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Antioxidant and Antiinflammatory Activities of Anthocyanins and Their Aglycon, Cyanidin, from Tart Cherries
Abstract
The anthocyanins ( 1 − 3 ) and cyanidin isolated from tart cherries exhibited in vitro antioxidant and antiinflammatory activities comparable to commercial products. The inhibition of lipid peroxidation of anthocyanins 1 − 3 and their aglycon, cyanidin, were 39, 70, 75, and 57%, respectively, at 2-mM concentrations. The antioxidant activities of 1 - 3 and cyanidin were comparable to the antioxidant activities of tert -butylhydroquinone and butylated hydroxytoluene and superior to vitamin E at 2-mM concentrations. In the antiinflammatory assay, cyanidin gave IC 50 values of 90 and 60 mM, respectively, for prostaglandin H endoperoxide synthase-1 and prostaglandin H endoperoxide synthase-2 enzymes.
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Cited by
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Dai, Y., Rozema, E., Verpoorte, R., & Choi, Y. H. (2016) · Journal of Chromatography A · doi:10.1016/j.chroma.2016.01.037 · Cited by 416
Howatson, G., McHugh, M. P., Hill, J. A., Brouner, J., Jewell, A. P., Van Someren, K. A., Shave, R. E., & Howatson, S. A. (2010) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/j.1600-0838.2009.01005.x · Cited by 394
Kang, S.-Y., Seeram, N. P., Nair, M. G., & Bourquin, L. D. (2003) · Cancer Letters · doi:10.1016/s0304-3835(02)00583-9 · Cited by 349
Self-citationShih, P.-H., Yeh, C.-T., & Yen, G.-C. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf071933i · Cited by 334
Metadata
- Authors
- Wang, H., Nair, M. G., Strasburg, G. M., Chang, Y.-C., Booren, A. M., Gray, J. I., & DeWitt, D. L.
- Venue
- Journal of Natural Products
- Publisher
- American Chemical Society (ACS)
- Published
- 1999-01-28
- Volume
- 62
- Issue
- 2
- Pages
- 294-296
- ISSN
- 0163-3864 (ISSN-L)
- 1520-6025
- OpenAlex
- W4322702936
- Cited by
- 499
- References
- 0
- FWCI
- 3.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wang, H., Nair, M. G., Strasburg, G. M., Chang, Y.-C., Booren, A. M., Gray, J. I., & DeWitt, D. L. (1999). Antioxidant and Antiinflammatory Activities of Anthocyanins and Their Aglycon, Cyanidin, from Tart Cherries. Journal of Natural Products. https://doi.org/10.1021/np980501m
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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