Reduction in disability in a randomized controlled trial of telephone-administered cognitive-behavioral therapy.
Abstract
Objective The authors examined the efficacy of telephone-administered cognitive-behavioral therapy (T-CBT) and telephone-administered supportive emotion-focused therapy (T-SEFT) in reducing disability among disabled patients with multiple sclerosis and depression. Telephone administration of therapy allowed care to be delivered to a more disabled population. This is a secondary analysis of a randomized controlled trial; the primary outcome results for depression are reported in D. C. Mohr, S. L. Hart, L. Julian, C. Catledge, L. Honos-Webb, L. Vella, et al. (2005). Design A randomized controlled trial, comparing 16 weeks of T-CBT with T-SEFT. Main outcome measures Disability was measured using Guy's Neurological Disability Scale; fatigue was measured using the Fatigue Impact Scale; depression was measured using the Hamilton Depression Rating Scale and the Beck Depression Inventory-II. Results Patients in both treatments showed significant improvements in disability and fatigue. These improvements were related to reductions in depression. T-CBT produced significantly greater decreases in disability and fatigue, compared with T-SEFT, even after controlling for depression. The greater benefit of T-CBT on disability was mediated by physical fatigue. Conclusion These findings support the hypothesis that significant reductions in disability can be achieved by reducing depression in patients with multiple sclerosis. There was also evidence that further reductions could be achieved th…
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Several previous controlled trials of cognitive-behavioral interventions have shown benefits upon depression, fatigue, or anxiety in patients with MS.
“Several previous controlled trials of cognitive-behavioral interventions have shown benefits upon depression, fatigue, or anxiety in patients with MS.19,38,39”
From MS quality of life, depression, and fatigue improve after mindfulness training: A randomized trial (2010) · cites this paper as [38]
These and other studies have often used individual therapy, and findings have mainly focused upon single dimensions of well-being, e.g., depression or fatigue.
“However, these and other studies have often used individual therapy, and findings have mainly focused upon single dimensions of well-being, e.g., depression or fatigue.”
From MS quality of life, depression, and fatigue improve after mindfulness training: A randomized trial (2010) · cites this paper as [38]
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MS quality of life, depression, and fatigue improve after mindfulness training: A randomized trial
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- Authors
- Mohr, D. C., Hart, S., & Vella, L.
- Affiliations
- University of California, San Francisco (US)
- Venue
- Health Psychology
- Published
- 2007
- Volume
- 26
- Issue
- 5
- Pages
- 554-563
- ISSN
- 0278-6133 (ISSN-L)
- 1930-7810
- OpenAlex
- W2043396854
- Cited by
- 75
- References
- 5
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2023: 1 · 2021: 6 · 2020: 1 · 2019: 2 · 2018: 8 · 2017: 5 · 2015: 6 · 2014: 2 · 2013: 7 · 2012: 4
- FWCI
- 4.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Health Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (R01 MH59708)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Keywords
- multiple sclerosis, disability, depression, fatigue, fatigue management, Fatigue Impact Scale, Hamilton Depression Rating Scale, Beck Depression Inventory-II
- MeSH terms
- Adult, California, Female, Persons with Disabilities, Humans, Male, Middle Aged, Multiple Sclerosis, Telephone, Cognitive Behavioral Therapy, Treatment Outcome, Remote Consultation
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