Cited by 255Schizophrenia research and treatmentMental Health and PsychiatryNeural and Behavioral Psychology Studies

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Context-processing deficits in schizophrenia: Diagnostic specificity, 4-week course, and relationships to clinical symptoms.

Barch, Deanna M., Carter, Cameron S., MacDonald, Angus W., Braver, Todd S., Cohen, Jonathan D.·2003·Journal of Abnormal Psychology

DOI 10.1037/0021-843x.112.1.132

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Abstract

Previous research on schizophrenia suggests that context-processing disturbances are one of the core cognitive deficits present in schizophia. However, it is not clear whether such deficits are specific to schizophrenia as compared with other psychotic disorders. To address this question, the authors administered a version of the AX Continuous Performance Test designed to assess context processing in a sample of healthy controls, patients with schizophrenia, and patients with other psychotic disorders. Participants were tested at index (when medication naive and experiencing their first contact with psychiatric services) and 4 weeks later, following medication treatment. At index, patients with schizophrenia and the psychotic comparison group demonstrated similar impairments in context processing. However, context-processing deficits improved in the psychotic comparison group at 4 weeks but did not improve in patients with schizophrenia.

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Authors: Barch, D. M., Carter, C. S., MacDonald, A. W., Braver, T. S., & Cohen, J. D.
Affiliations: Washington University in St. Louis (US)
ORCID: Barch, Deanna M.
Carter, Cameron S.
Braver, Todd S.
Cohen, Jonathan D.
Venue: Journal of Abnormal Psychology
Publisher: American Psychological Association (APA)
Published: 2003-02
Volume: 112
Issue: 1
Pages: 132-143
ISSN: 0021-843X (ISSN-L)
1939-1846
DOI: 10.1037/0021-843x.112.1.132
OpenAlex: W2151392566
Cited by: 255
References: 55
Citations by year: 2026: 3 · 2025: 4 · 2024: 8 · 2023: 3 · 2022: 7 · 2021: 4 · 2020: 9 · 2019: 14 · 2018: 10 · 2017: 10 · 2016: 11 · 2015: 7 · 2014: 6 · 2013: 22 · 2012: 8
FWCI: 12.44
Type: journal article
Language: en
Open access: closed
Locations: Journal of Abnormal Psychology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (MH47073, MH 45156, P50MH045156)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords: schizophrenia, context processing, cognitive impairment, psychosis, diagnostic specificity, antipsychotic drugs, symptom improvement, first-episode psychosis
MeSH terms: Adult, Cognition Disorders, Female, Humans, Male, Neuropsychological Tests, Psychotic Disorders, Random Allocation, Reaction Time, Schizophrenia, Semantics, Sensitivity and Specificity, Antipsychotic Agents

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Context-processing deficits in schizophrenia: Diagnostic specificity, 4-week course, and relationships to clinical symptoms.

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