The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Compact Zwitterion-Coated Iron Oxide Nanoparticles for Biological Applications
Open accessAbstract
The potential of superparamagnetic iron oxide nanoparticles (SPIONs) in various biomedical applications, including magnetic resonance imaging (MRI), sensing, and drug delivery, requires that their surface be derivatized to be hydrophilic and biocompatible. We report here the design and synthesis of a compact and water-soluble zwitterionic dopamine sulfonate (ZDS) ligand with strong binding affinity to SPIONs. After ligand exchange, the ZDS-coated SPIONs exhibit small hydrodynamic diameters, and stability with respect to time, pH, and salinity. Furthermore, small ZDS coated SPIONs were found to have a reduced nonspecific affinity (compared to negatively charged SPIONs) toward serum proteins; streptavidin/dye functionalized SPIONs were bioactive and thus specifically targeted biotin receptors.
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Cites
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Self-citationMultifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications
Gao, J., Gu, H., & Xu, B. (2009) · Accounts of Chemical Research · doi:10.1021/ar9000026 · Cited by 1,907
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Cited by
Nanomaterials for In Vivo Imaging
Smith, B. R., & Gambhir, S. S. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00073 · Cited by 1,075
In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles
Arami, H., Khandhar, A., Liggitt, D., & Krishnan, K. M. (2015) · Chemical Society Reviews · doi:10.1039/c5cs00541h · Cited by 830
Imaging macrophages with nanoparticles
Weissleder, R., Nahrendorf, M., & Pittet, M. J. (2014) · Nature Materials · doi:10.1038/nmat3780 · Cited by 809
Organic Phase Syntheses of Magnetic Nanoparticles and Their Applications
Wu, L., Mendoza-Garcia, A., Li, Q., & Sun, S. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00687 · Cited by 601
Surface modification of magnetic iron oxide nanoparticles
Zhu, N., Ji, H., Yu, P., Niu, J., Farooq, M. U., Akram, M. W., Udego, I. O., Li, H., & Niu, X. (2018) · Nanomaterials · doi:10.3390/nano8100810 · Cited by 569
Metadata
- Authors
- Wei, H., Insin, N., Lee, J., Han, H.-S., Cordero, J. M., Liu, W., & Bawendi, M. G.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-12-20
- Volume
- 12
- Issue
- 1
- Pages
- 22-25
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1549857425
- Cited by
- 245
- References
- 4
- FWCI
- 7.84
- Type
- journal article
- Language
- en
- Open access
- green
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