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Comorbidity of unipolar depression: II. Comorbidity with other mental disorders in adolescents and adults.
Abstract
The current and lifetime comorbidity of depressive (i.e., major depressive disorder and dysthymia) with other common mental disorders was examined in community samples of older adolescents (n = 1,710) and adults (n = 2,060). Current and lifetime histories of depression in the adolescents were highly comorbid with several other mental disorders. The adults had a lower but statistically significant degree of comorbidity, primarily with substance use disorder. Depression in both groups was more likely to occur after the other disorder rather than to precede it. Comorbidity did not affect the duration or severity of depression. Comorbidity in the adolescents was associated with greater frequency of suicidal behavior and treatment seeking. The findings suggest that early-onset depression is associated with a greater degree of comorbidity and may represent a more serious form of the disorder.
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“The second reason is the high incidence and comorbidity of depression with other mental disorders, often depression being the subsequent diagnosis (21).”
From Acceptance and commitment therapy in a psychiatric day hospital—A longitudinal naturalistic effectiveness trial (2023) · cites this paper as [21]
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Metadata
- Authors
- Rohde, P., Lewinsohn, P. M., & Seeley, J. R.
- Affiliations
- Oregon Research Institute (US)
- Venue
- Journal of Abnormal Psychology
- Published
- 1991-05
- Volume
- 100
- Issue
- 2
- Pages
- 214-222
- ISSN
- 0021-843X (ISSN-L)
- 1939-1846
- OpenAlex
- W2069083186
- Cited by
- 440
- References
- 38
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 4 · 2023: 9 · 2022: 11 · 2021: 8 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 10 · 2016: 9 · 2015: 14 · 2014: 15 · 2013: 14 · 2012: 20
- FWCI
- 18.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Abnormal Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh035672-05)
- National Institute on Aging (AG1449)
- National Institute of Mental Health (MH33572, MH 35672)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- major depressive disorder, comorbidities, dysthymia, adolescents, adults, substance use disorders, suicidal behavior, treatment seeking, early-onset depression, community sample
- MeSH terms
- Adolescent, Adult, Age Factors, Mental Disorders, Depressive Disorder, Female, Humans, Male, Suicide, Comorbidity, Prevalence
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