The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
A-Type Proanthocyanidin Trimers from Cranberry that Inhibit Adherence of Uropathogenic P-Fimbriated Escherichia coli
Abstract
Three proanthocyanidin trimers possessing A-type interflavanoid linkages, epicatechin-(4beta-->6)-epicatechin-(4beta-->8, 2beta-->O-->7)-epicatechin (4), epicatechin-(4beta-->8, 2beta-->O-->7)-epicatechin-(4beta-->8)-epicatechin (5), and epicatechin-(4beta-->8)-epicatechin-(4beta-->8, 2beta-->O-->7)-epicatechin (6), were isolated from the ripe fruits of Vaccinium macrocarpon (cranberry) and prevented adherence of P-fimbriated Escherichia coli isolates from the urinary tract to cellular surfaces containing alpha-Gal(1-->4)beta-Gal receptor sequences similar to those on uroepithelial cells. The structure of 4 was elucidated by a combination of spectroscopic methods and acid-catalyzed degradation with phloroglucinol. Also isolated were the weakly active epicatechin-(4beta-->8, 2beta-->O-->7)-epicatechin (procyanidin A2) (3) and the inactive monomer epicatechin (1) and the inactive dimer epicatechin-(4beta-->8)-epicatechin (procyanidin B2) (2).
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Cites
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Reduction of Bacteriuria and Pyuria After Ingestion of Cranberry Juice
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THE PkANTIGEN AS RECEPTOR FOR THE HAEMAGGLUTININ OF PYELONEPHRITIC ESCHERICHIA COLI
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Cited by
Anhê, F. F., Roy, D., Pilon, G., Dudonné, S., Matamoros, S., Varin, T. V., Garofalo, C., Moine, Q., Desjardins, Y., Levy, E., et al. (2015) · Gut · doi:10.1136/gutjnl-2014-307142 · Cited by 1,137
Overview of Dietary Flavonoids: Nomenclature, Occurrence and Intake
Beecher, G. R. (2003) · The Journal of Nutrition · doi:10.1093/jn/133.10.3248s · Cited by 909
Berry Phenolics: Antimicrobial Properties and Mechanisms of Action Against Severe Human Pathogens
Nohynek, L. J., Alakomi, H.-L., Kähkönen, M. P., Heinonen, M., Helander, I. M., Oksman-Caldentey, K.-M., & Puupponen-Pimiä, R. H. (2006) · Nutrition and Cancer · doi:10.1207/s15327914nc5401_4 · Cited by 537
Anti-adhesion therapy of bacterial diseases: prospects and problems
Ofek, I., Hasty, D. L., & Sharon, N. (2003) · FEMS Immunology & Medical Microbiology · doi:10.1016/s0928-8244(03)00228-1 · Cited by 444
Gu, L., Kelm, M., Hammerstone, J. F., Beecher, G., Cunningham, D., Vannozzi, S., & Prior, R. L. (2002) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf020214v · Cited by 417
Metadata
- Authors
- Foo, L. Y., Lu, Y., Howell, A. B., & Vorsa, N.
- Venue
- Journal of Natural Products
- Publisher
- American Chemical Society (ACS)
- Published
- 2000-07-28
- Volume
- 63
- Issue
- 9
- Pages
- 1225-1228
- ISSN
- 0163-3864 (ISSN-L)
- 1520-6025
- OpenAlex
- W2038566784
- Cited by
- 431
- References
- 11
- FWCI
- 4.80
- Type
- journal article
- Language
- en
- Open access
- closed
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