Src family kinases in tumor progression and metastasis

CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES

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Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

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Three-dimensional structure of the tyrosine kinase c-Src

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DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA

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Regulation, substrates and functions of src

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Crystal structure of the Src family tyrosine kinase Hck

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A SARCOMA OF THE FOWL TRANSMISSIBLE BY AN AGENT SEPARABLE FROM THE TUMOR CELLS

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Tyrosine kinase/p21ras/MAP‐kinase pathway activation by estradiol‐receptor complex in MCF‐7 cells.

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Identification of a transformation-specific antigen induced by an avian sarcoma virus

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Role of Src expression and activation in human cancer

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Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

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Phenylpyrazalopyrimidines as Tyrosine Kinase Inhibitors: Synthesis, Antiproliferative Activity, and Molecular Simulations

Chhikara, B. S., Ashraf, S., Mozaffari, S., Jeans, N. S., Mandal, D., Tiwari, R. K., Ul‐Haq, Z., & Parang, K. (2020) · Molecules · doi:10.3390/molecules25092135 · Cited by 20

PAR-4 as a possible new target for pancreatic cancer therapy

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One-pot regioselective synthesis of tetrahydroindazolones and evaluation of their antiproliferative and Src kinase inhibitory activities

Rao, V. K., Chhikara, B. S., Tiwari, R. K., Shirazi, A. N., Parang, K., & Kumar, A. (2011) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2011.10.124 · Cited by 20

c-Src Is the Primary Signaling Mediator of Polychlorinated Biphenyl–Induced Interleukin-8 Expression in a Human Microvascular Endothelial Cell Line

Eum, S. Y., Rha, G. B., Hennig, B., & Toborek, M. J. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj194 · Cited by 20

Stimulation of hTAFII68 (NTD)‐mediated transactivation by v‐Src

Lee, H. J., Kim, S., Pelletier, J., & Kim, J. (2004) · FEBS Letters · doi:10.1016/s0014-5793(04)00314-x · Cited by 20

MicroRNAs as the fine-tuners of Src oncogenic signalling

Oneyama, C., & Okada, M. (2015) · The Journal of Biochemistry · doi:10.1093/jb/mvv036 · Cited by 19

Emerging Roles of YES1 in Cancer: The Putative Target in Drug Resistance

Kook, E., Chun, K., & Kim, D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031450 · Cited by 18

Suppression of E-Cadherin Function Drives the Early Stages of Ras-Induced Squamous Cell Carcinoma through Upregulation of FAK and Src

Alt‐Holland, A., Sowalsky, A. G., Szwec-Levin, Y., Shamis, Y., Hatch, H., Feig, L. A., & Garlick, J. A. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.188 · Cited by 20

17β-Estradiol inhibition of IL-6–Src and Cas and paxillin pathway suppresses human mesenchymal stem cells–mediated gastric cancer cell motility

Liu, C., Kuo, F., Hu, H., Chen, C., Huang, Y., Cheng, K., Yokoyama, K. K., Wu, D., Hsieh, S., & Kuo, C. (2014) · Translational research · doi:10.1016/j.trsl.2014.04.009 · Cited by 19

17β-Estradiol Inhibits Mesenchymal Stem Cells-Induced Human AGS Gastric Cancer Cell Mobility via Suppression of CCL5- Src/Cas/Paxillin Signaling Pathway

Kuo, C., Liu, C., Lu, C.-Y., Hu, H., Kuo, F.-C., Liou, Y.-S., Yang, Y., Hsieh, M.-C., Lee, O. K., Wu, D., et al. (2014) · International Journal of Medical Sciences · doi:10.7150/ijms.6851 · Cited by 19

Supramolecular alleviation of cardiotoxicity of a small-molecule kinase inhibitor

Yang, X., Huang, Q., Bardelang, D., Wang, C., Lee, S. M., & Wang, R. (2017) · Organic & Biomolecular Chemistry · doi:10.1039/c7ob01505d · Cited by 19

Connexin 32 affects doxorubicin resistance in hepatocellular carcinoma cells mediated by Src/FAK signaling pathway

Yu, M., Zou, Q., Wu, X.-X., Han, G., & Tong, X. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.09.065 · Cited by 19

SRC inhibition prevents P-cadherin mediated signaling and function in basal-like breast cancer cells

Ribeiro, A. S., Nobre, A. R., Mendes, N. M., Almeida, J., Vieira, A. F., Sousa, B., Carvalho, F. A., Monteiro, J., Polónia, A., Fonseca, M. B., et al. (2018) · Cell Communication and Signaling · doi:10.1186/s12964-018-0286-2 · Cited by 19

Role of microRNA‑150‑5p/SRCIN1 axis in the progression of breast cancer

Lu, Q., Guo, Z., & Qian, H. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.7206 · Cited by 19

The SRC Inhibitor Dasatinib Induces Stem Cell-Like Properties in Head and Neck Cancer Cells that are Effectively Counteracted by the Mithralog EC-8042

Hermida‐Prado, F., Villaronga, M. Á., Granda‐Díaz, R., Del-Río-Ibisate, N., Santos, L. M., Hermosilla, M. A., Oro, P., Allonca, E., Agorreta, J., Garmendia, I., et al. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8081157 · Cited by 19

Antitumor effects of Dasatinib on laryngeal squamous cell carcinoma in vivo and in vitro

Song, Y., Sun, X., Bai, W., & Ji, W. (2013) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-013-2394-3 · Cited by 19

Significant association of SRC protein expression with the progression, recurrence, and prognosis of oral squamous cell carcinoma in Taiwan

Cheng, S., Kok, S., Lee, J., Kuo, M. Y., Cheng, S.-L., Huang, Y., Chen, H., Chang, H., & Chiang, C. (2011) · Head & Neck · doi:10.1002/hed.21923 · Cited by 19

The Interaction of Src Kinase with β3 Integrin Tails: A Potential Therapeutic Target in Thrombosis and Cancer

Huveneers, S., & Danen, E. H. J. (2010) · The Scientific World JOURNAL · doi:10.1100/tsw.2010.114 · Cited by 19

Dasatinib reduces 5-Fu-triggered apoptosis in colon carcinoma by directly modulating Src-dependent caspase-9 phosphorylation

Fu, Y., Yang, G., Xue, P., Guo, L., Yin, Y., Ye, Z., Peng, S., Qin, Y., Duan, Q., & Zhu, F. (2018) · Cell Death Discovery · doi:10.1038/s41420-018-0062-5 · Cited by 19

Src Tyrosine Kinase Inhibitor, M475271, Suppresses Subcutaneous Growth and Production of Lung Metastasis Via Inhibition of Proliferation, Invasion, and Vascularization of Human Lung Adenocarcinoma Cells

Zheng, R., Yano, S., Matsumori, Y., Nakataki, E., Muguruma, H., Yoshizumi, M., & Sone, S. (2005) · Clinical & Experimental Metastasis · doi:10.1007/s10585-005-7768-5 · Cited by 19

PIKE GTPase are phosphoinositide‐3‐kinase enhancers, suppressing programmed cell deathPIKE GTPase are phosphoinositide‐3‐kinase enhancers, suppressing programmed cell death

Chan, C. B., & Ye, K. (2007) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2007.00014.x · Cited by 19

Src Cooperates with Oncogenic Ras in Tumourigenesis via the JNK and PI3K Pathways in Drosophila epithelial Tissue

Poon, C. L. C., Brumby, A. M., & Richardson, H. E. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19061585 · Cited by 19

MicroRNA-3607 inhibits the tumorigenesis of colorectal cancer by targeting DDI2 and regulating the DNA damage repair pathway

Lei, L., Zhao, X., Liu, S., Cao, Q., Yan, B., & Yang, J. (2019) · Apoptosis · doi:10.1007/s10495-019-01549-5 · Cited by 18

Regulation of Src tumor activity by its N-terminal intrinsically disordered region

Aponte, E., Lafitte, M., Sirvent, A., Simon, V., Barbery, M., Fourgous, E., Boublik, Y., Maffei, M., Armand, F., Hamelin, R., et al. (2022) · Oncogene · doi:10.1038/s41388-021-02092-x · Cited by 17

Comparative Analysis of Dasatinib Effect between 2D and 3D Tumor Cell Cultures

Sabetta, S., Vecchiotti, D., Clementi, L., Nolfi, M. D. V., Zazzeroni, F., & Angelucci, A. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15020372 · Cited by 20

Src activity is modulated by oxaliplatin and correlates with outcomes after hepatectomy for metastatic colorectal cancer

Kopetz, S., Morris, V. K., Parikh, N. U., Overman, M. J., Jiang, Z.-Q., Maru, D. M., Elvin, P., & Gallick, G. E. (2014) · BMC Cancer · doi:10.1186/1471-2407-14-660 · Cited by 18

Aldolase triggers metabolic reprogramming in colorectal cancer in hypoxia and stiff desmoplastic microenvironments

Huang, H.-C., Lin, W., Lim, S., Yeh, C., Yen, T., Alison, M. R., & Chen, C. (2020) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2020.110969 · Cited by 18

Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo

Al‐Asmakh, M., Bawadi, H. A., Hamdan, M. M., Gupta, I., Kheraldine, H., Jabeen, A., Rizeq, B. R., & Moustafa, A. A. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.111134 · Cited by 20

Methionine restriction breaks obligatory coupling of cell proliferation and death by an oncogene Src in Drosophila

Nishida, H., Okada, M., Yang, L., Takano, T., Tabata, S., Soga, T., Ho, D. M., Chung, J., Minami, Y., & Yoo, S. K. (2021) · eLife · doi:10.7554/elife.59809 · Cited by 18

Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts

Harrach, S., Edemir, B., Schmidt‐Lauber, C., Pap, T., Bertrand, J., & Ciarimboli, G. (2017) · Scientific Reports · doi:10.1038/s41598-017-01438-4 · Cited by 18

Local light-activation of the Src oncoprotein in an epithelial monolayer promotes collective extrusion

Moitrier, S., Pricoupenko, N., Kerjouan, A., Oddou, C. I., Destaing, O., Battistella, A., Silberzan, P., & Bonnet, I. (2019) · Communications Physics · doi:10.1038/s42005-019-0198-5 · Cited by 21

Structure‐based design of novel nonpeptide inhibitors of the Src SH2 domain: Phosphotyrosine mimetics exploiting multifunctional group replacement chemistry*

Sundaramoorthi, R., Kawahata, N. H., Yang, M. G., Shakespeare, W. C., Metcalf, C. A., Wang, Y., Merry, T. J., Eyermann, C. J., Bohacek, R. S., Narula, S. S., et al. (2003) · Biopolymers · doi:10.1002/bip.10600 · Cited by 18

Divalent cations influence colon cancer cell adhesion in a murine transplantable tumor model

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Tissue transglutaminase and its role in human cancer progression.

Li, B., Cerione, R., & Antonyak, M. A. (2011) · Advances in Enzymology and Related Subjects · doi:10.1002/9781118105771.ch6 · Cited by 19

Emerging novel therapies in the treatment of castrate-resistant prostate cancer

Abdulla, A., & Kapoor, A. (2011) · Canadian Urological Association Journal · doi:10.5489/cuaj.10160 · Cited by 18

Functional characterization of FBXL7 as a novel player in human cancers

Wang, Y., Shen, X. Z., Gong, L., Zhao, Y., & Xiong, X. (2022) · Cell Death Discovery · doi:10.1038/s41420-022-01143-w · Cited by 17

Src is a novel potential off‐target of RXR agonists, 9‐cis‐UAB30 and Targretin, in human breast cancer cells

Kim, M., Lim, D. Y., Kim, J., Chen, H., Lubet, R. A., Dong, Z., & Bode, A. M. (2014) · Molecular Carcinogenesis · doi:10.1002/mc.22232 · Cited by 17

Classification of Src Kinase Inhibitors Based on Support Vector Machine

Zhu, J., Lu, W., Liu, L., Gu, T., & Niu, B. (2009) · QSAR & Combinatorial Science · doi:10.1002/qsar.200860105 · Cited by 16

Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer development

Hao, Q., Lu, X., Liu, N., Xue, X., Li, M., Zhang, C., Qin, X., Li, W., Shu, Z., Song, B., et al. (2013) · BMB Reports · doi:10.5483/bmbrep.2013.46.6.208 · Cited by 17

3D-QSAR study of Chk1 kinase inhibitors based on docking

Zhao, L., Liu, Y., Hu, S., & Zhang, H. (2012) · Journal of Molecular Modeling · doi:10.1007/s00894-012-1363-x · Cited by 17

Computational approaches for identifying potential inhibitors on targeting protein interactions in drug discovery

Kanakaveti, V., Anusuya, S., Ramakrishnan, C. V., Anoosha, P., Sakthivel, R., Rayala, S. K., & Gromiha, M. M. (2020) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2019.11.013 · Cited by 19

Antiangiogenic effect of dasatinib in murine models of oxygen-induced retinopathy and laser-induced choroidal neovascularization.

Seo, S., & Suh, W. (2017) · Europe PMC (PubMed Central) · Cited by 17

Src Kinase and Pancreatic Cancer

Hilbig, A. (2007) · Springer eBooks · doi:10.1007/978-3-540-71279-4_19 · Cited by 17

c‐Src expression is predictive of poor prognosis in breast cancer patients with bone metastasis, but not in patients with visceral metastasis

Zhang, L., Teng, Y., ZHANG, Y., LIU, J., Xu, L., Qu, J., Hou, K., Yang, X., Liu, Y., & Qu, X. (2012) · Apmis · doi:10.1111/j.1600-0463.2011.02864.x · Cited by 17

Advancing Src kinase inhibition: From structural design to therapeutic innovation - A comprehensive review

Su, Y., Zhu, K., Wang, J., Liu, B., Chang, Y., Chang, D., & You, Y. (2025) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2025.117369 · Cited by 20

The Differential Impact of SRC Expression on the Prognosis of Patients with Head and Neck Squamous Cell Carcinoma

Hermida-Prado, F., Granda-Díaz, R., Del-Río-Ibisate, N., Villaronga, M., Allonca, E., Garmendia, I., Montuenga, L., Rodríguez, R., Vallina, A., Álvarez-Marcos, C., et al. (2019) · Cancers · doi:10.3390/cancers11111644 · Cited by 12

N- and s-substituted Pyrazolopyrimidines: A promising new class of potent c-Src kinase inhibitors with prominent antitumor activity

Awaji, A. A., Zaloa, W. A. Z. E., Seleem, M. A., Alswah, M., Elsebaei, M. M., Bayoumi, A. H., El-morsy, A., Alfaifi, M. Y., Shati, A. A., Elbehairi, S. E. I., et al. (2024) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2024.107228 · Cited by 16

SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts

Muramatsu, M., Gao, L., Peresie, J., Balderman, B., Akakura, S., & Gelman, I. H. (2017) · Oncotarget · doi:10.18632/oncotarget.20092 · Cited by 16

Regulation of transforming growth factor β‑mediated epithelial‑mesenchymal transition of lens epithelial cells by c‑Src kinase under high glucose conditions

Han, Z., Wang, F., Wang, F., Liu, Q., & Zhou, J. (2018) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2018.6348 · Cited by 16

Targeted therapies for non-HPV-related head and neck cancer: challenges and opportunities in the context of predictive, preventive, and personalized medicine

Shahoumi, L. A., & Yeudall, W. A. (2019) · The EPMA Journal · doi:10.1007/s13167-019-00177-y · Cited by 17

N-myristoyltransferase in the leukocytic development processes

Kumar, S., Singh, B., Dimmock, J. R., & Sharma, R. K. (2011) · Cell and Tissue Research · doi:10.1007/s00441-011-1202-x · Cited by 17

Cytotoxic activity assessment, QSAR and docking study of novel bis-carboxamide derivatives of 4-pyrones synthesized by Ugi four-component reaction

Shahrisa, A., Esmati, S., Miri, R., Firuzi, O., Edraki, N., & Nejati, M. (2013) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2013.05.049 · Cited by 16

Inhibition of Nonsmall Cell Lung Cancer Cell Migration by Protein Arginine Methyltransferase 1-small Hairpin RNA Through Inhibiting Epithelial-mesenchymal Transition, Extracellular Matrix Degradation, and Src Phosphorylation In Vitro

Zhang, T., Cui, G., Yao, Y., Guo, Y., Wang, Q., Li, X., & Feng, W. (2015) · Chinese Medical Journal · doi:10.4103/0366-6999.156126 · Cited by 16

miR-181a : regulatory roles, cancer-associated signaling pathway disruptions, and therapeutic potential

McIntyre, G., Jackson, Z., Colina, J. A., Sekhar, S. C., & DiFeo, A. V. (2024) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2024.2433687 · Cited by 15

Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles

Aleem, S. U., Georghiou, G. P., Kleiner, R. E., Guja, K. E., Craddock, B. P., Lyczek, A., Chan, A. I., García–Díaz, M., Miller, W. T., Liu, D. R., et al. (2016) · Cell chemical biology · doi:10.1016/j.chembiol.2016.07.017 · Cited by 15

CD151 enrichment in exosomes of luminal androgen receptor breast cancer cell line contributes to cell invasion

Li, D., Lai, W., Wang, Q., Xiang, Z., Nan, X., Yang, X., & Fang, Q. (2021) · Biochimie · doi:10.1016/j.biochi.2021.06.007 · Cited by 15

New FDA oncology small molecule drugs approvals in 2020: Mechanism of action and clinical applications

Nogueira, T. C. M., & Souza, M. V. N. D. (2021) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2021.116340 · Cited by 16

Combined Inhibition of Fyn and c-Src Protects Hippocampal Neurons and Improves Spatial Memory via ROCK after Traumatic Brain Injury

Ye, Z., Izadi, A., Gurkoff, G. G., Rickerl, K., Sharp, F. R., Ander, B. P., Bauer, S. Z., Lui, A., Lyeth, B. G., & Liu, D. (2022) · Journal of Neurotrauma · doi:10.1089/neu.2021.0311 · Cited by 15

1-o-acetylbritannilactone (ABL) inhibits angiogenesis and lung cancer cell growth through regulating VEGF-Src-FAK signaling

He, Z., Zhang, H., Miao, H., Zhi-jun, L., Zhou, J., Yan, X., & Xiujun, C. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.06.126 · Cited by 15

Current Advances in the Development of Anticancer Drugs Targeting Tyrosine Kinases of the Src Family

Schenone, S., Zanoli, S., Brullo, C., Crespan, E., & Maga, G. (2008) · Current Drug Therapy · doi:10.2174/157488508785747862 · Cited by 15

Global Phosphotyrosine Proteomics Identifies PKCδ as a Marker of Responsiveness to Src Inhibition in Colorectal Cancer

McKinley, E. T., Liu, H., McDonald, W. H., Luo, W., Zhao, P., Coffey, R. J., Hanks, S. K., & Manning, H. C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080207 · Cited by 15

Structural basis for the inhibitor recognition of human Lyn kinase domain

Miyano, N., Kinoshita, T., Nakai, R., Kirii, Y., Yokota, K., & Tada, T. (2009) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2009.10.038 · Cited by 15

Antitumor Activity of Src Inhibitor Saracatinib (AZD-0530) in Preclinical Models of Biliary Tract Carcinomas

Cavalloni, G., Neia, C. P., Sarotto, I., Gammaitoni, L., Migliardi, G., Soster, M., Marchiò, S., Aglietta, M., & Leone, F. (2012) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-11-1020 · Cited by 15

CEP55 Positively Affects Tumorigenesis of Esophageal Squamous Cell Carcinoma and Is Correlated with Poor Prognosis

Yan, S., Liu, L., Gu, W.-Y., Huang, L., Yang, Y., Huang, Y., & Luo, R. (2021) · Journal of Oncology · doi:10.1155/2021/8890715 · Cited by 15

HGF-induced capillary morphogenesis of endothelial cells is regulated by Src.

Kanda, S., Kanetake, H., & Miyata, Y. (2006) · Biochemical and Biophysical Research Communications - BBRC · doi:10.1016/j.bbrc.2006.03.183 · Cited by 19

Lidocaine suppresses the malignant behavior of gastric cancer cells via the c‑Met/c‑Src pathway

Zeng, W., Xing, Z., Tan, M., Wu, Y., & Zhang, C. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.9868 · Cited by 14

The potent role of Src kinase-regulating glucose metabolism in cancer.

Shao, W., Liu, L., Zheng, F., Ma, Y., & Zhang, J. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115333 · Cited by 15

Dasatinib inhibits mammary tumour development in a genetically engineered mouse model

Karim, S., Creedon, H., Patel, H., Carragher, N., Morton, J., Muller, W., Evans, T. R., Gusterson, B., Sansom, O., & Brunton, V. (2013) · Journal of Pathology · doi:10.1002/path.4202 · Cited by 18

Rhodomycin A, a novel Src-targeted compound, can suppress lung cancer cell progression via modulating Src-related pathways

Lai, Y., Chen, M.-H., Lin, S.-Y., Lin, S.-Y., Wong, Y.-H., Yu, S., Chen, H., Yang, C.-H., Chang, G., & Chen, J. J. W. (2015) · Oncotarget · doi:10.18632/oncotarget.4761 · Cited by 14

4-Hydroxynonenal activates Src through a non-canonical pathway that involves EGFR/PTP1B

Zhang, H., & Forman, H. J. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.08.025 · Cited by 15

c‐Src promotes tumor progression through downregulation of microRNA‐129‐1‐3p

Okuzaki, D., Yamauchi, T., Mitani, F., Miyata, M., Ninomiya, Y., Watanabe, R., Akamatsu, H., & Oneyama, C. (2019) · Cancer Science · doi:10.1111/cas.14269 · Cited by 13

Myeloid-derived suppressor cells in head and neck squamous cell carcinoma

He, J.-Y., Huo, F., Tang, H., Liu, B., & Bu, L. (2023) · International review of cytology · doi:10.1016/bs.ircmb.2022.11.002 · Cited by 14

A negative feedback loop underlies the Warburg effect

Jaiswal, A., & Singh, R. (2024) · npj Systems Biology and Applications · doi:10.1038/s41540-024-00377-x · Cited by 13

Protein Kinases and Associated Pathways in Pluripotent State and Lineage Differentiation

Shoni, M., Lui, K. O., Vavvas, D. G., Muto, M. G., Berkowitz, R. S., Vlahos, N., & Ng, S.-W. (2014) · Current Stem Cell Research & Therapy · doi:10.2174/1574888x09666140616130217 · Cited by 13

Advances in Regulating Tumorigenicity and Metastasis of Cancer Through TrkB Signaling

Zou, W., Hu, X., & Jiang, L. (2020) · Current Cancer Drug Targets · doi:10.2174/1568009620999200730183631 · Cited by 14

Role of Src Family Kinases in Prolactin Signaling

Martín-Pérez, J., García-Martínez, J. M., Sánchez-Bailón, M. P., Mayoral-Varo, V., & Calcabrini, A. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-12114-7_7 · Cited by 14

Development of novel benzotriazines for drug discovery

Palanki, M. S. S., Cao, J., Chow, C. P., Dneprovskaia, E., Mak, C. C., McPherson, A. K., Pathak, V. P., Renick, J., Söll, R., Zeng, B., et al. (2008) · Expert Opinion on Drug Discovery · doi:10.1517/17460440802580536 · Cited by 13

Src regulates the activity of the mammalian formin protein FHOD1

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Bosutinib: A Potent Second-Generation Tyrosine Kinase Inhibitor

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