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Using Dissertations to Examine Potential Bias in Child and Adolescent Clinical Trials.

McLeod, Bryce D., Weisz, John R.·2004·Journal of Consulting and Clinical Psychology

DOI 10.1037/0022-006x.72.2.235

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Abstract

The major youth psychotherapy meta-analyses have relied on published studies, which may have led to biased effect size estimates. To examine this possibility, the authors compared 121 dissertations with 134 published studies and found the following: (a) few differences on individual methodological variables, but, overall, stronger methodology in dissertations; (b) no differences in the steps taken to ensure treatment integrity; and (c) a mean dissertation effect size less than half that of published studies. The effect size difference remained robust across tests controlling for all reliable method differences. The findings suggest that dissertations are so strong, both methodologically and clinically, that they warrant inclusion in child psychotherapy meta-analyses and that previous meta-analyses, by excluding them, may have overestimated treatment effects.

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Authors: McLeod, B. D., & Weisz, J. R.
Affiliations: University of California, Los Angeles (US)
ORCID: McLeod, Bryce D.
Weisz, John R.
Venue: Journal of Consulting and Clinical Psychology
Publisher: American Psychological Association (APA)
Published: 2004
Volume: 72
Issue: 2
Pages: 235-251
ISSN: 0022-006X (ISSN-L)
1939-2117
DOI: 10.1037/0022-006x.72.2.235
OpenAlex: W2113339390
Cited by: 125
References: 291
Citations by year: 2026: 1 · 2025: 1 · 2024: 9 · 2023: 3 · 2022: 7 · 2021: 9 · 2020: 4 · 2019: 6 · 2018: 7 · 2017: 2 · 2016: 5 · 2015: 5 · 2014: 6 · 2013: 14 · 2012: 4
FWCI: 1.27
Type: journal article
Language: en
Open access: closed
Locations: Journal of Consulting and Clinical Psychology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5k05mh001161-05, 5r01mh049522-06)
National Institute of Mental Health (R01 MH 49522, F31MH064993, K05-MH01161, F31-MH64993-01)
Topics: Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Social Sciences › Psychology › Experimental and Cognitive Psychology › Psychology Research and Bibliometrics
Keywords: dissertations, child psychotherapy, adolescent psychotherapy, clinical trials, publication bias, effect size overestimation, meta-analysis, implementation fidelity, methodological quality, unpublished research
MeSH terms: Adolescent, Child, Clinical Trials as Topic, Academic Dissertations as Topic, Humans, Bias

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Using Dissertations to Examine Potential Bias in Child and Adolescent Clinical Trials.

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