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Cited by 145Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and AccessMental Health Research Topics

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Clinical significance and comorbidity of subthreshold depression and anxiety in the community

Preisig, M., Merikangas, K. R., Angst, J.·2001·Acta Psychiatrica Scandinavica
DOI 10.1034/j.1600-0447.2001.00284.x
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Abstract

OBJECTIVE: This report examines: 1) the magnitude of co-occurrence of threshold and subthreshold-level depression and anxiety in the community, and 2) the relationship between comorbidity and the diagnostic level of depression and anxiety and their clinical correlates. METHOD: A community sample of 591 subjects was interviewed prospectively five times across 15 years from the ages of 20-35. The diagnostic interview allowed the assignment of diagnoses according to DSM-III criteria and operational definitions of subthreshold syndromes. RESULTS: 1) Comorbidity between depression and anxiety was more frequent when one syndrome reached threshold level; 2) comorbidity at both the threshold and subthreshold diagnostic levels was associated with symptom severity, disability and treatment, whereas the diagnostic level was associated with disability and suicidal attempts. CONCLUSION: The systematic association between comorbidity across diagnostic threshold levels of anxiety and depression with clinical correlates suggests the importance of a more dimensional approach to their classification.

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Crossref · 10.1034/j.1600-0447.2001.00284.x

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Metadata

Authors
Preisig, M., Merikangas, K. R., & Angst, J.
Affiliations
  • University of Lausanne (CH)
  • Yale University (US)
  • Psychiatrische Universitätsklinik Zürich (CH)
ORCID
Venue
Acta Psychiatrica Scandinavica
Publisher
Wiley
Published
2001-08
Volume
104
Issue
2
Pages
96-103
ISSN
  • 0001-690X (ISSN-L)
  • 1600-0447
DOI
10.1034/j.1600-0447.2001.00284.x
OpenAlex
W2094870250
Cited by
145
References
33
Citations by year
2026: 2 · 2025: 2 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 8 · 2019: 8 · 2018: 6 · 2017: 5 · 2016: 7 · 2015: 8 · 2014: 8 · 2013: 4 · 2012: 6
FWCI
8.00
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 817 d)
Locations
  • Acta Psychiatrica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
  • IRIS (submittedVersion)
  • SERVAL (Université de Lausanne) (submittedVersion)
Funders
  • Systematics Association
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
  • U.S. Public Health Service (KO2-0499)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
Keywords
subthreshold depression, subthreshold anxiety, comorbid depression and anxiety, dimensional classification, symptom severity, disability, suicide attempts, community mental health, young adults
MeSH terms
Adult, Anxiety Disorders, Depressive Disorder, Diagnosis, Differential, Female, Humans, Longitudinal Studies, Male, Comorbidity, Incidence

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