10.3109/02652048609031574 · Cited by 138 · see citing works
The acceleration of degradation-controlled drug delivery from polyester microspheres
Cha, Y., & Pitt, C. G. (1989) · Journal of Controlled Release · doi:10.1016/0168-3659(89)90047-3 · Cited by 102 · see citing works
(2018) · CRC Press eBooks · doi:10.1201/9781351074223 · Cited by 36 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The design of scaffolds for use in tissue engineering. Part I. Traditional factors
Yang, S., Leong, K.-F., Du, Z., & Chua, C.-K. (2001) · Tissue Engineering · doi:10.1089/107632701753337645 · Cited by 2,234 · see citing works
Mechanisms of polymer degradation and erosion
Göpferich, A. (1996) · Biomaterials · doi:10.1016/0142-9612(96)85755-3 · Cited by 1,781 · see citing works
Properties of lactic acid based polymers and their correlation with composition
Södergård, A., & Stolt, M. (2002) · Progress in Polymer Science · doi:10.1016/s0079-6700(02)00012-6 · Cited by 1,461 · see citing works
Catalysis as an Enabling Science for Sustainable Polymers
Zhang, X., Fevre, M., Jones, G. O., & Waymouth, R. M. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00329 · Cited by 936 · see citing works
Hydrolytic degradation of devices based on poly(DL-lactic acid) size-dependence
Grizzi, I., Garreau, H., Li, S., & Vert, M. (1995) · Biomaterials · doi:10.1016/0142-9612(95)93258-f · Cited by 895 · see citing works
Self-citationIn vitro and in vivo degradation of porous poly(dl-lactic-co-glycolic acid) foams
Lu, L., Peter, S. J., D. Lyman, M., Lai, H.-L., Leite, S. M., Tamada, J. A., Uyama, S., Vacanti, J. P., Langer, R., & Mikos, A. G. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00047-8 · Cited by 668 · see citing works
Degradation of poly(lactic-co-glycolic acid) microspheres: Effect of copolymer composition
Park, T. G. (1995) · Biomaterials · doi:10.1016/0142-9612(95)93575-x · Cited by 642 · see citing works
Alexis, F. (2005) · Polymer International · doi:10.1002/pi.1697 · Cited by 443 · see citing works
Lam, C. X. F., Savalani, M. M., Teoh, S.-H., & Hutmacher, D. W. (2008) · Biomedical Materials · doi:10.1088/1748-6041/3/3/034108 · Cited by 444 · see citing works
Melt–solid polycondensation of lactic acid and its biodegradability
Maharana, T., Mohanty, B., & Negi, Y. S. (2009) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2008.10.001 · Cited by 368 · see citing works
Degradation of poly (D,L-lactic acid) microspheres: Effect of molecular weight
Park, T. G. (1994) · Journal of Controlled Release · doi:10.1016/0168-3659(94)90263-1 · Cited by 359 · see citing works
Tsuji, H., & Ikada, Y. (2000) · Polymer Degradation and Stability · doi:10.1016/s0141-3910(99)00111-1 · Cited by 329 · see citing works
Wu, X. S., & Wang, N. (2001) · Journal of Biomaterials Science, Polymer Edition · doi:10.1163/156856201744425 · Cited by 317 · see citing works
Bioabsorbable implant material review
Maurus, P. B., & Kaeding, C. C. (2004) · Operative Techniques in Sports Medicine · doi:10.1053/j.otsm.2004.07.015 · Cited by 280 · see citing works
Biodegradation of polylactide in aerobic and anaerobic thermophilic conditions
Itävaara, M., Karjomaa, S., & Selin, J.-F. (2002) · Chemosphere · doi:10.1016/s0045-6535(01)00163-1 · Cited by 269 · see citing works
Huang, M.-H., Li, S., & Vert, M. (2004) · Polymer · doi:10.1016/j.polymer.2004.10.054 · Cited by 222 · see citing works
Self-citationTsuji, H., & Miyauchi, S. (2001) · Polymer Degradation and Stability · doi:10.1016/s0141-3910(00)00191-9 · Cited by 204 · see citing works
Controlled release from bioerodible polymers: Effect of drug type and polymer composition
Frank, A., Rath, S. K., & Venkatraman, S. S. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.10.019 · Cited by 201 · see citing works
Degradation of poly-L-lactide. Part 2: increased temperature accelerated degradation
Weir, N. A., Buchanan, F. J., Orr, J. F., Farrar, D. F., & Dickson, G. R. (2004) · Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine · doi:10.1243/0954411041932809 · Cited by 171 · see citing works
Gleadall, A., Pan, J., Kruft, M.-A., & Kellomäki, M. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.12.039 · Cited by 165 · see citing works
Hydrolytic degradation of oligo(lactic acid): a kinetic and mechanistic study
van Nostrum, C. F., Veldhuis, T. F. J., Bos, G. W., & Hennink, W. E. (2004) · Polymer · doi:10.1016/j.polymer.2004.08.001 · Cited by 150 · see citing works
Schliecker, G., Schmidt, C., Fuchs, S., Wombacher, R., & Kissel, T. (2003) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(03)00379-x · Cited by 146 · see citing works
Ye, W. P., Du, F. S., Jin, W. H., Yang, J. Y., & Xu, Y. (1997) · Reactive and Functional Polymers · doi:10.1016/s1381-5148(96)00081-8 · Cited by 142 · see citing works
Grayson, A. C. R., Cima, M. J., & Langer, R. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.06.033 · Cited by 124 · see citing works
Elevated temperature degradation of a 50:50 copolymer of PLA-PGA
Agrawal, C. M., Huang, D., Schmitz, J. P., & Athanasiou, K. A. (1997) · Tissue Engineering · doi:10.1089/ten.1997.3.345 · Cited by 120 · see citing works
Degradable shape-memory polymer networks from oligo[(l-lactide)-ran-glycolide]dimethacrylates
Choi, N.-Y., & Lendlein, A. (2007) · Soft Matter · doi:10.1039/b702515g · Cited by 110 · see citing works
Degradation characteristics of poly(ϵ‐caprolactone)‐based copolymers and blends
Huang, M., Li, S., Hutmacher, D. W., Coudane, J., & Vert, M. (2006) · Journal of Applied Polymer Science · doi:10.1002/app.24196 · Cited by 104 · see citing works
Self-citationPolylactic acid (PLA)-based multifunctional and biodegradable nanocomposites and their applications
Islam, M. S., Elahee, G. M. F., Fang, Y., Yu, X. (., Advincula, R. C., & Cao, C. (. (2025) · Composites Part B Engineering · doi:10.1016/j.compositesb.2025.112842 · Cited by 86 · see citing works
Gleadall, A., Pan, J., & Atkinson, H. (2012) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2012.06.023 · Cited by 67 · see citing works
Fungal degradation of poly(butylene adipate-co-terephthalate) in soil, and in compost
Saadi, Z., Cesar, G., Bewa, H., & Benguigui, L. (2013) · Journal of Polymers and the Environment · doi:10.1007/s10924-013-0582-2 · Cited by 66 · see citing works
Accelerated in vitro degradation properties of polylactic acid/phosphate glass fibre composites
Felfel, R. M., Hossain, K. M. Z., Parsons, A. J., Rudd, C. D., & Ahmed, I. (2015) · Journal of Materials Science · doi:10.1007/s10853-015-8946-8 · Cited by 61 · see citing works
Long-term delivery of all-trans-retinoic acid using biodegradable PLLA/PEG-PLLA blended microspheres
Choi, Y., Kim, S. Y., Kim, S. H., Lee, K.-S., Kim, C., & Byun, Y. (2001) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(00)00676-1 · Cited by 54 · see citing works
In vitro ageing and degradation of PEG-PLA diblock copolymer-based nanoparticles
Stefani, M., Coudane, J., & Vert, M. (2006) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2006.05.009 · Cited by 52 · see citing works
Self-citationDong, J., Liao, L., Ma, Y., Shi, L., Wang, G., Fan, Z., Li, S., & Lu, Z. (2014) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2014.03.004 · Cited by 35 · see citing works
Self-citationMayer, J. B., Patil, S. M., Shin, S.-H., Yoo, J., & Won, Y.-Y. (2025) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c00419 · Cited by 38 · see citing works
Leroy, A., Pinese, C., Bony, C., Garric, X., Noël, D., Nottelet, B., & Coudane, J. (2013) · Materials Science and Engineering C · doi:10.1016/j.msec.2013.06.001 · Cited by 22 · see citing works
- Authors
- Li, S. M., Garreau, H., & Vert, M.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- ORCID
- Vert, M.
- Venue
- Journal of Materials Science: Materials in Medicine
- Published
- 1990-10
- Volume
- 1
- Issue
- 3
- Pages
- 123-130
- ISSN
- 0957-4530 (ISSN-L)
- 1573-4838
- OpenAlex
- W2049805949
- Cited by
- 733
- References
- 19
- Citations by year
- 2026: 6 · 2025: 4 · 2024: 6 · 2023: 10 · 2022: 9 · 2021: 14 · 2020: 15 · 2019: 25 · 2018: 9 · 2017: 20 · 2016: 16 · 2015: 24 · 2014: 29 · 2013: 27 · 2012: 33
- FWCI
- 10.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Materials Science Materials in Medicine (publishedVersion)
- HAL (submittedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Health Sciences › Medicine › Surgery › Surgical Sutures and Adhesives
- Physical Sciences › Materials Science › Biomaterials › Magnesium Alloys: Properties and Applications
- Keywords
- poly(α-hydroxy acids), poly(L-lactic acid), hydrolytic degradation, structure-property relationships, bioresorbable polymers, degradation mechanism, surface degradation, autocatalytic mechanism, ester bond cleavage, bimodal size distribution, amorphous polymers
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review