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Cited by 31Neuroscience and Neuropharmacology ResearchNeural dynamics and brain functionConnexins and lens biology

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Considerations on the astroglial architecture and the columnar organization of the cerebral cortex.

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Reisin, Hernán D., Colombo, Jorge A.·2002·Cellular and Molecular Neurobiology
DOI 10.1023/a:1021892521180PMC PMC11533786
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Abstract

Present knowledge on astroglial roles in brain organization and function indicates that these cells can regulate the extracellular ionic composition and modulate neuronal activity. In this regard, the "panglial synctium" formed by electrically and chemically coupled stellate astrocytes ("general mammalian" architecture) is believed to provide an intracellular pathway for the redistribution of ions and molecules within the cerebral cortex. Long astroglial interlaminar processes ("primate-specific" architecture) that run parallel to apical dendrites in the cerebral cortex of primates, may provide additional properties to the glial participation in cortical physiology and function. Since these processes are exclusively present within the primate order, functional models of cortical computations for these species should incorporate the astroglial interlaminar architecture in addition to the panglial synctium. This study analyzes possible implications of interlaminar astroglial processes, for the regulation of the extracellular ionic composition and segregation of functional columns in the cerebral cortex.

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  • Evidence supports a glial columnar organization, challenging the traditional perception of astrocytes as part of a horizontal cytoarchitecture forming a panglial syncytium.

    “this new view of an active milieu in which the glia is as much fundamental as neurons is supported by evidence of a glial columnar organization, challenging the traditional perception of astrocytes as part of a horizontal cytoarchitecture forming a panglial syncytium”

    From Interlaminar and varicose-projection astrocytes: toward a new understanding of the primate brain (2024) · cites this paper as Hern’ et al., 2002

    The Introduction and General Morphological Aspects of Interlaminar Glia describe vertical astroglial processes in primate cortex that challenge the conventional net-like panglial-syncytium model. But Possible Impact of Interlaminar Glia on Modular Function calls their role in columnar organization speculative, and the Conclusions say its functional effect remains unconfirmed. The claim overstates the evidence and omits the primate-cortex qualification; page numbers are unavailable in our copy. (LLM, conf=0.84)

    Experimental — accuracy not yet measured

  • The formation of fascicules in a honeycomb pattern in tangential sections of the human brain suggests a role for ILAs in the columnization of Ca2+ waves around granular neurons, leading to cylindrical-like waves that follow the morphology of ILAs long processes.

    “The formation of fascicules in a honeycomb pattern, visualized in tangential sections of the human brain (Colombo et al., 1998), suggests a role in the “columnization” of Ca2+ waves around granular neurons, leading to cylindrical-like waves that follow the morphology of ILAs long processes (Colombo and Reisin, 2004; Hern’ et al., 2002).”

    From Interlaminar and varicose-projection astrocytes: toward a new understanding of the primate brain (2024) · cites this paper as Hern’ et al., 2002

    The Interlaminar Palisade section proposes that fasciculated interlaminar processes could generate cylindrical-like Ca²⁺ waves along their long processes and provide a columnar-like organization for tangential Ca²⁺ signals. It presents this as a hypothetical mechanism, not an observed effect, and does not locate the waves specifically around granular neurons. The citing sentence attributes the tangential-section observation to Colombo et al. (1998), rather than to this paper. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

  • The ends of longer ILA processes are varicose-like, creating a club-ending that may increase membrane surface availability.

    “The ends of the longer processes is also varicose-like, creating a club-ending that may increase membrane surface availability”

    From Interlaminar and varicose-projection astrocytes: toward a new understanding of the primate brain (2024) · cites this paper as Hern’ et al., 2002

  • Taken together, these data suggest a sensitivity of ILAs to stressful conditions.

    “Taken together, these data suggest a sensitivity of ILAs to stressful conditions (Hern’ et al., 2002).”

    From Interlaminar and varicose-projection astrocytes: toward a new understanding of the primate brain (2024) · cites this paper as Hern’ et al., 2002

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Citations

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Research works printed but not linked: 33

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Metadata

Authors
Reisin, H. D., & Colombo, J. A.
Affiliations
Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
Corresponding author
Colombo, Jorge A.
ORCID
Colombo, Jorge A.
Venue
Cellular and Molecular Neurobiology
Publisher
Springer Science and Business Media LLC
Published
2002-12
Volume
22
Issue
5-6
Pages
633-644
ISSN
  • 0272-4340 (ISSN-L)
  • 1573-6830
DOI
10.1023/a:1021892521180
PMC
PMC11533786
OpenAlex
W95510559
Cited by
31
References
4
Citations by year
2024: 1 · 2020: 1 · 2018: 3 · 2017: 1 · 2016: 2 · 2014: 3 · 2012: 3
FWCI
0.18
Type
journal article
Language
en
Open access
Licence
Locations
  • Cellular and Molecular Neurobiology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Consejo Nacional de Investigaciones Científicas y Técnicas
  • Fundación Bunge y Born
  • Fondo para la Investigación Científica y Tecnológica
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Connexins and lens biology
Keywords
astrocytes, cerebral cortex, columnar organization, stellate astrocytes, primate cerebral cortex, cortical physiology
MeSH terms
Animals, Astrocytes, Cell Communication, Cerebral Cortex, Extracellular Space, Humans, Ions, Nerve Net, Synaptic Transmission, Neurons, Primates

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