Negative symptoms in first episode non‐affective psychosis

Negative v Positive Schizophrenia

Andreasen, N. C. (1982) · Archives of General Psychiatry · doi:10.1001/archpsyc.1982.04290070025006 · Cited by 2,008 · see citing works

Molecular pathology of schizophrenia: more than one disease process?

Crow, T. J. (1980) · BMJ · doi:10.1136/bmj.280.6207.66 · Cited by 1,863 · see citing works

The Symptoms of Chronic Schizophrenia

Liddle, P. F. (1987) · The British Journal of Psychiatry · doi:10.1192/bjp.151.2.145 · Cited by 1,432 · see citing works

Deficit and nondeficit forms of schizophrenia: the concept

Carpenter, W. T., Heinrichs, D. W., & Wagman, A. M. I. (1988) · American Journal of Psychiatry · doi:10.1176/ajp.145.5.578 · Cited by 1,329 · see citing works

A depression rating scale for schizophrenics

Addington, D. E., Addington, J., & Schıssel, B. (1990) · Schizophrenia Research · doi:10.1016/0920-9964(90)90005-r · Cited by 1,270 · see citing works

Measurement of Premorbid Adjustment in Chronic Schizophrenia

Cannon-Spoor, H. E., Potkin, S. G., & Wyatt, R. J. (1982) · Schizophrenia Bulletin · doi:10.1093/schbul/8.3.470 · Cited by 1,197 · see citing works

The Two-syndrome Concept: Origins and Current Status

Crow, T. J. (1985) · Schizophrenia Bulletin · doi:10.1093/schbul/11.3.471 · Cited by 842 · see citing works

The schedule for the deficit syndrome: An instrument for research in schizophrenia

Kirkpatrick, B. R., Buchanan, R. W., McKenny, P. D., Alphs, L. D., & Carpenter, W. T. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90153-4 · Cited by 802 · see citing works

IRAOS: an instrument for the assessment of onset and early course of schizophrenia

Häfner, H., Riecher‐Rössler, A., Hambrecht, M., Maurer, K., Meissner, S., Schmidtke, A., Fätkenheuer, B., Löffler, W., & der Heiden, W. A. (1992) · Schizophrenia Research · doi:10.1016/0920-9964(92)90004-o · Cited by 562 · see citing works

Schizophrenic syndromes, cognitive performance and neurological dysfunction

Liddle, P. F. (1987) · Psychological Medicine · doi:10.1017/s0033291700012976 · Cited by 552 · see citing works

Schizophrenic Syndromes and Frontal Lobe Performance

Liddle, P. F., & Morris, D. L. (1991) · The British Journal of Psychiatry · doi:10.1192/bjp.158.3.340 · Cited by 507 · see citing works

Depression, negative symptoms, social stagnation and social decline in the early course of schizophrenia

Häfner, H., Löffler, W., Maurer, K., Hambrecht, M., & der Heiden, W. A. (1999) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1999.tb10831.x · Cited by 430 · see citing works

The Distinction of Positive and Negative Symptoms

Arndt, S. V., Alliger, R. J., & Andreasen, N. C. (1991) · The British Journal of Psychiatry · doi:10.1192/bjp.158.3.317 · Cited by 408 · see citing works

Quality of life in schizophrenia: relationship to sociodemographic factors, symptomatology and tardive dyskinesia

Browne, S., Roe, M., Lane, A., Gervin, M., Morris, M. J., Kinsella, A., Larkin, C., & O’Callaghan, E. (1996) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1996.tb09835.x · Cited by 332 · see citing works

Positive vs. Negative Schizophrenia: A Critical Evaluation

Andreasen, N. C. (1985) · Schizophrenia Bulletin · doi:10.1093/schbul/11.3.380 · Cited by 331 · see citing works

First-episode Schizophrenia: I. Early Course Parameters

Larsen, T. K., McGlashan, T. H., & Moe, L. C. (1996) · Schizophrenia Bulletin · doi:10.1093/schbul/22.2.241 · Cited by 322 · see citing works

Two-Year Outcome in First-Episode Schizophrenia: Predictive Value of Symptoms for Quality of Life

Ho, B., Nopoulos, P., Flaum, M. A., Arndt, S. V., & Andreasen, N. C. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.9.1196 · Cited by 312 · see citing works

Negative symptoms: a path analytic approach to a double-blind, placebo- and haloperidol-controlled clinical trial with olanzapine

Tollefson, G. D., & Sanger, T. M. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.4.466 · Cited by 306 · see citing works

The Varied Outcomes of Schizophrenia

Davidson, L., & McGlashan, T. H. (1997) · The Canadian Journal of Psychiatry · doi:10.1177/070674379704200105 · Cited by 305 · see citing works

Antecedents, symptom progression, and long-term outcome of the deficit syndrome in schizophrenia

Fenton, W. S., & McGlashan, T. H. (1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.3.351 · Cited by 260 · see citing works

One year outcome in first episode psychosis: influence of DUP and other predictors

MALLA, A. K. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00254-7 · Cited by 234 · see citing works

Prevalence and clinical correlates of extrapyramidal signs and spontaneous dyskinesia in never-medicated schizophrenic patients

Chatterjee, A., Chakos, M., Koreen, A., Geisler, S., Sheitman, B., Woerner, M. G., Kane, J. M., Alvir, J. M., & Lieberman, J. A. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.12.1724 · Cited by 194 · see citing works

Premorbid functioning versus duration of untreated psychosis in 1 year outcome in first-episode psychosis

Larsen, T. K., Moe, L. C., Vibe-Hansen, L., & Johannessen, J. O. (2000) · Schizophrenia Research · doi:10.1016/s0920-9964(99)00169-3 · Cited by 193 · see citing works

Course of treatment response in first-episode and chronic schizophrenia

Szymanski, S., Cannon, T. D., Gallacher, F., Erwin, R. J., & Gur, R. E. (1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.4.519 · Cited by 154 · see citing works

Testing Systems for Assessment of Negative Symptoms in Schizophrenia

Fenton, W. S. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820030011002 · Cited by 154 · see citing works

Three syndrome concept of schizophrenia

MALLA, A. K., Norman, R. M. G., Williamson, P., Cortese, L., & Diaz, F. (1993) · Schizophrenia Research · doi:10.1016/0920-9964(93)90049-o · Cited by 139 · see citing works

The Dimensions of Schizophrenia Phenomenology Not one or two, at least three, perhaps four

Lenzenweger, M. F., & Dworkin, R. H. (1996) · The British Journal of Psychiatry · doi:10.1192/bjp.168.4.432 · Cited by 135 · see citing works

Empirical Validation of Primary Negative Symptoms: Independence From Effects of Medication and Psychosis

Kelley, M. E., van Kammen, D. P., & Allen, D. N. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.3.406 · Cited by 118 · see citing works

Neuropsychological correlates of syndromes in schizophrenia

Norman, R. M. G., MALLA, A. K., Morrison-Stewart, S. L., Helmes, E., Williamson, P. C., Thomas, J., & Cortese, L. (1997) · The British Journal of Psychiatry · doi:10.1192/bjp.170.2.134 · Cited by 117 · see citing works

Enduring negative symptoms in first-episode psychosis: comparison of six methods using follow-up data

Edwards, J., McGorry, P. D., Waddell, F. M., & Harrigan, S. (1999) · Schizophrenia Research · doi:10.1016/s0920-9964(99)00043-2 · Cited by 109 · see citing works

Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms

Keefe, R. S. E., Harvey, P. D., Lenzenweger, M. F., Davidson, M., Apter, S. H., Schmeidler, J., Mohs, R. C., & Davis, K. L. (1992) · Psychiatry Research · doi:10.1016/0165-1781(92)90049-9 · Cited by 107 · see citing works

Relationships between changes in symptom ratings, neuropsychological test performance and quality of life in schizophrenic patients treated with clozapine

Galletly, C. A., Clark, C. R., McFARLANE, A. C., & Weber, D. L. (1997) · Psychiatry Research · doi:10.1016/s0165-1781(97)00062-0 · Cited by 103 · see citing works

Syndromes of Chronic Schizophrenia and Some Clinical Correlates

Brown, K. W., & White, T. G. (1992) · The British Journal of Psychiatry · doi:10.1192/bjp.161.3.317 · Cited by 90 · see citing works

Differentiating Primary From Secondary Negative Symptoms in Schizophrenia: A Study of Neuroleptic-Naive Patients Before and After Treatment

Peralta, V., Cuesta, M. J., Martínez‐Larrea, A., & Serrano, J. F. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.9.1461 · Cited by 86 · see citing works

Implicit and explicit associative memory in patients with schizophrenia

Bazin, N., & Perruchet, P. (1996) · Schizophrenia Research · doi:10.1016/s0920-9964(96)00052-7 · Cited by 62 · see citing works

Negative Symptoms and Affective Disturbance in Schizophrenia and Related Disorders

Malla, A. (1995) · The Canadian Journal of Psychiatry · doi:10.1177/070674379504007s05 · Cited by 16 · see citing works

The Differential Diagnosis of Negative Symptoms in Chronic Schizophrenia

Whiteford, H., & Peabody, C. A. (1989) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048678909062616 · Cited by 9 · see citing works

Anhedonia in schizophrenia: Distinctions between anticipatory and consummatory pleasure

Gard, D. E., Kring, A. M., Gard, M. G., Horan, W. P., & Green, M. F. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.03.008 · Cited by 817 · see citing works

Goal Representations and Motivational Drive in Schizophrenia: The Role of Prefrontal-Striatal Interactions

Barch, D. M., & Dowd, E. C. (2010) · Schizophrenia Bulletin · doi:10.1093/schbul/sbq068 · Cited by 478 · see citing works

Deconstructing negative symptoms of schizophrenia: Avolition–apathy and diminished expression clusters predict clinical presentation and functional outcome

Strauss, G. P., Horan, W. P., Kirkpatrick, B. W., Fischer, B. A., Keller, W. R., Miski, P., Buchanan, R. W., Green, M. F., & Carpenter, W. T. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.01.015 · Cited by 424 · see citing works

First-Episode Psychosis: Psychopathology, Quality of Life, and Functional Outcome

MALLA, A. K. (2005) · Schizophrenia Bulletin · doi:10.1093/schbul/sbi031 · Cited by 284 · see citing works

Avolition and expressive deficits capture negative symptom phenomenology: Implications for DSM-5 and schizophrenia research

Messinger, J. W., Trémeau, F., Antonius, D., Mendelsohn, E., Prudent, V., Stanford, A. D., & Malaspina, D. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2010.09.002 · Cited by 271 · see citing works

Negative symptoms of schizophrenia: Clinical features, relevance to real world functioning and specificity versus other CNS disorders

Foussias, G., Agid, O., Fervaha, G., & Remington, G. J. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.10.017 · Cited by 250 · see citing works

Duration of untreated psychosis and negative symptoms — A systematic review and meta-analysis of individual patient data

Boonstra, N., Klaassen, R. M. C., Sytema, S., Marshall, M., de Haan, L., Wunderink, L., & Wiersma, D. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.08.017 · Cited by 241 · see citing works

Patients with schizophrenia demonstrate dissociation between affective experience and motivated behavior.

Heerey, E. A., & Gold, J. M. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.2.268 · Cited by 237 · see citing works

Logic and justification for dimensional assessment of symptoms and related clinical phenomena in psychosis: Relevance to DSM-5

Barch, D. M., Bustillo, J., Gäebel, W., Gur, R., Heckers, S., Malaspina, D., Owen, M. J., Schultz, S. K., Tandon, R., Tsuang, M. T., et al. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.04.027 · Cited by 220 · see citing works

Acting on persecutory delusions: The importance of safety seeking

Freeman, D. H., Garety, P. A., Kuipers, E., Fowler, D. G., Bebbington, P., & Dunn, G. (2006) · Behaviour Research and Therapy · doi:10.1016/j.brat.2006.01.014 · Cited by 219 · see citing works

Psychological and psychosocial interventions for negative symptoms in psychosis: Systematic review and meta-analysis

Lutgens, D., Gariepy, G., & Malla, A. (2017) · British Journal of Psychiatry · doi:10.1192/bjp.bp.116.197103 · Cited by 181 · see citing works

Stress and protective factors in individuals at ultra-high risk for psychosis, first episode psychosis and healthy controls

Pruessner, M., Iyer, S. N., Faridi, K., Joober, R., & MALLA, A. K. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.03.022 · Cited by 188 · see citing works

Negative symptoms in schizophrenia—A review

Mäkinen, J., Miettunen, J., Isohanni, M. K., & Koponen, H. (2008) · Nordic Journal of Psychiatry · doi:10.1080/08039480801959307 · Cited by 173 · see citing works

Inflammation in first‐episode psychosis: The contribution of inflammatory biomarkers to the emergence of negative symptoms, a systematic review and meta‐analysis

Dunleavy, C., Elsworthy, R. J., Upthegrove, R., Wood, S. J., & Aldred, S. (2022) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13416 · Cited by 169 · see citing works

Is Adolescent-Onset First-Episode Psychosis Different From Adult Onset?

Ballageer, T., MALLA, A. K., Manchanda, R., Takhar, J., & Haricharan, R. (2005) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000164591.55942.ea · Cited by 158 · see citing works

Duration of untreated psychosis and its relationship to clinical outcome

Norman, R. M. G., Lewis, S. W., & Marshall, M. (2005) · The British Journal of Psychiatry · doi:10.1192/bjp.187.48.s19 · Cited by 147 · see citing works

Primary and persistent negative symptoms: Concepts, assessments and neurobiological bases

Mucci, A., Merlotti, E., Üçok, A., Aleman, A., & Galderisi, S. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.05.014 · Cited by 141 · see citing works

The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors

Fleischhacker, W., Galderisi, S., Laszlovszky, I., Szatmári, B., Barabássy, Á., Acsai, K., Szalai, E., Harsányi, J., Earley, W. R., Patel, M., et al. (2019) · European Psychiatry · doi:10.1016/j.eurpsy.2019.01.015 · Cited by 115 · see citing works

Individual negative symptoms and domains – Relevance for assessment, pathomechanisms and treatment

Kaiser, S., Lyne, J., Agartz, I., Clarke, M., Mørch-Johnsen, L. E., & Færden, A. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.07.013 · Cited by 114 · see citing works

Can Patients at Risk for Persistent Negative Symptoms Be Identified During Their First Episode of Psychosis?

MALLA, A. K., Norman, R. M. G., Takhar, J., Manchanda, R., Townsend, L. A., Scholten, D. J., & Haricharan, R. (2004) · The Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000131804.34977.c1 · Cited by 113 · see citing works

Identifying persistent negative symptoms in first episode psychosis

Hovington, C. L., Bodnar, M. D., Joober, R., MALLA, A. K., & Lepage, M. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-224 · Cited by 89 · see citing works

Apathy in first episode psychosis patients: A ten year longitudinal follow-up study

Evensen, J. H., Røssberg, J. I., Barder, H. E., Haahr, U., Hegelstad, W. T. V., Joa, I., Johannessen, J. O., Larsen, T. K., Melle, I. S., Opjordsmoen, S., et al. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2011.12.019 · Cited by 86 · see citing works

Determinants of help-seeking and system related components of delay in the treatment of first-episode psychosis☆

Béchard‐Evans, L., Schmitz, N., Abadi, S., Joober, R., King, S., & MALLA, A. K. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.07.017 · Cited by 86 · see citing works

Neural substrates underlying effort computation in schizophrenia

Fervaha, G., Foussias, G., Agid, O., & Remington, G. J. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.09.001 · Cited by 79 · see citing works

Gender and duration of untreated psychosis: a systematic review and meta‐analysis

Cascio, M. T., Cella, M., Preti, A., Meneghelli, A., & Cocchi, A. (2012) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2012.00351.x · Cited by 81 · see citing works

The Evaluation and Management of Patients with First-Episode Schizophrenia: A Selective, Clinical Review of Diagnosis, Treatment, and Prognosis

Freudenreich, O., Holt, D. J., Cather, C., & GOFF, D. C. (2007) · Harvard Review of Psychiatry · doi:10.1080/10673220701679804 · Cited by 76 · see citing works

Neurocognition and neuroimaging of persistent negative symptoms of schizophrenia

Hovington, C. L., & Lepage, M. (2012) · Expert Review of Neurotherapeutics · doi:10.1586/ern.11.173 · Cited by 76 · see citing works

The neurocognitive underpinnings of diminished expressivity in schizotypy: What the voice reveals

Cohen, A. S., Iglesias, B., & Minor, K. S. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2009.01.010 · Cited by 74 · see citing works

Assessing apathy: The use of the Apathy Evaluation Scale in first episode psychosis

Faerden, A., Nesvåg, R., Barrett, E. A., Agartz, I., Finset, A., Friis, S., Rossberg, J. I., & Melle, I. (2008) · European Psychiatry · doi:10.1016/j.eurpsy.2007.09.002 · Cited by 73 · see citing works

Neuropsychological functions predict 1‐ and 3‐year outcome in first‐episode psychosis

Carlsson, R., Nyman, H., Ganse, G., & Cullberg, J. (2005) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2005.00661.x · Cited by 71 · see citing works

Duration of untreated psychosis: Relationship with baseline characteristics and three-year outcome in first-episode psychosis

Chang, W. C., Tang, J. Y. ‐., Hui, C. L. M., Lam, M. M. L., Wong, G. H. Y., Chan, S. K. W., Chiu, C. P. Y., Chung, D. W. S., Law, C. W., Tso, S., et al. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2011.09.006 · Cited by 64 · see citing works

Towards a cognitive resource limitations model of diminished expression in schizotypy.

Cohen, A. S., Morrison, S. C., Brown, L. A., & Minor, K. S. (2011) · Journal of Abnormal Psychology · doi:10.1037/a0023599 · Cited by 61 · see citing works

Static posed and evoked facial expressions of emotions in schizophrenia

Kohler, C. G., Martin, E. A., Stolar, N., Barrett, F. S., Verma, R., Brensinger, C., Bilker, W., Gur, R. E., & Gur, R. C. (2008) · Schizophrenia Research · doi:10.1016/j.schres.2008.05.010 · Cited by 59 · see citing works

Benefits of Enriched Intervention Compared with Standard Care for Patients with Recent-Onset Psychosis: A Metaanalytic Approach

Harvey, P., Lepage, M., & MALLA, A. K. (2007) · The Canadian Journal of Psychiatry · doi:10.1177/070674370705200709 · Cited by 59 · see citing works

Blunted cortisol awakening response in men with first episode psychosis: Relationship to parental bonding

Pruessner, M., Vracotas, N., Joober, R., Pruessner, J. C., & Malla, A. K. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.06.002 · Cited by 58 · see citing works

Flat affect and social functioning: A 10year follow-up study of first episode psychosis patients

Evensen, J. H., Røssberg, J. I., Barder, H. E., Haahr, U., Hegelstad, W. T. V., Joa, I., Johannessen, J. O., Larsen, T. K., Melle, I. S., Opjordsmoen, S., et al. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.04.019 · Cited by 56 · see citing works

Prevalence of item level negative symptoms in first episode psychosis diagnoses

Lyne, J., O'Donoghue, B. N., Owens, E., Renwick, L., Madigan, K. V., Kinsella, A., Clarke, M., Turner, N., & O’Callaghan, E. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.01.004 · Cited by 55 · see citing works

The relationship between depressive symptoms and negative symptoms in people with non-affective psychosis: a meta-analysis

Edwards, C. J., Garety, P., & Hardy, A. (2019) · Psychological Medicine · doi:10.1017/s0033291719002381 · Cited by 54 · see citing works

The Structural Neural Substrates of Persistent Negative Symptoms in First-Episode of Non-Affective Psychosis: A Voxel-Based Morphometry Study

Benoit, A., Bodnar, M. D., MALLA, A. K., Joober, R., & Lepage, M. (2012) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00042 · Cited by 52 · see citing works

Cognitive markers of short-term clinical outcome in first-episode psychosis

Bodnar, M. D., MALLA, A. K., Joober, R., & Lepage, M. (2008) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.107.040410 · Cited by 52 · see citing works

Gender Differences in Patients Presenting with First-Episode Psychosis in Hong Kong: A Three-Year Follow Up Study

Chang, W. C., Tang, J. Y. ‐., Hui, C. L. M., Chiu, C. P. Y., Lam, M. M. L., Wong, G. H. Y., Chung, D. W. S., Law, C. W., Tso, S., Chan, K., et al. (2011) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048674.2010.547841 · Cited by 50 · see citing works

The Prevalence of Negative Symptoms Across the Stages of the Psychosis Continuum

Sauvé, G., Brodeur, M. B., Shah, J. L., & Lepage, M. (2018) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000184 · Cited by 46 · see citing works

Alterations in facial expressivity in youth at clinical high-risk for psychosis.

Gupta, T., Haase, C. M., Strauss, G. P., Cohen, A. S., & Mittal, V. A. (2019) · Journal of Abnormal Psychology · doi:10.1037/abn0000413 · Cited by 44 · see citing works

Trajectories of premorbid childhood and adolescent functioning in schizophrenia-spectrum psychoses: A first-episode study

Horton, L. E., Tarbox, S. I., Olino, T. M., & Haas, G. L. (2015) · Psychiatry Research · doi:10.1016/j.psychres.2015.02.013 · Cited by 42 · see citing works

Understanding and Treating “First-Episode” Schizophrenia

Weiden, P. J., Buckley, P. F., & Grody, M. B. (2007) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2007.04.010 · Cited by 39 · see citing works

Dynamic evoked facial expressions of emotions in schizophrenia

Kohler, C. G., Martin, E. A., Milonova, M., Wang, P., Verma, R., Brensinger, C. M., Bilker, W. B., Gur, R. E., & Gur, R. C. (2008) · Schizophrenia Research · doi:10.1016/j.schres.2008.05.030 · Cited by 38 · see citing works

Age-related cortical thickness trajectories in first episode psychosis patients presenting with early persistent negative symptoms

Makowski, C., Bodnar, M. D., MALLA, A. K., Joober, R., & Lepage, M. (2016) · Schizophrenia · doi:10.1038/npjschz.2016.29 · Cited by 38 · see citing works

Follow-up of subjects with suspected pre-psychotic state in Taiwan

Liu, C., Lai, M., Liu, C., Chiu, Y., Hsieh, M. H., Hwang, T., Chien, Y., Chen, W. J., Hua, M., Hsiung, P., et al. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.10.028 · Cited by 35 · see citing works

Negative symptom subgroups have different effects on the clinical course of schizophrenia after the first episode: A 24-month follow up study

Ergül, C., & Üçok, A. (2014) · European Psychiatry · doi:10.1016/j.eurpsy.2014.07.005 · Cited by 34 · see citing works

Scale for the Assessment of Negative Symptoms structure in first episode psychosis

Lyne, J., Renwick, L., Grant, T., Kinsella, A., McCarthy, P., Malone, K. M., Turner, N., O’Callaghan, E., & Clarke, M. (2013) · Psychiatry Research · doi:10.1016/j.psychres.2013.09.008 · Cited by 33 · see citing works

Impairment in verbal memory observed in first episode psychosis patients with persistent negative symptoms

Hovington, C. L., Bodnar, M. D., Joober, R., MALLA, A. K., & Lepage, M. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.04.006 · Cited by 33 · see citing works

Understanding Constricted Affect in Schizotypy Through Computerized Prosodic Analysis

Cohen, A. S., & Hong, S. L. (2011) · Journal of Personality Disorders · doi:10.1521/pedi.2011.25.4.478 · Cited by 32 · see citing works

Sex Differences in Verbal Memory Predict Functioning Through Negative Symptoms in Early Psychosis

Buck, G., Lavigne, K. M., Makowski, C., Joober, R., MALLA, A. K., & Lepage, M. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa054 · Cited by 32 · see citing works

Examination of the P ositive and N egative S yndrome S cale factor structure and longitudinal relationships with functioning in early psychosis

Best, M. W., Grossman, M., Oyewumi, L. K., & Bowie, C. R. (2014) · Early Intervention in Psychiatry · doi:10.1111/eip.12190 · Cited by 32 · see citing works

Psychosis Incident Cohort Outcome Study (PICOS). A multisite study of clinical, social and biological characteristics, patterns of care and predictors of outcome in first-episode psychosis. Background, methodology and overview of the patient sample

Lasalvia, A., Tosato, S., Brambilla, P., Bertani, M., Bonetto, C., Cristofalo, D., Bissoli, S., Santi, K. D., Lazzarotto, L., Zanatta, G. D. A. C., et al. (2012) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796012000315 · Cited by 31 · see citing works

Duration of active psychosis and first‐episode psychosis negative symptoms

Lyne, J., Joober, R., Schmitz, N., Lepage, M., & MALLA, A. K. (2015) · Early Intervention in Psychiatry · doi:10.1111/eip.12217 · Cited by 31 · see citing works

Elucidating negative symptoms in the daily life of individuals in the early stages of psychosis

Hermans, K. S. F. M., Myin‐Germeys, I., Gayer-Anderson, C. E., Kempton, M. J., Valmaggia, L., McGuire, P. K., Murray, R. M., Garety, P. A., Wykes, T., Morgan, C., et al. (2020) · Psychological Medicine · doi:10.1017/s0033291720001154 · Cited by 29 · see citing works

Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis

Chang, W. C., Lau, C. F. C., Chan, S. S. I., Hui, C. L. M., Chan, S. K. W., Lee, E. H. M., Lin, J., & Chen, E. Y. H. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.05.045 · Cited by 29 · see citing works

Investigation of white matter abnormalities in first episode psychosis patients with persistent negative symptoms

Hovington, C. L., Bodnar, M. D., Chakravarty, M. M., Joober, R., MALLA, A. K., & Lepage, M. (2015) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2015.06.017 · Cited by 28 · see citing works

A study on negative and depressive symptom prevalence in individuals at ultra‐high risk for psychosis

Azar, M., Pruessner, M., Baer, L. H., Iyer, S. N., MALLA, A. K., & Lepage, M. (2016) · Early Intervention in Psychiatry · doi:10.1111/eip.12386 · Cited by 28 · see citing works

Family context and duration of untreated psychosis (DUP): Results from the Sao Paulo Study

de Oliveira, A. M., Menezes, P. R., Busatto, G. F., McGuire, P. K., Murray, R. M., & Scazufca, M. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2009.08.018 · Cited by 28 · see citing works

Impact of Negative Symptoms on Functioning and Quality of Life in First Psychotic Episodes of Schizophrenia

Fernandez, L. G., Romero‐Ferreiro, V., Sánchez-Pastor, L., Dompablo, M., Martínez‐Gras, I., Espejo-Saavedra, J. M., Rentero, D., Aparicio, A. I., Álvarez-Mon, M. Á., Lahera, G., et al. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11040983 · Cited by 27 · see citing works

Clinical and functional implications of a history of childhood ADHD in first-episode psychosis.

Rho, A., Traicu, A., Lepage, M., Iyer, S., Malla, A., & Joober, R. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.03.031 · Cited by 26 · see citing works

Neurodevelopmental markers in different psychopathological dimensions of first episode psychosis: The ESPIGAS Study

Ruíz-Veguilla, M., Cervilla, J. A., Barrigón, M. L., Ferrín, M., Gutiérrez, B., Gordo, E., Anguita, M., Brañas, A., Fernández-Logroño, J., & Manuel Gurpegui, A. (2008) · European Psychiatry · doi:10.1016/j.eurpsy.2008.04.003 · Cited by 24 · see citing works

Catechol‐O‐methyltransferaseVal158Metpolymorphism and clinical characteristics in first episode non‐affective psychosis

Pelayo‐Terán, J. M., Crespo‐Facorro, B., Carrasco-Marı́n, E., Pérez‐Iglesias, R., Mata, I. F., Arranz, M. J., Leyva‐Cobián, F., & Vázquez‐Barquero, J. L. (2007) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30639 · Cited by 24 · see citing works

Dimensional Information-Theoretic Measurement of Facial Emotion Expressions in Schizophrenia

Hamm, J., Pinkham, A. E., Gur, R. C., Verma, R., & Kohler, C. G. (2014) · Schizophrenia Research and Treatment · doi:10.1155/2014/243907 · Cited by 24 · see citing works

The hormonal environment in utero as a potential aetiological agent for schizophrenia

Procopio, M., Davies, R. J. E., & Marriott, P. K. (2005) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-005-0604-8 · Cited by 24 · see citing works

A qualitative study of the acceptability of cognitive bias modification for paranoia (CBM-pa) in patients with psychosis

Leung, C. J., Fosuaah, A., Frerichs, J., Heslin, M., Kabir, T., Lee, T. M. C., McGuire, P., Meek, C., Mouchlianitis, E., Nath, A. S., et al. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2215-3 · Cited by 20 · see citing works

Progress of negative symptoms over the initial 5 years of a first episode of psychosis

Lutgens, D., Joober, R., Iyer, S. N., Lepage, M., Norman, R. M. G., Schmitz, N., Mustafa, S., Abadi, S., & MALLA, A. K. (2018) · Psychological Medicine · doi:10.1017/s003329171800048x · Cited by 23 · see citing works

Interaction of negative olfactory stimulation and working memory in schizophrenia patients: Development and evaluation of a behavioral neuroimaging task

Schneider, F. W., Koch, K., Reske, M., Kellermann, T., Romanczuk‐Seiferth, N., Stöcker, T., Amunts, K., Shah, N. J., & Habel, U. (2006) · Psychiatry Research · doi:10.1016/j.psychres.2004.12.013 · Cited by 23 · see citing works

The course of negative symptoms over the first five years of treatment: Data from an early intervention program for psychosis

Norman, R. M. G., Manchanda, R., Harricharan, R., & Northcott, S. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.09.010 · Cited by 22 · see citing works

Social Cognition, Negative Symptoms and Psychosocial Functioning in Schizophrenia

Madeira, N. G. G. F., Caldeira, S., Bajouco, M., Pereira, A. T., Martins, M. J., & Macedo, A. (2016) · International Journal of Clinical Neurosciences and Mental Health · doi:10.21035/ijcnmh.2016.3.1 · Cited by 20 · see citing works

Early intervention in psychosis: specialized intervention and early case identification

MALLA, A. K., Lal, S., Vracotas, N., Goldberg, K. A., & Joober, R. (2010) · L Encéphale · doi:10.1016/s0013-7006(10)70029-4 · Cited by 20 · see citing works

Prevalence and correlates of PTSD in first episode psychosis: Findings from the RAISE-ETP study.

DeTore, N. R., Gottlieb, J. D., & Mueser, K. T. (2019) · Psychological Services · doi:10.1037/ser0000380 · Cited by 17 · see citing works

Prediction of motivational impairment: 12-month follow-up of the randomized-controlled trial on extended early intervention for first-episode psychosis

Chang, W. C., Kwong, V. W. Y., Chan, G. H. K., Jim, O. T. T., Lau, E. S. K., Hui, C. L. M., Chan, S. K. W., Lee, E. H. M., & Chen, E. Y. H. (2017) · European Psychiatry · doi:10.1016/j.eurpsy.2016.09.007 · Cited by 17 · see citing works

Genetically modified mice related to schizophrenia and other psychoses: Seeking phenotypic insights into the pathobiology and treatment of negative symptoms

O’Tuathaigh, C. M. P., Desbonnet, L., & Waddington, J. L. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.08.009 · Cited by 14 · see citing works

Motion energy analysis during speech tasks in medication-naïve individuals with at-risk mental states for psychosis

Lopes-Rocha, A., Corcoran, C., Andrade, J. C., Peroni, L., Haddad, N. M., Hortêncio, L., Serpa, M., van de Bilt, M. T., Gattaz, W., & Loch, A. (2022) · Schizophrenia · doi:10.1038/s41537-022-00283-3 · Cited by 14 · see citing works

Altered hippocampal centrality and dynamic anatomical covariance of intracortical microstructure in first episode psychosis

Makowski, C., Lewis, J. D., Khundrakpam, B. S., Tardif, C. L., Palaniyappan, L. K., Joober, R., MALLA, A. K., Shah, J. L., Bodnar, M. D., Chakravarty, M. M., et al. (2020) · Hippocampus · doi:10.1002/hipo.23215 · Cited by 13 · see citing works

Relationship of negative symptom severity with cognitive symptoms and functioning in subjects at ultra‐high risk for psychosis

Üçok, A., Direk, N., Kaya, H., Çağlar, N., Çıkrıkçılı, U., Noyan, H., Yokuşoğlu, Ç., & Devrim‐Üçok, M. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.13042 · Cited by 13 · see citing works

Meta-analysis of the factor structure of the Scale for the Assessment of Negative Symptoms (SANS) and the Scale for the Assessment of Positive Symptoms (SAPS)

Dazzi, F., & Shafer, A. (2024) · Schizophrenia Research · doi:10.1016/j.schres.2024.10.027 · Cited by 10 · see citing works

Comparison of Psychosocial Determinants in Inpatients With First-Episode and Chronic Schizophrenia in China

Mwansisya, T. E., Yi, W., Wang, Z., Yang, B. Y., Li, L., Wang, P., Liu, C., Wu, G., Xue, Z., & Liu, Z. (2012) · Archives of Psychiatric Nursing · doi:10.1016/j.apnu.2012.08.001 · Cited by 10 · see citing works

Bipolar disorder risk gene FOXO6 modulates negative symptoms in schizophrenia: a neuroimaging genetics study

Shenker, J. J., Sengupta, S. M., Joober, R., MALLA, A. K., Chakravarty, M. M., & Lepage, M. (2017) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.150332 · Cited by 9 · see citing works

Medial temporal lobe and basal ganglia volume trajectories in persistent negative symptoms following a first episode of psychosis

Lavigne, K. M., Raucher‐Chéné, D., Bodnar, M. D., Makowski, C., Joober, R., MALLA, A. K., Evans, A. C., & Lepage, M. (2022) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2022.110551 · Cited by 8 · see citing works

Where are patients who have co-occurring mental and physical diseases located?

Toftegaard, K. L., Gustafsson, L. N., Uwakwe, R., Andersen, U. A., Becker, T. M., Bickel, G. G., Bork, B., Cordes, J., Frasch, K., Jacobsen, B. A., et al. (2014) · International Journal of Social Psychiatry · doi:10.1177/0020764014552866 · Cited by 7 · see citing works

Pathways to care and reducing treatment delay in early psychosis

Norman, R. M. G., & MALLA, A. K. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511576287.011 · Cited by 7 · see citing works

The trajectories and correlates of two negative symptom subdomains in first-episode schizophrenia

Phahladira, L., Asmal, L., Luckhoff, H. K., du Plessis, S. S., Scheffler, F., Smit, R., Chiliza, B., & Emsley, R. A. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.02.017 · Cited by 7 · see citing works

Cariprazine as a treatment for negative psychotic symptoms in first-episode psychosis: case series

Demjaha, A., Iacoponi, E., Hansen, L. K., Peddu, P., & McGuire, P. K. (2022) · BJPsych Open · doi:10.1192/bjo.2022.56 · Cited by 7 · see citing works

Psychosis and Schizophrenia

Freudenreich, O., Weiss, A. P., & GOFF, D. C. (2008) · Elsevier eBooks · doi:10.1016/b978-0-323-04743-2.50030-5 · Cited by 7 · see citing works

Exploring the factor structure of the PTSD checklist for DSM–5 in psychotic disorders.

Penney, D., El‐Baalbaki, G., & Lepage, M. (2021) · Psychological Trauma Theory Research Practice and Policy · doi:10.1037/tra0001146 · Cited by 7 · see citing works

VALIDACIÓN DE UNA ESCALA DE CALIDAD DE VIDA EN UN GRUPO DE PERSONAS CON ESQUIZOFRENIA DE LA REGION METROPOLITANA - CHILE

Dois, A., Contreras, A., Mantuliz, M. C. A., & María Teresa Urrutia, S. (2007) · Ciencia y enfermería/Ciencia y enfermería · doi:10.4067/s0717-95532007000100005 · Cited by 6 · see citing works

Efficacy of amisulpride in treating primary negative symptoms in first-episode psychosis: a pilot study

Murphy, B., Stuart, A. H., Wade, D., Cotton, S., & McGorry, P. D. (2006) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.807 · Cited by 6 · see citing works

First-episode psychosis: An update

Chiliza, B., Oosthuizen, P. P., & Emsley, R. A. (2008) · South African Journal of Psychiatry · doi:10.4102/sajpsychiatry.v14i1.83 · Cited by 6 · see citing works

Gesticulation in individuals with at risk mental states for psychosis

Lopes-Rocha, A. C., Ramos, W. H. D. P., Argôlo, F. C., Gondim, J. M., Mota, N. B., Andrade, J. C., Jafet, A. F., de Medeiros, M. W., Serpa, M. H., Cecchi, G., et al. (2023) · Schizophrenia · doi:10.1038/s41537-023-00360-1 · Cited by 5 · see citing works

Sex-specific associations in verbal memory brain circuitry in early psychosis

Buck, G., Makowski, C., Chakravarty, M. M., Mišić, B., Joober, R., MALLA, A. K., Lepage, M., & Lavigne, K. M. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.05.006 · Cited by 5 · see citing works

Normal-range verbal memory in the first-episode of psychosis: Clinical and functional outcomes across 24 months and impact of estimated verbal memory decrement

Raucher‐Chéné, D., Pochiet, G., Lavigne, K. M., Heinrichs, R. W., MALLA, A. K., Joober, R., & Lepage, M. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.06.007 · Cited by 4 · see citing works

Intersection of verbal memory and expressivity on cortical contrast and thickness in first episode psychosis

Makowski, C., Lewis, J. D., Lepage, C., MALLA, A. K., Joober, R., Evans, A. C., & Lepage, M. (2019) · Psychological Medicine · doi:10.1017/s0033291719002071 · Cited by 4 · see citing works

Duration of Untreated Psychosis and Pathways to Care

Brunet, K., & Birchwood, M. J. (2010) · doi:10.1002/9781444318814.ch2 · Cited by 3 · see citing works

Negative symptoms in drug-naive patients with a first-episode psychosis (FEP)

Cuñat, O., Hoyo, B., Vila‐Badia, R., Serra‐Arumí, C., Butjosa, A., Cacho, N. D., Colomer-Salvans, A., Dolz, M., Cuevas‐Esteban, J., Iglesias-González, M., et al. (2023) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2023.103448 · Cited by 2 · see citing works

From resting-state functional hippocampal centrality to functional outcome: An extended neurocognitive model of psychosis

Totzek, J. F., Shah, J. L., Young, A. L., MALLA, A. K., Joober, R., Raucher‐Chéné, D., Lepage, M., & Lavigne, K. M. (2025) · Psychiatry Research · doi:10.1016/j.psychres.2025.116538 · Cited by 1 · see citing works

Estrés y factores protectores en individuos en riesgo ultra-alto de psicosis, pacientes con un primer episodio de psicosis e individuos de control sanos

Pruessner, M., Iyer, S. N., Faridi, K., Joober, R., & MALLA, A. K. (2012) · Psiquiatría Biológica · doi:10.1016/j.psiq.2012.09.006 · Cited by 1 · see citing works

Duration of untreated psychosis is associated with more negative schizophrenia symptoms after acute treatment for first-episode psychosis

Granö, N., Lindsberg, J., Karjalainen, M., Grönroos, P., & Blomberg, A.-P. (2010) · Clinical Psychologist · doi:10.1080/13284201003662826 · Cited by 5 · see citing works

Can Patients at Risk for Persistent Negative Symptoms Be Identified During Their First Episode of Psychosis?

MALLA, A. K., Norman, R. M. G., Takhar, J., Manchanda, R., Townsend, L. A., Scholten, D. J., & Haricharan, R. (2004) · The Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000131804.34977.c1 · Cited by 113 · see citing works

The incidence of negative symptoms in early schizophrenia, mania and other psychoses

Montague, L. R., Tantam, D., Newby, D., Thomas, P., & Ring, N. (1989) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1989.tb10310.x · Cited by 26 · see citing works

Time is the enemy: Negative symptoms are related to even slight differences in the duration of untreated psychosis

Slováková, A., Kudelka, J., Škoch, A., Jakob, L., Fialová, M., Fürstová, P., Bakštein, E., Motlová, L. B., Knytl, P., & Španiel, F. (2024) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2024.152450 · Cited by 8 · see citing works

T119. NO DIFFERENCE BETWEEN VOLITIVE AND EXPRESSIVE NEGATIVE SYMPTOMS FOR EARLY TREATMENT RESPONSE IN FIRST EPISODE OF PSYCHOSIS ANTIPSYCHOTIC NAïVE PATIENTS

Haguiara, B., Tonsig, G., Kagan, S., Cavalcante, D. A., Noto, C. D. S., Bressan, R. A., & Gadelha, A. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa029.679