The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Analytical Strategies in Metabonomics
Abstract
To perform metabonomics investigations, it is necessary to generate comprehensive metabolite profiles for complex samples such as biofluids and tissue/tissue extracts. Analytical technologies that can be used to achieve this aim are constantly evolving, and new developments are changing the way in which such profiles' metabolite profiles can be generated. Here, the utility of various analytical techniques for global metabolite profiling, such as, e.g., 1 H NMR, MS, HPLC-MS, and GC-MS, are explored and compared. Keywords: global metabolite profiling • metabotyping • metabonomics • metabolomics • spectroscopic analysis • separations • hyphenation
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Citations
Cites
Gut microorganisms, mammalian metabolism and personalized health care
Nicholson, J. K., Holmes, E., & Wilson, I. D. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1152 · Cited by 945
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Cited by
Gut microbiota functions: metabolism of nutrients and other food components
Rowland, I., Gibson, G., Heinken, A., Scott, K., Swann, J., Thiele, I., & Tuohy, K. (2018) · European Journal of Nutrition · doi:10.1007/s00394-017-1445-8 · Cited by 2,878
Beckonert, O., Keun, H. C., Ebbels, T. M. D., Bundy, J., Holmes, E., Lindon, J. C., & Nicholson, J. K. (2007) · Nature Protocols · doi:10.1038/nprot.2007.376 · Cited by 2,109
Human metabolic phenotype diversity and its association with diet and blood pressure
Holmes, E., Loo, R. L., Stamler, J., Bictash, M., Yap, I. K. S., Chan, Q., Ebbels, T., De Iorio, M., Brown, I. J., Veselkov, K. A., et al. (2008) · Nature · doi:10.1038/nature06882 · Cited by 1,054
Dona, A. C., Jiménez, B., Schäfer, H., Humpfer, E., Spraul, M., Lewis, M. R., Pearce, J. T. M., Holmes, E., Lindon, J. C., & Nicholson, J. K. (2014) · Analytical Chemistry · doi:10.1021/ac5025039 · Cited by 540
LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics
Theodoridis, G., Gika, H. G., & Wilson, I. D. (2008) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2008.01.008 · Cited by 371
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Metadata
- Authors
- Lenz, E. M., & Wilson, I. D.
- Venue
- Journal of Proteome Research
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-12-13
- Volume
- 6
- Issue
- 2
- Pages
- 443-458
- ISSN
- 1535-3893 (ISSN-L)
- 1535-3907
- OpenAlex
- W1978461542
- Cited by
- 530
- References
- 1
- FWCI
- 12.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lenz, E. M., & Wilson, I. D. (2007). Analytical Strategies in Metabonomics. Journal of Proteome Research. https://doi.org/10.1021/pr0605217
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
