Perceived self-efficacy and pain control: Opioid and nonopioid mechanisms.

Abstract

In this experiment, we tested for opioid and nonopioid mechanisms of pain control through cognitive means and the relation of opioid involvement to perceived coping efficacy. Subjects were taught cognitive methods of pain control, were administered a placebo, or received no intervention. Their pain tolerance was then measured at periodic intervals after they were administered either a saline solution or naloxone, an opiate antagonist that blocks the effects of endogenous opiates. Training in cognitive control strengthened perceived self-efficacy both to withstand and to reduce pain; placebo medication enhanced perceived efficacy to withstand pain but not reductive efficacy; and neither form of perceived self-efficacy changed without any intervention. Regardless of condition, the stronger the perceived self-efficacy to withstand pain, the longer subjects endured mounting pain stimulation. The findings provide evidence that attenuation of the impact of pain stimulation through cognitive control is mediated by both opioid and nonopioid mechanisms. Cognitive copers administered naloxone were less able to tolerate pain stimulation than were their saline counterparts. The stronger the perceived self-efficacy to reduce pain, the greater was the opioid activation. Cognitive copers were also able to achieve some increase in pain tolerance even when opioid mechanisms were blocked by naloxone, which is in keeping with a nonopioid component in cognitive pain control. We found suggestive…

Cites (1)

1. Organization of endogenous opiate and nonopiate pain control systems
   Watkins, Linda R., Mayer, David J. · 1982 · Science

Cited by (25)

1. The biopsychosocial approach to chronic pain: Scientific advances and future directions.
   Gatchel, Robert J., Peng, Yuan Bo, Peters, Madelon L., Fuchs, Perry N., Turk, Dennis C. · 2007 · Psychological Bulletin
2. Theoretical perspectives on the relation between catastrophizing and pain
   Sullivan, Michael J. L., Thorn, Beverly, Haythornthwaite, Jennifer A., Keefe, Francis, Martin, Michelle, Bradley, Laurence A., Lefebvre, John C. · 2001 · The Clinical Journal of Pain
3. The pain self-efficacy questionnaire: Taking pain into account
   Nicholas, Michael K. · 2007 · European Journal of Pain
4. Effects of mindfulness-based stress reduction on medical and premedical students
   Shapiro, Shauna L., Schwartz, Gary E., Bonner, Ginny · 1998 · Journal of Behavioral Medicine
5. Dispositional optimism and recovery from coronary artery bypass surgery: The beneficial effects on physical and psychological well-being.
   Scheier, Michael F., Matthews, Karen A., Owens, Jane F., Magovern, George J., Lefebvre, R. Craig, Abbott, R. Anne, Carver, Charles S. · 1989 · Journal of Personality and Social Psychology
6. The social risk hypothesis of depressed mood: evolutionary, psychosocial, and neurobiological perspectives
   Allen, Nicholas B., Badcock, Paul B. T. · 2003 · Psychological Bulletin
7. Sex, gender, and pain: women and men really are different
   Fillingim, Roger B. · 2000 · Current Review of Pain
8. Allostatic Self-efficacy: A Metacognitive Theory of Dyshomeostasis-Induced Fatigue and Depression
   Stephan, Klaas E., Manjaly, Zina M., Mathys, Christoph D., Weber, Lilian A. E., Paliwal, Saee, Gard, Tim, Tittgemeyer, Marc, Fleming, Stephen M., Haker, Helene, Seth, Anil K. et al. · 2016 · Frontiers in Human Neuroscience
9. Development and initial validation of a scale to measure self-efficacy beliefs in patients with chronic pain
   Anderson, Karen O., Dowds, Barbara Noel, Pelletz, Robyn E., Edwards, Thomas W., Peeters-Asdourian, Christine · 1995 · Pain
10. Self efficacy as a mediator of the relationship between pain intensity, disability and depression in chronic pain patients
    Arnstein, Paul, Caudill, Margaret, Mandle, Carol Lynn, Norris, Anne, Beasley, Ralph · 1999 · Pain
11. Mindfulness meditation-based pain relief: a mechanistic account
    Zeidan, Fadel, Vago, David R. · 2016 · Annals of the New York Academy of Sciences
12. The effects of mindfulness-based stress reduction on psychosocial outcomes and quality of life in early-stage breast cancer patients: a randomized trial
    Henderson, Virginia P., Clemow, Lynn, Massion, Ann O., Hurley, Thomas G., Druker, Susan, Hébert, James R. · 2012 · Breast Cancer Research and Treatment
13. The Effect of Manipulated Self-Efficacy on Perceived and Sustained Effort
    Hutchinson, Jasmin C., Sherman, Todd, Martinovic, Nevena, Tenenbaum, Gershon · 2008 · Journal of Applied Sport Psychology
14. Mindfulness-meditation-based pain relief is not mediated by endogenous opioids
    Zeidan, Fadel, Adler-Neal, Adrienne L., Wells, Rebecca E., Stagnaro, Emily, May, Lisa M., Eisenach, James C., McHaffie, John G., Coghill, Robert C. · 2016 · The Journal of Neuroscience
15. Self‐efficacy for arthritis pain: Relationship to perception of thermal laboratory pain stimuli
    Keefe, Francis J., Lefebvre, John C., Maixner, William, Salley, Alfred N., Caldwell, David S. · 1997 · Arthritis & Rheumatism
16. Experiential Avoidance and Emotion Regulation in Borderline Personality Disorder
    Chapman, Alexander L., Dixon-Gordon, Katherine L., Walters, Kristy N. · 2011 · Journal of Rational-Emotive & Cognitive-Behavior Therapy
17. Reduction of conditioned pain modulation in humans by naltrexone: an exploratory study of the effects of pain catastrophizing
    King, Christopher D., Goodin, Burel, Kindler, Lindsay L., Caudle, Robert M., Edwards, Robert R., Gravenstein, Nikolaus, Riley, Joseph L., Fillingim, Roger B. · 2013 · Journal of Behavioral Medicine
18. The Pain Self‐Efficacy Questionnaire: Cross‐Cultural Adaptation into Italian and Assessment of Its Measurement Properties
    Chiarotto, Alessandro, Vanti, Carla, Ostelo, Raymond W., Ferrari, Silvano, Tedesco, Giuseppe, Rocca, Barbara, Pillastrini, Paolo, Monticone, Marco · 2015 · Pain Practice
19. Migraine education improves quality of life in a primary care setting
    Smith, Timothy R., Nicholson, Robert A., Banks, James W. · 2010 · Headache: The Journal of Head and Face Pain
20. Relaxation: Some limitations, side effects, and proposed solutions.
    Lazarus, Arnold A., Mayne, Tracy J. · 1990 · Psychotherapy: Theory, Research, Practice, Training
21. Psychological factors predict an unfavorable pain trajectory after hysterectomy: a prospective cohort study on chronic postsurgical pain
    Pinto, Patrícia R., McIntyre, Teresa, Araújo-Soares, Vera, Almeida, Armando, Costa, Patrício · 2018 · Pain
22. Factors Related to Migraine Patients’ Decisions to Initiate Behavioral Migraine Treatment Following a Headache Specialist’s Recommendation: A Prospective Observational Study
    Minen, Mia T, Azarchi, Sarah, Sobolev, Rachel, Shallcross, Amanda, Halpern, Audrey, Berk, Thomas, Simon, Naomi M, Powers, Scott, Lipton, Richard B, Seng, Elizabeth · 2018 · Pain Medicine
23. Emotional distress and pain tolerance in obsessive-compulsive disorder
    Hezel, Dianne M., Riemann, Bradley C., McNally, Richard J. · 2012 · Journal of Behavior Therapy and Experimental Psychiatry
24. The effect of self-efficacy on visual discrimination sensitivity
    Zacharopoulos, George, Binetti, Nicola, Walsh, Vincent, Kanai, Ryota · 2014 · PLoS ONE
25. Cognitive-Behavioral Therapy fOr Clinical Pain Control: A 15-Year Update and its Relationship to Hypnosis
    Tan, Siang-Yang, Leucht, Christopher A. · 1997 · International Journal of Clinical and Experimental Hypnosis