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High Contrast in Vitro and in Vivo Photoluminescence Bioimaging Using Near Infrared to Near Infrared Up-Conversion in Tm3+ and Yb3+ Doped Fluoride Nanophosphors
Open accessAbstract
A new approach for photoluminescence imaging in vitro and in vivo has been shown utilizing near infrared to near infrared (NIR-to-NIR) up-conversion in nanophosphors. This NIR-to-NIR up-conversion process provides deeper light penetration into biological specimen and results in high contrast optical imaging due to absence of an autofluorescence background and decreased light scattering. Aqueous dispersible fluoride (NaYF4) nanocrystals (20-30 nm size) co-doped with the rare earth ions, Tm(3+) and Yb(3+), were synthesized and characterized by TEM, XRD, and photoluminescence (PL) spectroscopy. In vitro cellular uptake was shown by the PL microscopy visualizing the characteristic emission of Tm(3+) at approximately 800 nm excited with 975 nm. No apparent cytotoxicity was observed. Subsequent animal imaging studies were performed using Balb-c mice injected intravenously with up-converting nanophosphors, demonstrating the high contrast PL imaging in vivo.
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Cites
A clearer vision for in vivo imaging
Weissleder, R. (2001) · Nature Biotechnology · doi:10.1038/86684 · Cited by 3,839
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Self-citationAdvanced Fluorescence Imaging Technology in the Near-Infrared-II Window for Biomedical Applications
Li, C., Chen, G., Zhang, Y., Wu, F., & Wang, Q. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c07022 · Cited by 1,037
Nanomaterials: Applications in Cancer Imaging and Therapy
Barreto, J. A., O’Malley, W., Kubeil, M., Graham, B., Stephan, H., & Spiccia, L. (2011) · Advanced Materials · doi:10.1002/adma.201100140 · Cited by 907
Hemmer, E., Benayas, A., Légaré, F., & Vetrone, F. (2016) · Nanoscale Horizons · doi:10.1039/c5nh00073d · Cited by 731
Chen, G., Shen, J., Ohulchanskyy, T. Y., Patel, N. J., Kutikov, A., Li, Z., Song, J., Pandey, R. K., Ågren, H., Prasad, P. N., et al. (2012) · ACS Nano · doi:10.1021/nn302972r · Cited by 720
Self-citationRare earth fluoride nano-/microcrystals: synthesis, surface modification and application
Li, C., & Lin, J. (2010) · Journal of Materials Chemistry · doi:10.1039/c0jm00031k · Cited by 675
Wang, C., Cheng, L., & Liu, Z. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2010.09.069 · Cited by 666
Chen, G., Ohulchanskyy, T. Y., Kumar, R., Ågren, H., & Prasad, P. N. (2010) · ACS Nano · doi:10.1021/nn100457j · Cited by 632
Self-citationPark, Y. I., Kim, J. H., Lee, K. T., Jeon, K., Na, H. B., Yu, J. H., Kim, H. M., Lee, N., Choi, S. H., Baik, S., et al. (2009) · Advanced Materials · doi:10.1002/adma.200901356 · Cited by 585
Xiao, Q., Zheng, X., Bu, W., Ge, W., Zhang, S., Chen, F., Xing, H., Ren, Q., Fan, W., Zhao, K., et al. (2013) · Journal of the American Chemical Society · doi:10.1021/ja404985w · Cited by 554
Xiong, L., Yang, T., Yang, Y., Xu, C., & Li, F. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.05.065 · Cited by 553
Kumar, R., Roy, I., Ohulchanskky, T. Y., Vathy, L. A., Bergey, E. J., Sajjad, M., & Prasad, P. N. (2010) · ACS Nano · doi:10.1021/nn901146y · Cited by 548
Self-citationZhou, J., Sun, Y., Du, X., Xiong, L., Hu, H., & Li, F. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.01.040 · Cited by 548
Multifunctional nanoprobes for upconversion fluorescence, MR and CT trimodal imaging
Xing, H., Bu, W., Zhang, S., Zheng, X., Li, M., Chen, F., He, Q., Zhou, L., Peng, W., Hua, Y., et al. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2011.10.039 · Cited by 408
Park, Y. I., Kim, H. M., Kim, J. H., Moon, K. C., Yoo, B., Lee, K. T., Lee, N., Choi, Y., Park, W., Ling, D., et al. (2012) · Advanced Materials · doi:10.1002/adma.201202433 · Cited by 395
Lanthanide-doped up-converting nanoparticles: Merits and challenges
Gnach, A., & Bednarkiewicz, A. (2012) · Nano Today · doi:10.1016/j.nantod.2012.10.006 · Cited by 393
Cheng, L., Yang, K., Li, Y., Zeng, X., Shao, M., Lee, S.-T., & Liu, Z. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2011.11.069 · Cited by 386
Liu, K., Liu, X., Zeng, Q., Zhang, Y., Tu, L., Liu, T., Kong, X., Wang, Y., Cao, F., Lambrechts, S. A. G., et al. (2012) · ACS Nano · doi:10.1021/nn300436b · Cited by 382
Subtissue Thermal Sensing Based on Neodymium-Doped LaF3Nanoparticles
Rocha, U., Jacinto da Silva, C., Ferreira Silva, W., Guedes, I., Benayas, A., Martínez Maestro, L., Acosta Elias, M., Bovero, E., van Veggel, F. C. J. M., García Solé, J. A., et al. (2013) · ACS Nano · doi:10.1021/nn304373q · Cited by 382
Upconverting luminescent nanomaterials: application to in vivo bioimaging
Hilderbrand, S. A., Shao, F., Salthouse, C., Mahmood, U., & Weissleder, R. (2009) · Chemical Communications · doi:10.1039/b905927j · Cited by 345
The biosafety of lanthanide upconversion nanomaterials
Sun, Y., Feng, W., Yang, P., Huang, C., & Li, F. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00175c · Cited by 309
Upconversion luminescence imaging of cells and small animals
Liu, Q., Feng, W., Yang, T., Yi, T., & Li, F. (2013) · Nature Protocols · doi:10.1038/nprot.2013.114 · Cited by 291
Design and development of fluorescent nanostructures for bioimaging
Chen, M., & Yin, M. (2014) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2013.11.001 · Cited by 289
Li, L.-L., Wu, P., Hwang, K., & Lu, Y. (2013) · Journal of the American Chemical Society · doi:10.1021/ja310432u · Cited by 280
Golovynskyi, S., Golovynska, I., Stepanova, L. I., Datsenko, O. I., Liu, L., Qu, J., & Ohulchanskyy, T. Y. (2018) · Journal of Biophotonics · doi:10.1002/jbio.201800141 · Cited by 209
Self-citation
Metadata
- Authors
- Nyk, M., Kumar, R., Ohulchanskyy, T. Y., Bergey, E. J., & Prasad, P. N.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-10-18
- Volume
- 8
- Issue
- 11
- Pages
- 3834-3838
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1994460217
- Cited by
- 905
- References
- 1
- FWCI
- 28.80
- Type
- journal article
- Language
- en
- Open access
- green
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