The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Nano/Microscale Motors: Biomedical Opportunities and Challenges
Abstract
Artificial nano/microscale machines hold great promise for diverse future biomedical applications. This Perspective summarizes recent advances in microscale motors, as exemplified by Hoyos and Mallouk in this issue of ACS Nano, and highlights the challenges and opportunities in translating this remarkable progress toward practical biomedical applications. Various areas of medicine, including targeted drug delivery, precision nanosurgery, biopsy, cell sorting, or diagnostic assays, would benefit from recent developments of efficient fuel-free and fuel-driven nano/microscale machines. Newly introduced ultrasound-driven propulsion mechanisms greatly enhance the prospects for these biomedical applications. With continuous innovation and attention to key challenges, we expect that man-made nano/microscale motors will have profound impact upon different medical areas.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Catalytic Nanomotors: Autonomous Movement of Striped Nanorods
Paxton, W. F., Kistler, K. C., Olmeda, C. C., Sen, A., St. Angelo, S. K., Cao, Y., Mallouk, T. E., Lammert, P. E., & Crespi, V. H. (2004) · Journal of the American Chemical Society · doi:10.1021/ja047697z · Cited by 2,128
Microrobots for Minimally Invasive Medicine
Nelson, B. J., Kaliakatsos, I. K., & Abbott, J. J. (2010) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-010510-103409 · Cited by 1,968
Controlled Propulsion of Artificial Magnetic Nanostructured Propellers
Ghosh, A., & Fischer, P. (2009) · Nano Letters · doi:10.1021/nl900186w · Cited by 1,296
Autonomous Motion of Metallic Microrods Propelled by Ultrasound
Wang, W., Castro, L. A., Hoyos, M., & Mallouk, T. E. (2012) · ACS Nano · doi:10.1021/nn301312z · Cited by 736
Catalytic Microtubular Jet Engines Self‐Propelled by Accumulated Gas Bubbles
Solovev, A. A., Mei, Y., Bermúdez Ureña, E., Huang, G., & Schmidt, O. G. (2009) · Small · doi:10.1002/smll.200900021 · Cited by 681
Mei, Y., Huang, G., Solovev, A. A., Ureña, E. B., Mönch, I., Ding, F., Reindl, T., Fu, R. K. Y., Chu, P. K., & Schmidt, O. G. (2008) · Advanced Materials · doi:10.1002/adma.200801589 · Cited by 658
Rolled-up nanotech on polymers: from basic perception to self-propelled catalytic microengines
Mei, Y., Solovev, A. A., Sanchez, S., & Schmidt, O. G. (2011) · Chemical Society Reviews · doi:10.1039/c0cs00078g · Cited by 650
Ultrasonic drug delivery – a general review
Pitt, W. G., Husseini, G. A., & Staples, B. J. (2004) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.1.1.37 · Cited by 621
Autonomous movement of platinum-loaded stomatocytes
Wilson, D. A., Nolte, R. J. M., & van Hest, J. C. M. (2012) · Nature Chemistry · doi:10.1038/nchem.1281 · Cited by 598
Synthetic self-propelled nanorotors
Fournier-Bidoz, S., Arsenault, A. C., Manners, I., & Ozin, G. A. (2005) · Chemical Communications · doi:10.1039/b414896g · Cited by 554
Gao, W., Sattayasamitsathit, S., Orozco, J., & Wang, J. (2011) · Journal of the American Chemical Society · doi:10.1021/ja203773g · Cited by 542
Self-citationCharacterizing the Swimming Properties of Artificial Bacterial Flagella
Zhang, L., Abbott, J. J., Dong, L., Peyer, K. E., Kratochvil, B. E., Zhang, H., Bergeles, C., & Nelson, B. J. (2009) · Nano Letters · doi:10.1021/nl901869j · Cited by 489
Schooling Behavior of Light‐Powered Autonomous Micromotors in Water
Ibele, M., Mallouk, T. E., & Sen, A. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200804704 · Cited by 471
Cargo‐Towing Fuel‐Free Magnetic Nanoswimmers for Targeted Drug Delivery
Gao, W., Kagan, D., Pak, O. S., Clawson, C., Campuzano, S., Chuluun‐Erdene, E., Shipton, E., Fullerton, E. E., Zhang, L., Lauga, E., et al. (2012) · Small · doi:10.1002/smll.201101909 · Cited by 451
Self-citationSolovev, A. A., Sanchez, S., Pumera, M., Mei, Y. F., & Schmidt, O. G. (2010) · Advanced Functional Materials · doi:10.1002/adfm.200902376 · Cited by 446
Can Man-Made Nanomachines Compete with Nature Biomotors?
Wang, J. (2009) · ACS Nano · doi:10.1021/nn800829k · Cited by 437
Self-citationMicromachine‐Enabled Capture and Isolation of Cancer Cells in Complex Media
Balasubramanian, S., Kagan, D., Jack Hu, C., Campuzano, S., Lobo‐Castañon, M. J., Lim, N., Kang, D. Y., Zimmerman, M., Zhang, L., & Wang, J. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201100115 · Cited by 426
Self-citationMagnetically Powered Flexible Metal Nanowire Motors
Gao, W., Sattayasamitsathit, S., Manesh, K. M., Weihs, D., & Wang, J. (2010) · Journal of the American Chemical Society · doi:10.1021/ja1072349 · Cited by 416
Self-citationSolovev, A. A., Xi, W., Gracias, D. H., Harazim, S. M., Deneke, C., Sanchez, S., & Schmidt, O. G. (2012) · ACS Nano · doi:10.1021/nn204762w · Cited by 393
Hydrogen-Bubble-Propelled Zinc-Based Microrockets in Strongly Acidic Media
Gao, W., Uygun, A., & Wang, J. (2012) · Journal of the American Chemical Society · doi:10.1021/ja210874s · Cited by 389
Self-citationCarbon-Nanotube-Induced Acceleration of Catalytic Nanomotors
Laocharoensuk, R., Burdick, J., & Wang, J. (2008) · ACS Nano · doi:10.1021/nn800154g · Cited by 349
Self-citationKagan, D., Benchimol, M. J., Claussen, J. C., Chuluun‐Erdene, E., Esener, S., & Wang, J. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201201902 · Cited by 336
Self-citationBacterial Isolation by Lectin-Modified Microengines
Campuzano, S., Orozco, J., Kagan, D., Guix, M., Gao, W., Sattayasamitsathit, S., Claussen, J. C., Merkoçi, A., & Wang, J. (2012) · Nano Letters · doi:10.1021/nl203717q · Cited by 330
Self-citationZhang, L., Petit, T., Lu, Y., Kratochvil, B. E., Peyer, K. E., Pei, R., Lou, J., & Nelson, B. J. (2010) · ACS Nano · doi:10.1021/nn101861n · Cited by 296
Mallouk, T. E., & Sen, A. (2009) · Scientific American · doi:10.1038/scientificamerican0509-72 · Cited by 293
Rapid Delivery of Drug Carriers Propelled and Navigated by Catalytic Nanoshuttles
Kagan, D., Laocharoensuk, R., Zimmerman, M., Clawson, C., Balasubramanian, S., Kang, D., Bishop, D., Sattayasamitsathit, S., Zhang, L., & Wang, J. (2010) · Small · doi:10.1002/smll.201001257 · Cited by 290
Self-citationMano, N., & Heller, A. (2005) · Journal of the American Chemical Society · doi:10.1021/ja053937e · Cited by 285
Controlled manipulation of multiple cells using catalytic microbots
Sanchez, S., Solovev, A. A., Schulze, S., & Schmidt, O. G. (2011) · Chem. Commun. · doi:10.1039/c0cc04126b · Cited by 256
Motion Control at the Nanoscale
Wang, J., & Manesh, K. M. (2010) · Small · doi:10.1002/smll.200901746 · Cited by 241
Self-citationAutonomous propulsion of carbon nanotubes powered by a multienzyme ensemble
Pantarotto, D., Browne, W. R., & Feringa, B. L. (2008) · Chem. Commun. · doi:10.1039/b715310d · Cited by 219
Fuel for Thought: Chemically Powered Nanomotors Out-Swim Nature’s Flagellated Bacteria
Mirkovic, T., Zacharia, N. S., Scholes, G. D., & Ozin, G. A. (2010) · ACS Nano · doi:10.1021/nn100669h · Cited by 188
Selective Trapping and Manipulation of Microscale Objects Using Mobile Microvortices
Petit, T., Zhang, L., Peyer, K. E., Kratochvil, B. E., & Nelson, B. J. (2011) · Nano Letters · doi:10.1021/nl2032487 · Cited by 176
Motion-driven sensing and biosensing using electrochemically propelled nanomotors
Campuzano, S., Kagan, D., Orozco, J., & Wang, J. (2011) · The Analyst · doi:10.1039/c1an15599g · Cited by 161
Self-citationPolymer-based tubular microbots: role of composition and preparation
Gao, W. F., Sattayasamitsathit, S., Uygun, A., Pei, A., Ponedal, A., & Wang, J. (2012) · Nanoscale · doi:10.1039/c2nr30138e · Cited by 150
Self-citationThe role of ultrasound in molecular imaging
Liang, H.-D., & Blomley, M. J. K. (2003) · British Journal of Radiology · doi:10.1259/bjr/57063872 · Cited by 149
Cargo-towing synthetic nanomachines: Towards active transport in microchip devices
Wang, J. (2012) · Lab on a Chip · doi:10.1039/c2lc00003b · Cited by 147
Self-citationTargeted cargo delivery using a rotating nickel nanowire
Zhang, L., Petit, T., Peyer, K. E., & Nelson, B. J. (2012) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2012.03.002 · Cited by 137
Cited by
The Environmental Impact of Micro/Nanomachines: A Review
Gao, W., & Wang, J. (2014) · ACS Nano · doi:10.1021/nn500077a · Cited by 594
Self-citationMaterials learning from life: concepts for active, adaptive and autonomous molecular systems
Merindol, R., & Walther, A. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00738d · Cited by 533
Dual-responsive biohybrid neutrobots for active target delivery
Zhang, H., Li, Z., Gao, C., Fan, X., Pang, Y., Li, T., Wu, Z., Xie, H., & He, Q. (2021) · Science Robotics · doi:10.1126/scirobotics.aaz9519 · Cited by 518
Bioinspired Helical Microswimmers Based on Vascular Plants
Gao, W., Feng, X., Pei, A., Kane, C. R., Tam, R., Hennessy, C., & Wang, J. (2014) · Nano Letters · doi:10.1021/nl404044d · Cited by 380
Self-citationTargeting 3D Bladder Cancer Spheroids with Urease-Powered Nanomotors
Hortelão, A. C., Carrascosa, R., Murillo-Cremaes, N., Patiño, T., & Sánchez, S. (2019) · ACS Nano · doi:10.1021/acsnano.8b06610 · Cited by 287
Metadata
- Authors
- Wang, J., & Gao, W.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-07-06
- Volume
- 6
- Issue
- 7
- Pages
- 5745-5751
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2054680198
- Cited by
- 668
- References
- 37
- FWCI
- 42.36
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.