Nasal obstruction as a risk factor for sleep apnoea syndrome
Open accessAbstract
Nasal obstruction has frequently been mentioned as a possible risk factor in obstructive sleep apnoea syndrome (OSAS). Over a 2-yr period, 541 unselected consecutive snorers referred for suspected breathing disorders during sleep were included to undergo posterior rhinomanometry. In addition cephalometric landmarks and body mass index (BMI) were obtained. Polysomnography was used to determine the number of abnormal respiratory events that occurred during sleep. OSAS was defined as 15 episodes, or more, of apnoea or hypopnoea per hour of sleep (AHI). Of the 541 consecutive snorers 528 underwent nasal resistance measurement by posterior rhinomanometry (failure rate: 2.4%). Patients with OSAS (259 patients) had higher nasal resistance than patients without OSAS (2.6+/-1.6 hPa x L x s(-1) versus 2.2+/-1.0 hPa x L x s(-1), respectively, p<0.005). A stepwise multiple regression analysis showed that BMI, male sex, nasal resistance, and cephalometric parameters were contributing factors to the AHI. The r2-value of the multiple regression analysis was 0.183. Nasal resistance contributed 2.3% of the variance (p<0.0001), whereas mandibular plane-hyoid distance, BMI, male sex and age contributed 6.2%, 4.6%, 3% and 1.3% of the variance, respectively. To conclude, daytime nasal obstruction is an independent risk factor for OSAS.
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A study of 541 snorers who underwent posterior rhinomanometry concluded that nasal obstruction is an independent risk factor for OSA.
“A study of 541 snorers who underwent posterior rhinomanometry concluded that nasal obstruction is an independent risk factor for OSA.297”
From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [297]
The Abstract says 541 snorers were included to undergo posterior rhinomanometry, but only 528 completed the measurement. It explicitly concludes that daytime nasal obstruction is an independent risk factor for obstructive sleep apnoea syndrome; the claim overstates the number who underwent the test. (LLM, conf=0.90)
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- Authors
- Lofaso, F., Coste, A., d′ortho, M. P., Zerah-Lancner, F., Delclaux, C., Goldenberg, F., & Harf, A.
- Affiliations
- Hôpital Raymond-Poincaré (FR)
- Inserm (FR)
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2000-10
- Volume
- 16
- Issue
- 4
- Pages
- 639
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2126646029
- Semantic Scholar
- ecf097577294b859dda35be1b2cd8d3b1228f5cf
- Cited by
- 247
- References
- 26
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 4 · 2023: 15 · 2022: 12 · 2021: 11 · 2020: 10 · 2019: 13 · 2018: 11 · 2017: 9 · 2016: 15 · 2015: 6 · 2014: 17 · 2013: 10 · 2012: 6
- FWCI
- 3.41
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Respiratory Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- nasal obstruction, obstructive sleep apnea, nasal resistance, risk factors, snoring, body mass index, cephalometric landmarks, apnea-hypopnea index, male sex
- MeSH terms
- Airway Resistance, Cephalometry, Female, Humans, Male, Manometry, Middle Aged, Prospective Studies, Regression Analysis, Risk Factors, Sleep Apnea Syndromes, Nasal Obstruction, Body Mass Index, Polysomnography
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