Cited by 41Phytochemical Studies and BioactivitiesPhytochemistry and Biological ActivitiesBioactive Natural Diterpenoids Research

Ecdysteroids of Vitex scabra Stem Bark

Suksamrarn, Apichart, Kumpun, Saowanee, Yingyongnarongkul, Boon-ek·2002·Journal of Natural Products

Abstract

Two new ecdysteroids, 24-epi-pinnatasterone (1) and scabrasterone (2), together with 11 known ecdysteroids, calonysterone, pterosterone, 24-epi-makisterone A, 20-hydroxyecdysone (3), polypodine B, ajugasterone C, pinnatasterone (4), 11alpha-hydroxyecdysone, 24-epi-abutasterone, 20,26-dihydroxyecdysone, and turkesterone (5), were isolated from the stem bark of Vitex scabra. This plant species contained a very high concentration (1.8%) of 3 and thus provided a good source of this parent ecdysteroid and related rare ecdysteroids. Compounds 1 and 2 exhibited very low moulting activity in the Musca bioassay. The low biological activity of these two ecdysteroids was in agreement with those of other 22-deoxyecdysteroids.

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Crossref · 10.1021/np020199o

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14 of 14 references verified0 citation errors · 0 not checkable

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Authors
Suksamrarn, A., Kumpun, S., & Yingyongnarongkul, B.-E.
Affiliations
Ramkhamhaeng University (TH)
Venue
Journal of Natural Products
Published
2002-09-05
Volume
65
Issue
11
Pages
1690-1692
ISSN
  • 0163-3864 (ISSN-L)
  • 1520-6025
OpenAlex
W2337120619
Cited by
41
References
14
Citations by year
2026: 2 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 3 · 2019: 1 · 2018: 2 · 2017: 1 · 2016: 1 · 2013: 1 · 2012: 12
FWCI
0.12
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Natural Products (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Phytochemical Studies and Bioactivities
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bioactive Natural Diterpenoids Research
Keywords
ecdysteroids, stem bark, 20-hydroxyecdysone, natural product isolation
MeSH terms
Acetylation, Chromatography, Thin Layer, Plants, Medicinal, Thailand, Molecular Structure, Plant Stems, Nuclear Magnetic Resonance, Biomolecular, Vitex, Plant Bark, Ecdysteroids, Musa

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