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Cited by 160

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Interfacing Carbon Nanotubes with Living Mammalian Cells and Cytotoxicity Issues

Cui, Hui-Fang, Vashist, Sandeep Kumar, Al-Rubeaan, Khalid, Luong, John H. T., Sheu, Fwu-Shan·2010·Chemical Research in Toxicology

Abstract

The unique structures and properties of carbon nanotubes (CNTs) have attracted extensive investigations for many applications, such as those in the field of biomedical materials and devices, biosensors, drug delivery, and tissue engineering. Anticipated large-scale productions for numerous diversified applications of CNTs might adversely affect the environment and human health. For successful applications in the biomedical field, the issue of interfacing between CNTs and mammalian cells in vitro needs to be addressed before in vivo studies can be carried out systematically. We review the important studies pertaining to the internalization of CNTs into the cells and the culturing of cells on the CNT-based scaffold or support materials. The review will focus on the description of a variety of factors affecting CNT cytotoxicity: type of CNTs, impurities, lengths of CNTs, aspect ratios, dispersion, chemical modification, and assaying methods of cytotoxicity.

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Crossref · 10.1021/tx100050h

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Metadata

Authors
Cui, H.-F., Vashist, S. K., Al-Rubeaan, K., Luong, J. H. T., & Sheu, F.-S.
Venue
Chemical Research in Toxicology
Published
2010-04-19
Volume
23
Issue
7
Pages
1131-1147
ISSN
  • 0893-228X (ISSN-L)
  • 1520-5010
OpenAlex
W2070769462
Cited by
160
References
5
FWCI
9.10
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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