Cognitive behavioral therapy for psychogenic nonepileptic seizures
Abstract
Treatment trials for psychogenic nonepileptic seizures (PNES) are few, despite the high prevalence and disabling nature of the disorder. We evaluated the effect of cognitive behavioral therapy (CBT) on reduction of PNES. Secondary measures included psychiatric symptom scales and psychosocial variables. We conducted a prospective clinical trial assessing the frequency of PNES in outpatients treated using a CBT for PNES manual. Subjects diagnosed with video/EEG-confirmed PNES were treated with CBT for PNES conducted in 12 weekly sessions. Seizure calendars were charted prospectively. Twenty-one subjects enrolled, and 17 (81%) completed the CBT intervention. Eleven of the 17 completers reported no seizures by their final CBT session. Mean scores on scales of depression, anxiety, somatic symptoms, quality of life, and psychosocial functioning showed improvement from baseline to final session. CBT for PNES reduced the number of PNES and improved psychiatric symptoms, psychosocial functioning, and quality of life.
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The success rate of ReACT is higher than studies using CBT for PNES in adults.
“The success rate of ReACT is higher than studies using CBT for PNES in adults.”
From Retraining and control therapy for pediatric psychogenic non-epileptic seizures (2020) · cites this paper as [23]
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- Authors
- LaFrance, W. C., Miller, I. W., Ryan, C. E., Blum, A. S., Solomon, D. A., Kelley, J. E., & Keitner, G. I.
- Affiliations
- Brown University (US)
- ORCID
- Blum, Andrew S.
- Venue
- Epilepsy & Behavior
- Publisher
- Elsevier BV
- Published
- 2009-04
- Volume
- 14
- Issue
- 4
- Pages
- 591-596
- ISSN
- 1525-5050 (ISSN-L)
- OpenAlex
- W2065657467
- Cited by
- 215
- References
- 55
- Citations by year
- 2026: 11 · 2025: 8 · 2024: 3 · 2023: 9 · 2022: 7 · 2021: 9 · 2020: 20 · 2019: 7 · 2018: 14 · 2017: 9 · 2016: 8 · 2015: 15 · 2014: 24 · 2013: 20 · 2012: 18
- FWCI
- 10.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Epilepsy & Behavior (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Epilepsy research and treatment
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- psychogenic non-epileptic seizures, cognitive behavioral therapy, seizure frequency reduction, psychiatric symptoms, depression, anxiety, somatic symptoms, quality of life, psychosocial functioning
- MeSH terms
- Adult, Electroencephalography, Female, Humans, Male, Middle Aged, Prospective Studies, Psychiatric Status Rating Scales, Psychophysiologic Disorders, Quality of Life, Retrospective Studies, Seizures, Video Recording, Cognitive Behavioral Therapy, Chi-Square Distribution, Treatment Outcome, Statistics, Nonparametric
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