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Cited by 333

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Temperature: The “Ignored” Factor at the NanoBio Interface

Mahmoudi, Morteza, Abdelmonem, Abuelmagd M., Behzadi, Shahed, Clement, Joachim H., Dutz, Silvio, Ejtehadi, Mohammad R., Hartmann, Raimo, Kantner, Karsten, Linne, Uwe, Maffre, Pauline, Metzler, Scott, Moghadam, Mojhgan K., Pfeiffer, Christian, Rezaei, Meisam, Ruiz-Lozano, Pilar, Serpooshan, Vahid, Shokrgozar, Mohammad A., Nienhaus, G. Ulrich, Parak, Wolfgang J.·2013·ACS Nano

Abstract

Upon incorporation of nanoparticles (NPs) into the body, they are exposed to biological fluids, and their interaction with the dissolved biomolecules leads to the formation of the so-called protein corona on the surface of the NPs. The composition of the corona plays a crucial role in the biological fate of the NPs. While the effects of various physicochemical parameters on the composition of the corona have been explored in depth, the role of temperature upon its formation has received much less attention. In this work, we have probed the effect of temperature on the protein composition on the surface of a set of NPs with various surface chemistries and electric charges. Our results indicate that the degree of protein coverage and the composition of the adsorbed proteins on the NPs' surface depend on the temperature at which the protein corona is formed. Also, the uptake of NPs is affected by the temperature. Temperature is, thus, an important parameter that needs to be carefully controlled in quantitative studies of bionano interactions.

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Metadata

Authors
Mahmoudi, M., Abdelmonem, A. M., Behzadi, S., Clement, J. H., Dutz, S., Ejtehadi, M. R., Hartmann, R., Kantner, K., Linne, U., Maffre, P., Metzler, S., Moghadam, M. K., Pfeiffer, C., Rezaei, M., Ruiz-Lozano, P., Serpooshan, V., Shokrgozar, M. A., Nienhaus, G. U., & Parak, W. J.
Venue
ACS Nano
Published
2013-07-10
Volume
7
Issue
8
Pages
6555-6562
ISSN
  • 1936-0851 (ISSN-L)
  • 1936-086X
OpenAlex
W1989090339
Cited by
333
References
6
FWCI
11.98
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Temperature: The “Ignored” Factor at the NanoBio Interface. https://app.cochat.ai/papers/10.1021/nn305337c
The paper
Mahmoudi, M., Abdelmonem, A. M., Behzadi, S., Clement, J. H., Dutz, S., Ejtehadi, M. R., Hartmann, R., Kantner, K., Linne, U., Maffre, P., Metzler, S., Moghadam, M. K., Pfeiffer, C., Rezaei, M., Ruiz-Lozano, P., Serpooshan, V., Shokrgozar, M. A., Nienhaus, G. U., & Parak, W. J. (2013). Temperature: The “Ignored” Factor at the NanoBio Interface. ACS Nano. https://doi.org/10.1021/nn305337c

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.