Src family kinases in tumor progression and metastasis

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A SARCOMA OF THE FOWL TRANSMISSIBLE BY AN AGENT SEPARABLE FROM THE TUMOR CELLS

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Csk-homologous kinase (Chk/Matk): a molecular policeman suppressing cancer formation and progression

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Src transformation of colonic epithelial cells: Enhanced anchorage‐independent growth in an Apc+/min background

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Silencing of Src by siRNA inhibits laryngeal carcinoma growth through the Src/PI-3 K/Akt pathway in vitro and in vivo

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Targeted Therapy in Colorectal Cancer

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Cucurbitacin B in cancer: A comprehensive review of its targets and molecular mechanisms

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Multi-omics approaches including single-cell analysis and machine learning were used to identify the roles of telomere-related genes in esophageal squamous cell carcinoma

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The effect of tyrosine kinase inhibitors used in the treatment of chronic myeloid leukemia on the cardiovascular system

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Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma

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Molecular Targeted Therapies in Head and Neck Cancer

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Distinct and opposite roles for SH2 and SH3 domains of v-src in embryo survival and hemangiosarcoma formation

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Simultaneous suppression of Src and signal transducer and activator of transcription 3 inhibits the growth of epithelial ovarian cancer cells

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Cooperative Interactions Between c-Src, Estrogen Receptors and Receptor Tyrosine Kinases in Breast Cancer

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Low Molecular Weight Components in Aqueous Echinacea Purpurea Leaf Extract Inhibit Melanoma Cell Growth

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Inhibitors of Tau-Phosphorylating Kinases

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The Prognostic Value of Tyrosine Kinase SRC Expression in Locally Advanced Rectal Cancer

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V-Src delocalizes Aurora B by suppressing Aurora B kinase activity during monopolar cytokinesis.

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Therapeutic strategy using novel RET/YES1 dual-target inhibitor in lung cancer

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Cancer-targeted therapies and radiopharmaceuticals

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Plakophilin-2 induced EGFR phosphorylation: a focus on the intracellular activators of EGFR

Arimoto, K., Weng, S., & Zhang, D. (2015) · Receptors & Clinical Investigation · doi:10.14800/rci.485 · Cited by 2

Endocrine resistance and breast cancer invasion

Hiscox, S., Gee, J. M. W., & Nicholson, R. I. (2007) · Cancer metastasis · doi:10.1007/978-1-4020-5867-7_7 · Cited by 2

SMART Drug Design: Novel Phosphopeptide and ATP Mimetic-Based Small Molecule Inhibitors of the Oncogenic Protein Kinase pp60src (Src)

Sawyer, T. K., Bohacek, R. S., Shakespeare, W. C., Metcalf, C. A., Wang, Y., Sundaramoorthi, R., Keenan, T. P., Narula, S. S., & Dalgarno, D. C. (2005) · Springer eBooks · doi:10.1007/0-387-24532-4_11 · Cited by 2

Comparative Activity and Specificity of Antisense Oligodeoxynucleotides and Small Interfering RNA in an in vitro Ewing Sarcoma Model

Villemeur, M., Tamaddon, A. M., Bertrand, J., & Malvy, C. (2009) · The Open Nanomedicine Journal · doi:10.2174/1875933500902010036 · Cited by 3

Methylenedioxyanilino-quinazolines and -cyanoquinolines as inhibitors of MEK and/or Src

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Investigation of phytoconstituents interactions with human Src kinase in a bid to improve cholangiocarcinoma chemotherapy: An in-silico approach

Rolta, R., Salaria, D., Fadare, O. A., Kaur, G., Fadare, R. Y., Prakash, A., Kaman, L., & Medhi, B. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152733 · Cited by 1

Recent advances in Pyrazolo[3,4-d]pyrimidine-based dual inhibitors in the treatment of cancers

Jiang, H., Li, N., Qin, R., Lin, S., Wang, X., Li, C., Shen, J., Chen, Y., Liu, J., & Ding, S. (2025) · Molecular Diversity · doi:10.1007/s11030-025-11379-0 · Cited by 1

Environmentally relevant levels of BDE-209 induces proteomic and phosphoproteomic reprogramming in murine melanoma cells

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Precision targeting of SRC signaling in glioblastoma: Mechanistic insights and bilosome nanotechnology

Madalageri, M., Sadashivanavar, V., Kinnal, R., Atchou, K., & Pai, K. S. R. (2026) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2026.154083 · Cited by 1

Inhibition of the Src Oncogene: Therapeutic Potential in Ovarian Carcinoma

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Genetically Modified Bacteria as Targeted Agent for Cancer

Jin, S., Whang, Y. M., & Chang, I. H. (2016) · Journal of Urologic Oncology · doi:10.22465/kjuo.2016.14.2.54 · Cited by 1

Mucosal Repair and Restitution

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Genetic Susceptibility Markers of Gastrointestinal Cancer

Kumar, M., & Pola, S. (2020) · Diagnostics and therapeutic advances in GI malignancies · doi:10.1007/978-981-15-4431-6_7 · Cited by 1

Nano drug delivery strategies for the treatment and diagnosis of oral and throat cancers

Perdomo, S. J., Fonseca-Benítez, A. V., Cardona-Mendoza, A., Romero‐Sánchez, C., & Párraga, J. E. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819793-6.00004-7 · Cited by 1

Molecular Processes Involved in Pancreatic Cancer and Therapeutics

Makar, S., Ghosh, A., divya, D. D., Shivhare, S., Kumar, A., & Singh, S. K. (2020) · Current Chemical Biology · doi:10.2174/2212796814999201008130819 · Cited by 1

Phosphorylation-mediated interaction between human E26 transcription factor 1 and specific protein 1 is required for tumor cell migration

Wen, X.-H., Sun, X., Ou, Z., Jiang, J., Chen, Q., He, X., Hu, Z., Qiao, H., Zhou, K., Li, X., et al. (2022) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2022148 · Cited by 1

The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells

Steiro, I. J., Vandsemb, E. N., Elsaadi, S., Misund, K., Sponaas, A., Børset, M., Abdollahi, P., & Slørdahl, T. S. (2022) · Oncotarget · doi:10.18632/oncotarget.28300 · Cited by 1

Synthetic Migrastatic: A New Class of Anticancer Drug

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Integrated bioinformatics and network pharmacology to explore the therapeutic target and molecular mechanisms of Taxus chinensis against non-small cell lung cancer

Zhang, S., Wang, J., & Zhang, H. (2023) · Medicine · doi:10.1097/md.0000000000035826 · Cited by 1

REGIONAL ANAESTHESIA AND ACUTE PAIN

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CIP4 and Src in Promoting the Migration and Invasion of Breast Cancers

Pichot, C. S. (2010) · Digital Commons-TMC (Texas Medical Center) · Cited by 1

Adverse Features of Acquired Antihormone Resistance and Their Targeting

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Pharmacogenomics of Dasatinib (Sprycel™)

Huang, F., & Clark, E. A. (2009) · Wiley eBooks · doi:10.1002/9780470524961.ch15 · Cited by 1

Oct3 and Sox2 Expression in Mammary Carcinoma Cells

Soignier, Y. (2010) · eScholarship (California Digital Library) · Cited by 1

Cross talk between ERα and Src signaling and its relevance to ER status and hormone responsiveness

Sun, J., Zhou, W., Nawaz, Z., & Slingerland, J. (2012) · Springer eBooks · doi:10.1007/978-1-4614-1764-4_4

Clinical Development of Src Family Kinase Inhibitors in Malignant Melanoma

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YES, a novel therapeutic target in hepatocellular carcinoma

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EGFRvIII Expression and Signaling in head and neck squamous cell carcinoma

Wheeler, S. E. (2012) · D-Scholarship@Pitt (University of Pittsburgh) · Cited by 1

Slap restricts oncogenic Src-family kinase signaling to maintain colonic epithelial homeostasisPreprint

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Knochenmetastasen

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Src Family Tyrosine Kinase Signaling in Mouse and Human Embryonic Stem Cells

Zhang, X. (2013) · D-Scholarship@Pitt (University of Pittsburgh)

Active transport and CNS delivery of novel tyrosine kinase inhibitors.

Chen, Y. (2009) · University of Minnesota Digital Conservancy (University of Minnesota)

Investigating the SRC kinase HCK functions in Chronic Myelogenous Leukemia using chemical genetics methods.

Dumitrescu, T. P. (2009) · D-Scholarship@Pitt (University of Pittsburgh)

Identification of Novel c-Yes Kinase Inhibitors

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Factors relacionats amb el manteniment de la inflamació i l'oclusió vascular. Implicacions en l'evolució dels pacients amb arteritis de cèl·lules gegants.

García, E. L. (2008) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

The Role of c-Src Activation in Prostate Tumor Progression

Gallick, G. E. (2004) · doi:10.21236/ada429162

Regulation of Breast Cancer Stem Cell by Tissue Rigidity

Engler, A. J., Yang, J., Wei, S. C., Fattet, L., & Ondeck, M. G. (2014) · Defense Technical Information Center (DTIC) · doi:10.21236/ada609393

SRC (v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian))

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c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells trough activation of phosphatidyl inositol-3 kinase and p38 MAPK

Summy, J. M., Trevino, J. G., Baker, C. H., & Gallick, G. E. (2006) · Suizo · doi:10.2958/suizo.21.381

The Role Of IL-8-Mediated Src Family Kinase Activation In Tumor-Tumor And Tumor-Stromal Interactions In Metastasis Of Prostate Cancer

Thorpe, L. (2013) · Digital Commons-TMC (Texas Medical Center)

Quantitative in vitro characterization of transformed cell lines as a model for metastatic dissemination

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Regulació de la producció de gelatinases (MMP2 i MMP9) pels limfòcits. Implicació en malalties inflamatòries i

Blasco, M. S., & Cid, C. (2006)

Targeting the Tumor Microenvironment With Src

Chung, A. S., & Ferrara, N. (2010)

PEPTÍDEO C16, DERIVADO DA LAMININA, REGULA INVASÃO, DINÂMICA DE FORMAÇÃO E ATIVIDADE DE INVADOPÓDIOS EM LINHAGENS CELULARES DE CARCINOMA EPIDERMÓIDE E FIBROSSARCOMA

Paulo, S. (2014)

The role and mechanism of action of BRK in breast cancer progression

Miah, S. (2015) · University Library - University of Saskatchewan (University of Saskatchewan)

Acción del hexaclorobenceno en la migración, invasión y metástasis en modelos experimentales de cáncer de mama

Pontillo, C. A. (2012) · Repositorio Digital Institucional de la Universidad de Buenos Aires (Universidad de Buenos Aires)

Mechanism of Hic-5/ARA55 action, a novel stromal-specific nuclear receptor coactivator

Heitzer, M. D. (2005) · D-Scholarship@Pitt (University of Pittsburgh)

Dynamic Src Tyrosine Kinase Signaling Directs Invadopodia Formation and Function in Head and Neck Cancer: Novel Insights into the Original Oncogene

Kelley, L. C. (2010) · The Research Repository @ WVU (West Virginia University) · doi:10.33915/etd.3258

Convergance of Cytoskeletal Signaling at p21-Activated Kinases

Gururaj, A. E., & Kumar, R. (2008) · Springer eBooks · doi:10.1007/978-1-4020-8341-9_5

Cardiotoxin III suppresses the invasiveness of MDA-MB-231 cells by targeting proto-oncogene tyrosine-protein kinase Src and reversing mesenchymal-to-epithelial transition

Tsai, P., Lin, Y., Fu, Y., Chang, L., & Lin, S. (2016) · Toxicological & Environmental Chemistry Reviews · doi:10.1080/02772248.2015.1137099

Use of genetically engineered mouse models in preclinical drug development

Creedon, H. (2015) · ERA

STAT3 and Src Signaling in Melanoma

Kujawski, M., Cherryholmes, G. A., Priceman, S. J., & Yu, H. (2011) · Springer eBooks · doi:10.1007/978-1-61779-407-0_7

Abelson Kinase Based Regulation of Tumor Cell Invasion in HNSCC

Hayes, K. E. (2013) · The Research Repository @ WVU (West Virginia University) · doi:10.33915/etd.472

A BALANCING ACT BETWEEN THE 'SRC-STAT3' AND 'P53- CALDESMON' PATHWAYS DICTATES THE OUTCOME OF SRC- INDUCED INVASIVE PHENOTYPES

Mooney, P. (2010)

Identification of SRC, LCK, ABL, JAK1 genes exrression in lymphohemopoietic complex cells on fetal material application

Goltsev, А. М., Луценко, О. Д., Yampolska, K., Ostankov, M. V., & Бондарович, М. О. (2016) · ScienceRise Biological Science · doi:10.15587/2519-8025.2016.72757

Study Of The Egfr, Src And Stat3 Pathway In Pancreatic Cancer

Jaganathan, S. (2010) · Journal of International Crisis and Risk Communication Research

Phospho-proteomic Analysis of Neuroblastoma Tumor Initiating Cell Signaling Pathways: Identification of Src Family and B Cell Receptor Signaling as Novel Drug Targets

Vojvodic, M. (2010) · TSpace (University of Toronto)

Fyn-Mediated Regulation of Protein Kinase A

Barritt, S. (2017) · ScholarWorks -A service of University of Vermont Libraries (University of Vermont)

The Role of Cadherin-11 and gp130 in Transformation by Activated Src

D'Abreo, C. (2011) · QSpace (Queen's University Library)

Interaction of BIR2/3 of XIAP with E2F1/Sp1 Activates MMP2 and Bladder Cancer Invasion by Inhibiting Src TranslationPreprint

Xu, J., Jin, H., Li, J., Zhu, J., Hua, X., Tian, Z., Huang, M., Yang, R., Huang, H., & Huang, C. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/309765

Post-translational myristoylation during cell death

Martin, D. D. O. (2011) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r36x2s

FRK cancer-related mutations: Effect on enzymatic activity and cellular processes

MacAusland-Berg, J. (2019) · HARVEST (University of Saskatchewan)

The adaptor protein APPL1 regulates cell migration and adhesion dynamics

Broussard, J. A. (2012)

Investigations into the Interaction between Src Kinase and Wnt Signaling

Tang, P. L. (2009) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/14854

LYN kinase and estrogen receptor ERα: involvement in carcinogenesis and potential therapeutic target for tumors

Тихонова, В. В., Finashutina, Y. P., & Кесаева, Л. А. (2021) · Advances in molecular oncology · doi:10.17650/2313-805x-2021-8-3-44-59

Head and Neck Cancer Metastasis

Laskar, S. G., Agarwal, J. P., Mallick, I., & Dinshaw, K. A. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511976117.030

Synthetic Migrastatic: A New Class of Anticancer Drug

Gayan, S., Doshi, S., & Dey, T. (2022) · Handbook of Oxidative Stress in Cancer: Therapeutic Aspects · doi:10.1007/978-981-16-1247-3_266-1

c-Src Family of Tyrosine Kinases

Sen, B., & Johnson, F. M. (2012) · Springer eBooks · doi:10.1007/978-1-4419-0461-4_54

Modulação das vias de sinalização de sobrevivência, ciclo celular, resistência e potencial metastático pela etoxzolamida na linhagem celular de adenocarcinoma ductal de pâncreas humano (PANC-1)

Limia, C. E. G. (2013) · doi:10.47749/t/unicamp.2013.913992

Analysis of differential gene expression between right-sided and left-sided colon cancer by bioinformatics analysisPreprint

Chi, Q., Chen, S., & Li, S. (2020) · doi:10.21203/rs.3.rs-23894/v1

c-Src Family of Tyrosine Kinases

Sen, B., & Johnson, F. M. (2017) · Springer eBooks · doi:10.1007/978-3-319-67199-4_54

Evaluation of the Efficacy of Saracatinib-Loaded Nanoparticles in Lymphatic Metastases of HNSCC with the Aid of Bioluminescence Imaging

Lang, L., & Teng, Y. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2473-9_2

A negative feedback loop underlies the Warburg effectPreprint

Singh, R., & Jaiswal, A. (2023) · Research Square · doi:10.21203/rs.3.rs-3465493/v1

Exploring targets and related mechanisms of Scutellaria baicalensis for treating non-small cell lung cancer based on network pharmacology

Luo, Y., Li, T., Long, R., Guo, Q., Wei, L., & Wang, X. (2024) · Pharmacological Research - Modern Chinese Medicine · doi:10.1016/j.prmcm.2024.100381

Integrated analysis to find MicroRNAs and Genes Associated with Metastasis and Cisplatin and 5-Fluorouracil Resistance Gastric CancerPreprint

Iranmehr, Z., Yasavoli‐Sharahi, H., Ghaemi, F., Miri, S. R., & Ebrahimi, M. (2024) · Research Square · doi:10.21203/rs.3.rs-5416147/v1

Irradiation of prostate cancer alters circulating small extracellular vesicle functions

Sayeed, A., Garcia, V., Verrillo, C. E., DeRita, R. M., Hossain, M. N., Krishn, S. R., Sey, S., Shields, C. D., Altieri, A. D., Liu, Q., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-03329-5

Current Concepts in Oral Cancer Metastasis and the Possible Role of Desmoglein 3 in Lymph Node Metastasis

Yellarthi, P. K., Muthukrishnan, A., Vaishali, M., Mehta, D. N., & Rao, G. R. R. (2025) · Advances in Human Biology · doi:10.4103/aihb.aihb_147_25

Imipramine Inhibits Osteosarcoma Invasion via Src Inactivation and Caspase‐Dependent Apoptosis

Liu, Y., Fang, C., Hsu, L., Hsu, F., & Hu, M. (2025) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70761

Nonreceptor Tyrosine Kinases and Their Roles in Cancer

Wiener, J. R., & Gallick, G. E. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1216-8_4

Structural and functional characterization of the intrinsically disordered Unique domain of c-Src

Maffei, M. (2014) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Role of c-Src Activation on Prostate Cancer Lymph Node Metastases

Park, S. I. (2008) · doi:10.21236/ada493721

The Role of Src in Solid Tumors

Wheeler, D. L., Iida, M., & Dunn, E. F. (2009) · The Oncologist · doi:10.1634/theoncologist.2009-0009 · Cited by 346

Regulation of Src Family Kinases in Human Cancers

Sen, B., & Johnson, F. M. (2011) · Journal of Signal Transduction · doi:10.1155/2011/865819 · Cited by 235

doi:10.1155/2011/865819 Review Article Regulation of Src Family Kinases in Human Cancers

Sen, B., & Johnson, F. M. (2011)

Proteínas cinasas de la familia SRC en el desarrollo del cáncer

Cruz, I. S. (2012)

Src Family Nonreceptor Tyrosine Kinases as Molecular Targets for Cancer Therapy

Johnson, F. M., & Gallick, G. E. (2007) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152007784111278 · Cited by 97