Telephone-Based Cognitive–Behavioral Therapy for Depression in Parkinson Disease
Open accessAbstract
Background: Although face-to-face cognitive–behavioral therapy (CBT) was found to be beneficial for the treatment of depression in Parkinson disease (dPD) in a recent randomized-controlled trial, access to care was identified as a critical issue that needs to be addressed in order to improve the management of this nonmotor complication in PD. The purpose of this study was to examine the feasibility and effect of telephone-based CBT for dPD. Methods: Twenty-one depressed people with PD participated in a National Institutes of Health–sponsored uncontrolled pilot trial of telephone-based CBT in an academic medical center from October 2009 to February 2011. The Hamilton Depression Rating Scale was the primary outcome. Treatment was provided to people with PD for 10 weeks, modified for delivery over the phone, and supplemented with 4 separate phone-based caregiver educational sessions. Assessments were completed at baseline and 5 (midpoint), 10 (end-of-treatment), and 14 weeks (follow-up) post-enrollment. Results: Twenty (95%) people with PD completed the study treatment. Phone-based CBT was associated with significant improvements in depression, anxiety, negative thoughts, and coping. Mean Hamilton Depression Rating Scale change from baseline to week 10 was 7.91 points ( P < .001, Cohen d = 1.21). Conclusions: Telephone-based CBT may be a feasible and helpful approach for treating dPD and warrants further exploration in randomized-controlled trials. Results were comparable to those observed in the few in-person cognitive–behavioral treatment studies for dPD conducted to date.
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CBT is effective in Parkinson's disease patients even after a follow-up period on anxiety and coping measures.
“It has been shown that CBT is effective in PD patients even after a follow-up period on anxiety and coping measures [32].”
From BEWARE: Body awareness training in the treatment of wearing-off related anxiety in patients with Parkinson's disease: study protocol for a randomized controlled trial. (2015) · cites this paper as [32]
The Results (Secondary Outcomes; page not provided) report significant improvements in anxiety and positive-reframing coping, and the Discussion says treatment gains were maintained through a one-month follow-up. However, the paper describes CBT as associated with these gains and concludes it may be helpful; the claim’s unqualified statement that CBT was effective is stronger than the pilot study supports. Problem-focused coping did not significantly improve. (LLM, conf=0.86)
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- Authors
- Dobkin, R. D., Menza, M., Allen, L. A., Tiu, J., Friedman, J., Bienfait, K. L., Gara, M. A., & Mark, M. H.
- Affiliations
- University of Medicine and Dentistry of New Jersey (US)
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
- Corresponding author
- Dobkin, Roseanne D.
- ORCID
- Dobkin, Roseanne D.
- Venue
- Journal of Geriatric Psychiatry and Neurology
- Publisher
- SAGE Publications
- Published
- 2011-12
- Volume
- 24
- Issue
- 4
- Pages
- 206-214
- ISSN
- 0891-9887 (ISSN-L)
- 1552-5708
- PMC
- PMC3571630
- OpenAlex
- W1986404848
- Cited by
- 88
- References
- 54
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 3 · 2023: 9 · 2022: 2 · 2021: 5 · 2020: 6 · 2019: 9 · 2018: 8 · 2017: 4 · 2016: 5 · 2015: 10 · 2014: 7 · 2013: 12 · 2012: 2
- FWCI
- 9.36
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of Geriatric Psychiatry and Neurology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (K23NS052155)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Keywords
- telemedicine, feasibility, access to mental health care, caregiver education, anxiety, coping, negative automatic thoughts, non-motor symptoms
- MeSH terms
- Academic Medical Centers, Aged, Depression, Feasibility Studies, Female, Follow-Up Studies, Humans, Male, Middle Aged, Parkinson Disease, Pilot Projects, Psychiatric Status Rating Scales, Telephone, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Telemedicine
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