Sequencing of symptom emergence in anorexia nervosa, bulimia nervosa, binge eating disorder, and purging disorder and relations of prodromal symptoms to future onset of these disorders.
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The objective of this study was to characterize the temporal sequencing of symptom emergence for anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and purging disorder (PD), as well as to test whether prodromal symptoms increase risk for future onset of each type of eating disorder and compare the predictive effects to those of established risk factors. Data from four prevention trials that targeted high-risk young women with body image concerns (N = 1,952; Mage = 19.7, SD = 5.7) and collected annual diagnostic interview data over 3-year follow-up were combined to address these aims. Regarding behavioral symptoms, compensatory weight control behaviors typically emerged first for AN, BN, and PD, whereas binge eating typically emerged first for BED. Regarding cognitive symptoms, for AN, weight/shape overvaluation typically emerged first, whereas for BN, BED, and PD, overvaluation typically emerged simultaneously with feeling fat and fear of weight gain. Binge eating, compensatory behaviors, weight/shape overvaluation, fear of weight gain, and feeling fat predicted BN, BED, and PD onset, whereas weight/shape overvaluation, fear of weight gain, and lower than expected body mass index predicted AN onset. Predictive effects of prodromal symptoms were similar in magnitude to those of established risk factors: Collectively, prodromal symptoms and risk factors predicted onset of specific eating disorders with 67-83% accuracy. Results suggest that compensatory weight control behaviors and cognitive symptoms are likely to emerge before binge eating in the various eating disorders and that offering indicated prevention programs to youth with prodromal symptoms may be an effective way to prevent eating disorders. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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Domínguez-Muñoz, D. A., Jiménez‐Zamarripa, C. A., Cruz-Trujillo, R., Flores-Guillén, E., Jacome, A. P., Tejas-Juárez, J. G., Briones-Aranda, A., Corzo-Gómez, J. C., Espinosa‐Juárez, J. V., Ortiz, A. P., et al. (2025) · Adolescents · doi:10.3390/adolescents5040080
Stice, E. M., & Yamamiya, Y. (2026) · Behaviour Research and Therapy · doi:10.1016/j.brat.2026.104984
Self-citationZhao, P., Xu, J., Ma, X., & Wang, H. (2026) · Body Image · doi:10.1016/j.bodyim.2026.102090
Stice, E. M., Rohde, P., Gau, J. M., & Shaw, H. E. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70775
Self-citationGribsholt, S. B., Christensen, M. B., Kristensen, K., Rokkedal, K., Solskov, L. J., Clausen, L., & Abild, C. B. (2026) · Primary care diabetes · doi:10.1016/j.pcd.2026.05.002
Juergensen, V., Halbeisen, G., Lehe, M. S., & Paslakis, G. (2026) · Journal of Eating Disorders · doi:10.1186/s40337-026-01616-8
Yamamiya, Y., & Stice, E. M. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15103872
Self-citationSpivak‐Lavi, Z., Tzischinsky, O., & Latzer, Y. (2026) · Current Psychology · doi:10.1007/s12144-026-09531-6
Family Functioning Among Adolescents With Avoidant/Restrictive Food Intake Disorder
Rienecke, R. D., Manwaring, J. L., Anderson, K., Duffy, A., Joiner, T. E., Mehler, P. S., & Blalock, D. V. (2026) · European Eating Disorders Review · doi:10.1002/erv.70137
de Matos, D. C. M., Marques, E. S., Vaz, J. D. S., Buffarini, R., & Vilela, A. A. F. (2026) · Appetite Disordered Eating · doi:10.1016/j.appde.2026.100002
Wälte, D., Himmerich, H., & Schneider, F. (2026) · Springer eBooks · doi:10.1007/978-3-662-70668-8_27
Barnhart, W. R., Chen, X., Xiao, Y., Li, Y., Nagata, J. M., Smith, A., & He, J. (2026) · Body Image · doi:10.1016/j.bodyim.2026.102188
Lavoie, C., Carbonneau, N., Truong, C., & Marin, M. (2026) · Appetite Disordered Eating · doi:10.1016/j.appde.2026.100011
Imahori, K., Yamamiya, Y., & Stice, E. M. (2026) · International Journal of Eating Disorders · doi:10.1002/eat.70240
Self-citation
- Authors
- Stice, E., Desjardins, C. D., Rohde, P., & Shaw, H.
- Affiliations
- Stanford Medicine (US)
- Saint Michael's College (US)
- Oregon Research Institute (US)
- Venue
- Journal of Abnormal Psychology
- Published
- 2021-05
- Volume
- 130
- Issue
- 4
- Pages
- 377-387
- ISSN
- 0021-843X (ISSN-L)
- 1939-1846
- PMC
- PMC8244173
- OpenAlex
- W3177337946
- Cited by
- 81
- References
- 32
- Citations by year
- 2026: 17 · 2025: 20 · 2024: 15 · 2023: 13 · 2022: 14 · 2021: 2
- FWCI
- 7.50
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Abnormal Psychology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH070699, R01MH086582, R01MH097720)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- anorexia nervosa, bulimia nervosa, binge eating disorder, purging disorder, eating disorder onset, prodromal symptoms, fear of weight gain, body image concern, eating disorder prevention, young women, risk factors
- MeSH terms
- Adolescent, Adult, Anorexia Nervosa, Feeding and Eating Disorders, Body Image, Female, Forecasting, Humans, Risk Factors, Bulimia Nervosa, Young Adult, Binge-Eating Disorder, Prodromal Symptoms
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