The DOI matches its Crossref record.
Generation of Synthetic Elastin-Mimetic Small Diameter Fibers and Fiber Networks
Abstract
Elastin-mimetic peptide polymers have been synthesized, and the morphological properties of fabricated small diameter fibers and nonwoven fabrics have been characterized. An 81 kDa recombinant protein based upon the repeating elastomeric peptide sequence of elastin (Val-Pro-Gly-Val-Gly) 4 (Val-Pro-Gly-Lys-Gly) was obtained through bacterial expression of an oligomerized gene coding for tandem repeats of the monomer. The protein was processed into fibers by an electrospinning technique and morphology defined by SEM and TEM. The choice of processing parameters influenced both fiber diameter and morphology with diameters varying between 200 and 3000 nm and three morphological patterns noted: beaded fibers, thin filaments, and broad ribbonlike structures. Detailed image analysis of nonwoven textile fabrics produced from elastin-mimetic fibers revealed that the distribution of single fiber orientation was isotropic with an associated unimodal distribution of protein fiber diameter. In a dry state, the ultimate tensile strength of nonwoven fabrics generated from elastin-mimetic peptides was 35 MPa with a material modulus of 1.8 GPa.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Altman, G. H., Diaz, F., Jakuba, C., Calabro, T., Horan, R. L., Chen, J., Lu, H., Richmond, J., & Kaplan, D. L. (2003) · Biomaterials · doi:10.1016/s0142-9612(02)00353-8 · Cited by 3,458
Designing materials for biology and medicine
Langer, R., & Tirrell, D. A. (2004) · Nature · doi:10.1038/nature02388 · Cited by 3,198
Kenawy, E.-R., Bowlin, G. L., Mansfield, K., Layman, J., Simpson, D. G., Sanders, E. H., & Wnek, G. E. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00041-x · Cited by 1,311
Biomimetic materials for tissue engineering
Ma, P. X. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.08.041 · Cited by 1,310
Scaffolds for tissue fabrication
Ma, P. X. (2004) · Materials Today · doi:10.1016/s1369-7021(04)00233-0 · Cited by 1,077
Biodegradable electrospun fibers for drug delivery
Zeng, J., Xu, X., Chen, X., Liang, Q., Bian, X., Yang, L., & Jing, X. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00372-9 · Cited by 832
Electrospinning and electrically forced jets. II. Applications
Hohman, M. M., Shin, M., Rutledge, G., & Brenner, M. P. (2001) · Physics of Fluids · doi:10.1063/1.1384013 · Cited by 698
Recent development of polymer nanofibers for biomedical and biotechnological applications
Zhang, Y., Lim, C. T., Ramakrishna, S., & Huang, Z.-M. (2005) · Journal of Materials Science: Materials in Medicine · doi:10.1007/s10856-005-4428-x · Cited by 649
Human bone marrow stromal cell responses on electrospun silk fibroin mats
Jin, H.-J., Chen, J., Karageorgiou, V., Altman, G. H., & Kaplan, D. L. (2004) · Biomaterials · doi:10.1016/s0142-9612(03)00609-4 · Cited by 631
Son, W. K., Youk, J. H., Lee, T. S., & Park, W. H. (2004) · Polymer · doi:10.1016/j.polymer.2004.03.006 · Cited by 616
Sell, S. A., Wolfe, P. S., Garg, K., McCool, J. M., Rodriguez, I. A., & Bowlin, G. L. (2010) · Polymers · doi:10.3390/polym2040522 · Cited by 578
Lu, X., Wang, C., Favier, F., & Pinna, N. (2017) · Advanced Energy Materials · doi:10.1002/aenm.201601301 · Cited by 429
Generation of electrospun fibers of nylon 6 and nylon 6-montmorillonite nanocomposite
Fong, H. (2002) · Polymer · doi:10.1016/s0032-3861(01)00665-6 · Cited by 396
Silk scaffolds in bone tissue engineering: An overview
Bhattacharjee, P., Kundu, B., Naskar, D., Kim, H.-W., Maiti, T. K., Bhattacharya, D., & Kundu, S. C. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.09.027 · Cited by 318
Zhang, Y., Avery, R. K., Vallmajo‐Martin, Q., Assmann, A., Vegh, A., Memic, A., Olsen, B. D., Annabi, N., & Khademhosseini, A. (2015) · Advanced Functional Materials · doi:10.1002/adfm.201501489 · Cited by 270
Lee, J., Tae, G., Kim, Y. H., Park, I. S., Kim, S.-H., & Kim, S. H. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2007.12.029 · Cited by 200
Metadata
- Authors
- Huang, L., McMillan, R. A., Apkarian, R. P., Pourdeyhimi, B., Conticello, V. P., & Chaikof, E. L.
- Venue
- Macromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2000-03-24
- Volume
- 33
- Issue
- 8
- Pages
- 2989-2997
- ISSN
- 0024-9297 (ISSN-L)
- 1520-5835
- OpenAlex
- W1964284889
- Cited by
- 352
- References
- 0
- FWCI
- 9.06
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
