The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Clinical significance and comorbidity of subthreshold depression and anxiety in the community
Abstract
OBJECTIVE: This report examines: 1) the magnitude of co-occurrence of threshold and subthreshold-level depression and anxiety in the community, and 2) the relationship between comorbidity and the diagnostic level of depression and anxiety and their clinical correlates. METHOD: A community sample of 591 subjects was interviewed prospectively five times across 15 years from the ages of 20-35. The diagnostic interview allowed the assignment of diagnoses according to DSM-III criteria and operational definitions of subthreshold syndromes. RESULTS: 1) Comorbidity between depression and anxiety was more frequent when one syndrome reached threshold level; 2) comorbidity at both the threshold and subthreshold diagnostic levels was associated with symptom severity, disability and treatment, whereas the diagnostic level was associated with disability and suicidal attempts. CONCLUSION: The systematic association between comorbidity across diagnostic threshold levels of anxiety and depression with clinical correlates suggests the importance of a more dimensional approach to their classification.
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“Our findings demonstrate a notable portion of fathers experience subthreshold levels of internalizing problems, which might be overlooked despite the fact that subthreshold symptoms may be associated with maladaptive functioning [92].”
From Trajectories of Maternal and Paternal Internalizing Symptoms from Pregnancy to 2 Years Postpartum: Identifying Modifiable Risk and Protective Factors (2024) · cites this paper as [92]
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Cites
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Time-related predictors of suicide in major affective disorder
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Kessler, R. C., Zhao, S., Blazer, D. G., & Swartz, M. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00056-6 · Cited by 790
Major Depression and Generalized Anxiety Disorder: Same Genes, (Partly) Different Environments?
Kendler, K. S. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820090044008 · Cited by 773
Sartorius, N., Üstün, T. B., Lecrubier, Y., & Wittchen, H.-U. (1996) · British Journal of Psychiatry · doi:10.1192/s0007125000298395 · Cited by 541 · cited 2×
“Studies of primary care settings such as the World Health Organization study (9) have also revealed that a substantial proportion of subjects with disabling depressive symptoms fail to meet the diagnostic criteria for major depression.”
BackgroundLifetime and six-month prevalence of mental disorders in the Munich follow-up study
Wïttchen, H., Essau, C. A., Zerssen, D. V., Krieg, J.-C., & Zaudig, M. (1992) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf02190261 · Cited by 439
The Cross-national Epidemiology of Panic Disorder
Weissman, M. M. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830160021003 · Cited by 436
Boundaries of Major Depression: An Evaluation of DSM-IV Criteria
Kendler, K. S., & Gardner, C. O. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.2.172 · Cited by 430
The continuity of depression in clinical and nonclinical samples.
Flett, G. L., Vredenburg, K., & Krames, L. (1997) · Psychological Bulletin · doi:10.1037/0033-2909.121.3.395 · Cited by 374
Kessler, R. C., Stang, P., Wittchen, H., Üstün, T. B., Roy-Burne, P. P., & Walters, E. (1998) · The British journal of psychiatry : the journal of mental science · doi:10.1001/archpsyc.55.9.801 · Cited by 357
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Kessler, R. C., & Üstün, T. B. (2004) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.168 · Cited by 4,771
Chronic Insomnia as a Risk Factor for Developing Anxiety and Depression
Neckelmann, D., Mykletun, A., & Dahl, A. A. (2007) · Sleep · doi:10.1093/sleep/30.7.873 · Cited by 665
Cuijpers, P., & Smit, F. (2004) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2004.00301.x · Cited by 595
Longitudinal Trajectories of Depression and Anxiety in a Prospective Community Study
Merikangas, K. R., Zhang, H., Avenevoli, S., Acharyya, S., Neuenschwander, M., & Angst, J. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.9.993 · Cited by 434
Self-citationMild Disorders Should Not Be Eliminated From the DSM-V
Kessler, R. C., Merikangas, K. R., Berglund, P., Eaton, W. W., Koretz, D. S., & Walters, E. E. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.11.1117 · Cited by 348
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Metadata
- Authors
- Preisig, M., Merikangas, K. R., & Angst, J.
- Affiliations
- University of Lausanne (CH)
- Yale University (US)
- Psychiatrische Universitätsklinik Zürich (CH)
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 2001-08
- Volume
- 104
- Issue
- 2
- Pages
- 96-103
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- OpenAlex
- W2094870250
- Cited by
- 145
- References
- 33
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 8 · 2019: 8 · 2018: 6 · 2017: 5 · 2016: 7 · 2015: 8 · 2014: 8 · 2013: 4 · 2012: 6
- FWCI
- 8.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Psychiatrica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- IRIS (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Funders
- Systematics Association
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- U.S. Public Health Service (KO2-0499)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- subthreshold depression, subthreshold anxiety, comorbid depression and anxiety, dimensional classification, symptom severity, disability, suicide attempts, community mental health, young adults
- MeSH terms
- Adult, Anxiety Disorders, Depressive Disorder, Diagnosis, Differential, Female, Humans, Longitudinal Studies, Male, Comorbidity, Incidence
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